Burn pathophysiology

Burn Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Eman Alademi, M.D.[2]

Pathophysiology

It is thought that burns is the result of damage to the skin caused by either excessive heat or caustic chemicals.

Gross Pathology

Images courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology

Trachea, thermal burn smoke inhalation

Lung, thermal burn smoke inhalation

Ischemia: Gross natural color close-up of liver with shock necrosis and a large area of necrosis beneath capsule quite good burn sepsis DIC

Small intestine: Ischemia: Gross natural color frankly gangrenous gut shown rather close-up excellent example burn sepsis DIC

Kidney: Bilateral Cortical Necrosis: Gross natural color excellent gross example showing capsular and cut surfaces burn case

Kidney: Acute Tubular Necrosis: Gross good example swollen cortex secondary to body burn

Kidney: Acute Pyelonephritis: Gross cut surface obvious abscesses burn case with Pseudomonas sepsis

Brain: Bacterial Meningitis: Gross base of frontal lobes well shown meningitis burn case with Pseudomonas sepsis

Stomach: Curlings Ulcers: Gross natural color multiple superficial mucosal ulcers well shown in fundus and prepyloric area in lesser curvature. A good example of burn patient

Thyroid: Fibrosis: Gross natural color cross section into fibrotic and apparently contracted gland can be used as an example of burned out thyroiditis or what we used to call Riedels struma