Tremor surgery: Difference between revisions
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**Most common [[side effect]] is [[dysarthria]], [[cognitive]] impairment, and imbalance. | **Most common [[side effect]] is [[dysarthria]], [[cognitive]] impairment, and imbalance. | ||
**It is an invasive [[procedure]]. | **It is an invasive [[procedure]]. | ||
*[[Deep brain stimulation]]: | *[[Deep brain stimulation]]<ref name="pmid18394574">{{cite journal| author=Lyons KE, Pahwa R| title=Deep brain stimulation and tremor. | journal=Neurotherapeutics | year= 2008 | volume= 5 | issue= 2 | pages= 331-8 | pmid=18394574 | doi=10.1016/j.nurt.2008.01.004 | pmc=5084174 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18394574 }} </ref>: | ||
**[[Parkinson's disease]] and [[essential tremor]] may benefit from [[deep brain stimulation]]. | **[[Parkinson's disease]] and [[essential tremor]] may benefit from [[deep brain stimulation]]. | ||
**In this non-invasive procedure [[electrodes]] are [[implanted]] to send high-[[frequency]] [[electrical]] signals to the [[thalamus]], [[substantia nigra]], or [[globus pallidus]]. Downside of [[deep brain stimulation]] is the expense, and long term benefits are not established. It is reversible. | **In this non-invasive procedure [[electrodes]] are [[implanted]] to send high-[[frequency]] [[electrical]] signals to the [[thalamus]], [[substantia nigra]], or [[globus pallidus]]. Downside of [[deep brain stimulation]] is the expense, and long term benefits are not established. It is reversible. |
Revision as of 03:42, 29 January 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Surgery
- Botulinum neurotoxin injections:
- Thalamotomy:
- Helpful in medication resistant essential tremor, cerebellar tremor, or Parkinson's disease related tremor.
- Tremor is permanently treated by creating lesions in thalamus responsible for causing tremors.
- Most common side effect is dysarthria, cognitive impairment, and imbalance.
- It is an invasive procedure.
- Deep brain stimulation[2]:
- Parkinson's disease and essential tremor may benefit from deep brain stimulation.
- In this non-invasive procedure electrodes are implanted to send high-frequency electrical signals to the thalamus, substantia nigra, or globus pallidus. Downside of deep brain stimulation is the expense, and long term benefits are not established. It is reversible.
- Magnetic resonance-guided focused ultrasound (MRgFUS),
- Radio-surgical gamma knife thalamotomy.
References
- ↑ Niemann N, Jankovic J (2018). "Botulinum Toxin for the Treatment of Hand Tremor". Toxins (Basel). 10 (7). doi:10.3390/toxins10070299. PMC 6070882. PMID 30029483.
- ↑ Lyons KE, Pahwa R (2008). "Deep brain stimulation and tremor". Neurotherapeutics. 5 (2): 331–8. doi:10.1016/j.nurt.2008.01.004. PMC 5084174. PMID 18394574.