Pre-eclampsia primary prevention: Difference between revisions
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*In a recent clinical trial, there was 62% reduction in the occurrence of [[preeclampsia]] in patients received 150 mg aspirin daily. | *In a recent clinical trial, there was 62% reduction in the occurrence of [[preeclampsia]] in patients received 150 mg aspirin daily. | ||
* There is not strong evidence about the effectiveness of [[vitamin C]], [[vitamin E ]], [[folic acid]] , [[sodium restriction]], for prevention of [[preeclampsia]] | * There is not strong evidence about the effectiveness of [[vitamin C]], [[vitamin E ]], [[folic acid]] , [[sodium restriction]], for prevention of [[preeclampsia]].<ref name="pmid18254042">{{cite journal |vauthors=Rumbold A, Duley L, Crowther CA, Haslam RR |title=Antioxidants for preventing pre-eclampsia |journal=Cochrane Database Syst Rev |volume= |issue=1 |pages=CD004227 |date=January 2008 |pmid=18254042 |pmc=6718237 |doi=10.1002/14651858.CD004227.pub3 |url=}}</ref> | ||
Revision as of 11:25, 7 October 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Zand, M.D.[2]
Primary prevention
- Effective measures for the primary prevention of preeclampsia include administration of low dose aspirin before the 16th week of pregnancy.[1][2]
- In a recent clinical trial, there was 62% reduction in the occurrence of preeclampsia in patients received 150 mg aspirin daily.
- There is not strong evidence about the effectiveness of vitamin C, vitamin E , folic acid , sodium restriction, for prevention of preeclampsia.[3]
With regard to nutritional
interventions, evidence is insufficient to demonstrate
effectiveness for vitamins C and E (90), fish oil (91),
garlic supplementation (92), vitamin D (93), folic acid
(94) or sodium restriction (95) for reducing the risk of
preeclampsia. A meta-analysis of 13 trials (15,730
women) reported a significant reduction in preeclampsia
with calcium supplementation, with the greatest effect
among women with low-baseline calcium intake (96).
References
- ↑ Rolnik, Daniel L.; Wright, David; Poon, Liona C.; O’Gorman, Neil; Syngelaki, Argyro; de Paco Matallana, Catalina; Akolekar, Ranjit; Cicero, Simona; Janga, Deepa; Singh, Mandeep; Molina, Francisca S.; Persico, Nicola; Jani, Jacques C.; Plasencia, Walter; Papaioannou, George; Tenenbaum-Gavish, Kinneret; Meiri, Hamutal; Gizurarson, Sveinbjorn; Maclagan, Kate; Nicolaides, Kypros H. (2017). "Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia". New England Journal of Medicine. 377 (7): 613–622. doi:10.1056/NEJMoa1704559. ISSN 0028-4793.
- ↑ Mayrink, J.; Costa, M. L.; Cecatti, J. G. (2018). "Preeclampsia in 2018: Revisiting Concepts, Physiopathology, and Prediction". The Scientific World Journal. 2018: 1–9. doi:10.1155/2018/6268276. ISSN 2356-6140.
- ↑ Rumbold A, Duley L, Crowther CA, Haslam RR (January 2008). "Antioxidants for preventing pre-eclampsia". Cochrane Database Syst Rev (1): CD004227. doi:10.1002/14651858.CD004227.pub3. PMC 6718237 Check
|pmc=value (help). PMID 18254042.