|
|
| Line 37: |
Line 37: |
|
| |
|
|
| |
|
| Wolff-Parkinson-White syndrome (WPW) is a syndrome of pre-excitation of the [[Ventricle (heart)|ventricles]] of the [[heart]] due to an [[accessory pathway]] known as the ''[[Bundle of Kent]]''. This accessory pathway is a congenital abnormal electrical communication from the [[atrium (anatomy)|atria]] to the [[ventricles]] causing them to contract prematurely, resulting in a unique type of [[supraventricular tachycardia]] referred to as an [[Supraventricular_tachycardia#Types|atrioventricular reciprocating tachycardia]]. The accessory pathway is the consequence of the lack of complete fusion between the suculus and the endocardiac cushion tissue which should be completed by the 12th week of gestation.<ref name="WesselsMarkman1996">{{cite journal|last1=Wessels|first1=A.|last2=Markman|first2=M.W.M.|last3=Vermeulen|first3=J.L.M.|last4=Anderson|first4=R.H.|last5=Moorman|first5=A.F.M.|last6=Lamers|first6=W.H.|title=The Development of the Atrioventricular Junction in the Human Heart|journal=Circulation Research|volume=78|issue=1|year=1996|pages=110–117|issn=0009-7330|doi=10.1161/01.RES.78.1.110}}</ref><ref name="Ho2008">{{cite journal|last1=Ho|first1=S. Y.|title=Accessory Atrioventricular Pathways: Getting to the Origins|journal=Circulation|volume=117|issue=12|year=2008|pages=1502–1504|issn=0009-7322|doi=10.1161/CIRCULATIONAHA.107.764035}}</ref>
| |
|
| |
| The incidence of WPW syndrome is between 0.1 and 0.3% of the general population.<ref name="pmid22579340">{{cite journal| author=Pediatric and Congenital Electrophysiology Society (PACES). Heart Rhythm Society (HRS). American College of Cardiology Foundation (ACCF). American Heart Association (AHA). American Academy of Pediatrics (AAP). Canadian Heart Rhythm Society (CHRS) et al.| title=PACES/HRS expert consensus statement on the management of the asymptomatic young patient with a Wolff-Parkinson-White (WPW, ventricular preexcitation) electrocardiographic pattern: developed in partnership between the Pediatric and Congenital Electrophysiology Society (PACES) and the Heart Rhythm Society (HRS). Endorsed by the governing bodies of PACES, HRS, the American College of Cardiology Foundation (ACCF), the American Heart Association (AHA), the American Academy of Pediatrics (AAP), and the Canadian Heart Rhythm Society (CHRS). | journal=Heart Rhythm | year= 2012 | volume= 9 | issue= 6 | pages= 1006-24 | pmid=22579340 | doi=10.1016/j.hrthm.2012.03.050 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22579340 }} </ref><ref name = Rosner_et_al_1999>
| |
| {{cite journal
| |
| | author=Rosner MH, Brady WJ Jr, Kefer MP, Martin ML.
| |
| | title=Electrocardiography in the patient with the Wolff-Parkinson-White syndrome: diagnostic and initial therapeutic issues
| |
| | journal=American Journal of Emergency Medicine
| |
| | volume=17
| |
| | issue=7
| |
| | year=1999
| |
| | pages=705-14
| |
| | id=PMID 10597097}}</ref><ref name = Sorbo_et_al_1995>
| |
| {{cite journal
| |
| | author=Sorbo MD, Buja GF, Miorelli M, Nistri S, Perrone C, Manca S, Grasso F, Giordano GM, Nava A.
| |
| | title=The prevalence of the Wolff-Parkinson-White syndrome in a population of 116,542 young males
| |
| | journal=Giornale Italiano di Cardiologia
| |
| | volume=25
| |
| | issue=6
| |
| | year=1995
| |
| | pages=681-7
| |
| | id=PMID 7649416
| |
| | language = Italian }}</ref><ref name = Munger_et_al_1993>
| |
| {{cite journal
| |
| | author=Munger TM, Packer DL, Hammill SC, Feldman BJ, Bailey KR, Ballard DJ, Holmes DR Jr, Gersh BJ.
| |
| | title=A population study of the natural history of Wolff-Parkinson-White syndrome in Olmsted County, Minnesota, 1953-1989
| |
| | journal=Circulation.
| |
| | volume=87
| |
| | issue=3
| |
| | year=1993
| |
| | pages=866-73
| |
| | id=PMID 8443907}}</ref>
| |
|
| |
| The majority of individuals with WPW syndrome doesn't present symptoms, nearly 65% of adolescents and 40% of adults present ECG changes but remain [[asymptomatic]]. Though risk of sudden death is associated with WPW, is a very rare condition. Last reports show an incidence of 4.5 per 1000 patients with WPW presented with sudden death.<ref name="pmid22579340">{{cite journal| author=Pediatric and Congenital Electrophysiology Society (PACES). Heart Rhythm Society (HRS). American College of Cardiology Foundation (ACCF). American Heart Association (AHA). American Academy of Pediatrics (AAP). Canadian Heart Rhythm Society (CHRS) et al.| title=PACES/HRS expert consensus statement on the management of the asymptomatic young patient with a Wolff-Parkinson-White (WPW, ventricular preexcitation) electrocardiographic pattern: developed in partnership between the Pediatric and Congenital Electrophysiology Society (PACES) and the Heart Rhythm Society (HRS). Endorsed by the governing bodies of PACES, HRS, the American College of Cardiology Foundation (ACCF), the American Heart Association (AHA), the American Academy of Pediatrics (AAP), and the Canadian Heart Rhythm Society (CHRS). | journal=Heart Rhythm | year= 2012 | volume= 9 | issue= 6 | pages= 1006-24 | pmid=22579340 | doi=10.1016/j.hrthm.2012.03.050 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22579340 }} </ref>
| |
|
| |
|
| ==References== | | ==References== |