Tremor surgery: Difference between revisions
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*[[Botulinum]] [[neurotoxin]] [[injections]]: | *[[Botulinum]] [[neurotoxin]] [[injections]]: | ||
**It has shown improvement in [[patients]] with [[hand]] tremor, regardless of the [[etiology]]<ref name="pmid30029483">{{cite journal| author=Niemann N, Jankovic J| title=Botulinum Toxin for the Treatment of Hand Tremor. | journal=Toxins (Basel) | year= 2018 | volume= 10 | issue= 7 | pages= | pmid=30029483 | doi=10.3390/toxins10070299 | pmc=6070882 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30029483 }} </ref>. | **It has shown improvement in [[patients]] with [[hand]] tremor, regardless of the [[etiology]]<ref name="pmid30029483">{{cite journal| author=Niemann N, Jankovic J| title=Botulinum Toxin for the Treatment of Hand Tremor. | journal=Toxins (Basel) | year= 2018 | volume= 10 | issue= 7 | pages= | pmid=30029483 | doi=10.3390/toxins10070299 | pmc=6070882 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30029483 }} </ref>. | ||
*[[Thalamotomy]]: | *[[Thalamotomy]]<ref name="pmid23154796">{{cite journal| author=Bahgat D, Magill ST, Berk C, McCartney S, Burchiel KJ| title=Thalamotomy as a treatment option for tremor after ineffective deep brain stimulation. | journal=Stereotact Funct Neurosurg | year= 2013 | volume= 91 | issue= 1 | pages= 18-23 | pmid=23154796 | doi=10.1159/000342491 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23154796 }} </ref>: | ||
**Helpful in [[medication]] [[resistant]] [[essential tremor]], [[cerebellar]] tremor, or [[Parkinson's disease]] related tremor. | **Helpful in [[medication]] [[resistant]] [[essential tremor]], [[cerebellar]] tremor, or [[Parkinson's disease]] related tremor. | ||
**Tremor is permanently treated by creating [[lesions]] in [[thalamus]] responsible for causing tremors. | **Tremor is permanently treated by creating [[lesions]] in [[thalamus]] responsible for causing tremors. | ||
Revision as of 03:44, 29 January 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Surgery
- Botulinum neurotoxin injections:
- Thalamotomy[2]:
- Helpful in medication resistant essential tremor, cerebellar tremor, or Parkinson's disease related tremor.
- Tremor is permanently treated by creating lesions in thalamus responsible for causing tremors.
- Most common side effect is dysarthria, cognitive impairment, and imbalance.
- It is an invasive procedure.
- Deep brain stimulation[3]:
- Parkinson's disease and essential tremor may benefit from deep brain stimulation.
- In this non-invasive procedure electrodes are implanted to send high-frequency electrical signals to the thalamus, substantia nigra, or globus pallidus. Downside of deep brain stimulation is the expense, and long term benefits are not established. It is reversible.
- Magnetic resonance-guided focused ultrasound (MRgFUS),
- Radio-surgical gamma knife thalamotomy.
References
- ↑ Niemann N, Jankovic J (2018). "Botulinum Toxin for the Treatment of Hand Tremor". Toxins (Basel). 10 (7). doi:10.3390/toxins10070299. PMC 6070882. PMID 30029483.
- ↑ Bahgat D, Magill ST, Berk C, McCartney S, Burchiel KJ (2013). "Thalamotomy as a treatment option for tremor after ineffective deep brain stimulation". Stereotact Funct Neurosurg. 91 (1): 18–23. doi:10.1159/000342491. PMID 23154796.
- ↑ Lyons KE, Pahwa R (2008). "Deep brain stimulation and tremor". Neurotherapeutics. 5 (2): 331–8. doi:10.1016/j.nurt.2008.01.004. PMC 5084174. PMID 18394574.