Amnesia differential diagnosis: Difference between revisions

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|- style="background: #4479BA; color: #FFFFFF; text-align: center;"
|- style="background: #4479BA; color: #FFFFFF; text-align: center;"
! rowspan="2"  style="background: #4479BA; color: #FFFFFF; text-align: center;|Diseases
! rowspan="2"  style="background: #4479BA; color: #FFFFFF; text-align: center;|Diseases
| colspan="7" rowspan="1"  style="background: #4479BA; color: #FFFFFF; text-align: center;|'''Differentiating Features'''
| colspan="3" rowspan="1"  style="background: #4479BA; color: #FFFFFF; text-align: center;|'''Differentiating Features'''
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! style="background: #4479BA; color: #FFFFFF; text-align: center;|Duration of Amnesia
! style="background: #4479BA; color: #FFFFFF; text-align: center;|Duration of Amnesia
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| style="background: #F5F5F5; padding: 5px;" |[[Head]] [[Trauma]]
| style="background: #F5F5F5; padding: 5px;" |[[Head]] [[Trauma]]
| style="background: #F5F5F5; padding: 5px;" |Variable, depends on the extent of [[brain]] [[injury]]
| style="background: #F5F5F5; padding: 5px;" |Variable, depends on the extent of [[brain]] [[injury]]
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Dissociative Amnesia]]
| style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Dissociative Amnesia]]
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| style="background: #F5F5F5; padding: 5px;" |Usually follows an incident that caused a lot of  [[stress]] and [[trauma]]
| style="background: #F5F5F5; padding: 5px;" |Usually follows an incident that caused a lot of  [[stress]] and [[trauma]]
| style="background: #F5F5F5; padding: 5px;" |No [[cognitive impairment]]
| style="background: #F5F5F5; padding: 5px;" |No [[cognitive impairment]]
| style="background: #F5F5F5; padding: 5px;" |
| style="background: #F5F5F5; padding: 5px;" |
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Transient global amnesia]]
| style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Transient global amnesia]]
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| style="background: #F5F5F5; padding: 5px;" |[[Brain]] [[ischemia]], [[migraine]], [[seizure]], [[venous congestion]], [[psychological trauma]].
| style="background: #F5F5F5; padding: 5px;" |[[Brain]] [[ischemia]], [[migraine]], [[seizure]], [[venous congestion]], [[psychological trauma]].
| style="background: #F5F5F5; padding: 5px;" |No [[cognitive impairment]]
| style="background: #F5F5F5; padding: 5px;" |No [[cognitive impairment]]
| style="background: #F5F5F5; padding: 5px;" |
| style="background: #F5F5F5; padding: 5px;" |
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Drug]]-Induced Amnesia
| style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Drug]]-Induced Amnesia
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| style="background: #F5F5F5; padding: 5px;" |[[Benzodiazepines]]
| style="background: #F5F5F5; padding: 5px;" |[[Benzodiazepines]]
| style="background: #F5F5F5; padding: 5px;" |No [[cognitive impairment]]
| style="background: #F5F5F5; padding: 5px;" |No [[cognitive impairment]]
| style="background: #F5F5F5; padding: 5px;" |
| style="background: #F5F5F5; padding: 5px;" |
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |Neurological Amnesia
| style="background: #DCDCDC; padding: 5px; text-align: center;" |Neurological Amnesia
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| style="background: #F5F5F5; padding: 5px;" |[[Alzheimer's disease]], [[Pick's disease]], [[Parkinson's disease]]
| style="background: #F5F5F5; padding: 5px;" |[[Alzheimer's disease]], [[Pick's disease]], [[Parkinson's disease]]
| style="background: #F5F5F5; padding: 5px;" |Progressive [[cognitive impairment]]
| style="background: #F5F5F5; padding: 5px;" |Progressive [[cognitive impairment]]
| style="background: #F5F5F5; padding: 5px;" |
| style="background: #F5F5F5; padding: 5px;" |
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |Transient epileptic amnesia<ref name="pmid9576532">{{cite journal| author=Zeman AZ, Boniface SJ, Hodges JR| title=Transient epileptic amnesia: a description of the clinical and neuropsychological features in 10 cases and a review of the literature. | journal=J Neurol Neurosurg Psychiatry | year= 1998 | volume= 64 | issue= 4 | pages= 435-43 | pmid=9576532 | doi=10.1136/jnnp.64.4.435 | pmc=2170058 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9576532  }} </ref>
| style="background: #DCDCDC; padding: 5px; text-align: center;" |Transient epileptic amnesia<ref name="pmid9576532">{{cite journal| author=Zeman AZ, Boniface SJ, Hodges JR| title=Transient epileptic amnesia: a description of the clinical and neuropsychological features in 10 cases and a review of the literature. | journal=J Neurol Neurosurg Psychiatry | year= 1998 | volume= 64 | issue= 4 | pages= 435-43 | pmid=9576532 | doi=10.1136/jnnp.64.4.435 | pmc=2170058 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9576532  }} </ref>
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| style="background: #F5F5F5; padding: 5px;" |History of [[temporal lobe]] [[epilepsy]]
| style="background: #F5F5F5; padding: 5px;" |History of [[temporal lobe]] [[epilepsy]]
| style="background: #F5F5F5; padding: 5px;" |No [[cognitive impairment]]
| style="background: #F5F5F5; padding: 5px;" |No [[cognitive impairment]]
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Revision as of 15:26, 23 March 2021

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Zehra Malik, M.B.B.S[2]

Overview

The underlying etiology of memory loss must be differentiated on the basis of duration of memory loss, presence of anterograde amnesia or retrograde amnesia, associated features, and cognitive impairment.

Amnesia Differential Diagnosis

Diseases Differentiating Features
Duration of Amnesia Associated Features Cognitive Impairment Feature 4 Feature 5 Feature 6
Post-traumatic amnesia Varies Head Trauma Variable, depends on the extent of brain injury
Dissociative Amnesia Variable. Could last minutes, hours, or rarely even months or years Usually follows an incident that caused a lot of stress and trauma No cognitive impairment
Transient global amnesia Less than 24hrs Brain ischemia, migraine, seizure, venous congestion, psychological trauma. No cognitive impairment
Drug-Induced Amnesia Once drug is stopped, memory gradually regained Benzodiazepines No cognitive impairment
Neurological Amnesia Does not resolve, patient experiences progressive memory loss. Alzheimer's disease, Pick's disease, Parkinson's disease Progressive cognitive impairment
Transient epileptic amnesia[3] Episodic transient amnesia History of temporal lobe epilepsy No cognitive impairment

References

  1. Waldemar G, Dubois B, Emre M, Georges J, McKeith IG, Rossor M; et al. (2007). "Recommendations for the diagnosis and management of Alzheimer's disease and other disorders associated with dementia: EFNS guideline". Eur J Neurol. 14 (1): e1–26. doi:10.1111/j.1468-1331.2006.01605.x. PMID 17222085.
  2. Diagnostic and statistical manual of mental disorders : DSM-5. Washington, D.C: American Psychiatric Association. 2013. ISBN 0890425558.
  3. Zeman AZ, Boniface SJ, Hodges JR (1998). "Transient epileptic amnesia: a description of the clinical and neuropsychological features in 10 cases and a review of the literature". J Neurol Neurosurg Psychiatry. 64 (4): 435–43. doi:10.1136/jnnp.64.4.435. PMC 2170058. PMID 9576532.

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