Polycythemia epidemiology and demographics: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
|||
| Line 1: | Line 1: | ||
__NOTOC__ | __NOTOC__ | ||
{{Polycythemia}} | {{Polycythemia}} | ||
{{CMG}}{{AE}}{{Debduti}} | {{CMG}} ; {{AE}} {{Debduti}} | ||
==Overview== | ==Overview== | ||
* Not usually diagnosed in individuals below 60 years age. Slightly more prevalent in men than in women according to some studies. | * Not usually diagnosed in individuals below 60 years of age. Slightly more prevalent in men than in women according to some studies. | ||
==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
| Line 17: | Line 17: | ||
===Case-fatality rate/Mortality rate=== | ===Case-fatality rate/Mortality rate=== | ||
* 4 year mortality rate is >10%. | * 4-year mortality rate is >10%. | ||
*On | *On average patients lived with the disease for 8.6 years (mean), the cases that were fatal were approximately 77.1 years of age on average. | ||
*Comorbidities such as cardiovascular diseases, other blood and lymphatic disorders, vascular disorders, mass occupying lesions in the thorax, respiratory system, infections, etc accounted for more deaths more often. | *Comorbidities such as cardiovascular diseases, other blood, and lymphatic disorders, vascular disorders, mass occupying lesions in the thorax, respiratory system, infections, etc accounted for more deaths more often. | ||
*Thrombotic complications were the most common cause of death followed by hematologic malignancy. <ref name="urlwww.hematologyadvisor.com">{{cite web |url=https://www.hematologyadvisor.com/home/conference-coverage/ash-2020/assessing-mortality-rates-causes-of-death-in-polycythemia-vera/ |title=www.hematologyadvisor.com |format= |work= |accessdate=}}</ref> | *Thrombotic complications were the most common cause of death followed by hematologic malignancy. <ref name="urlwww.hematologyadvisor.com">{{cite web |url=https://www.hematologyadvisor.com/home/conference-coverage/ash-2020/assessing-mortality-rates-causes-of-death-in-polycythemia-vera/ |title=www.hematologyadvisor.com |format= |work= |accessdate=}}</ref> | ||
| Line 41: | Line 41: | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{WS}} | |||
{{WH}} | |||
[[Category:Hematology]] | [[Category:Hematology]] | ||
[[Category:Emergency medicine]] | [[Category:Emergency medicine]] | ||
| Line 47: | Line 48: | ||
[[Category:Blood disorders]] | [[Category:Blood disorders]] | ||
[[Category:Up-To-Date]] | [[Category:Up-To-Date]] | ||
Revision as of 16:17, 2 March 2021
|
Polycythemia Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Polycythemia epidemiology and demographics On the Web |
|
American Roentgen Ray Society Images of Polycythemia epidemiology and demographics |
|
Risk calculators and risk factors for Polycythemia epidemiology and demographics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Debduti Mukhopadhyay, M.B.B.S[2]
Overview
- Not usually diagnosed in individuals below 60 years of age. Slightly more prevalent in men than in women according to some studies.
Epidemiology and Demographics
Incidence
- The incidence of polycythemia vera is approximately 1.9 per 100,000 individuals in the United States.
- Taking into account all races and ethnicities, the incidence is approximately 2.8 per 100,000 males and 1.3 per 100,000 in females. [1]
Prevalence
- The prevalence of polycythemia vera in the 7 MM countries was 283,442 in 2017.
- Prevalence of polycythemia vera was the highest in the US in 2017 at 157,290, out of which 62,916 cases were asymptomatic and 94,374 were symptomatic. [2]
- 22 cases per 100,000 people. [1]
Case-fatality rate/Mortality rate
- 4-year mortality rate is >10%.
- On average patients lived with the disease for 8.6 years (mean), the cases that were fatal were approximately 77.1 years of age on average.
- Comorbidities such as cardiovascular diseases, other blood, and lymphatic disorders, vascular disorders, mass occupying lesions in the thorax, respiratory system, infections, etc accounted for more deaths more often.
- Thrombotic complications were the most common cause of death followed by hematologic malignancy. [3]
Age
- It has been noted that PV is more common in the age group >75. [2]
- Median age of diagnosis is 60. [4]
Race
- Jews of Eastern European descent have a higher number of cases as compared to other Europeans or Asians. [1]
Gender
- Generally, there is no sex predeliction.[4]
- In the analysis for the 7 MM countries, the percentage of prevalent males was higher than prevalent females. [2]
Region
Developed Countries
Developing Countries
References
- ↑ 1.0 1.1 1.2 "www.lls.org" (PDF).
- ↑ 2.0 2.1 2.2 "Polycythemia Vera (PV): Trends, Epidemiology (2017-2030), KOL Views and Unmet Needs".
- ↑ "www.hematologyadvisor.com".
- ↑ 4.0 4.1 4.2 Lu X, Chang R. PMID 32491592 Check
|pmid=value (help). Missing or empty|title=(help) - ↑ Johansson P (April 2006). "Epidemiology of the myeloproliferative disorders polycythemia vera and essential thrombocythemia". Semin Thromb Hemost. 32 (3): 171–3. doi:10.1055/s-2006-939430. PMID 16673273.