Pancreatic fistula laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
Pleural or ascitic fluid should be sent for analysis. An elevated amylase level, usually > 1,000 IU/L, with protein levels over 3.0 g/dL is diagnostic. [[Complete blood count]] is necessary to check for any ongoing [[infection]] or [[hemorrhage]]. Complete metabolic panel including [[inflammatory]] markers, [[Electrolyte|serum electrolytes]], [[liver function tests]], [[calcium]], [[albumin]], [[amylase]] and [[lipase]] should be sent to [[laboratory]] for evaluation. Furthermore, [[pancreatic]] [[fistula]] leak presenting as [[ascites]] or [[pleural effusion]] should be analyzed for fluid [[protein]], [[albumin]], [[lactate dehydrogenase]], [[glucose]], gram cultures and total cell count. | |||
==Laboratory Findings== | ==Laboratory Findings== | ||
* Pleural or ascitic fluid should be sent for analysis. | * Bulleted list item | ||
Fluid samples collected via [[thoracentesis]], [[paracentesis]] or fluid collected via [[percutaneous]] drainage from an external [[fistula]] can be analyzed for [[amylase]] level, which helps solidify the diagnosis of [[pancreatic cancer]]. | |||
* Bulleted list item | |||
[[Complete blood count]] is necessary to check for any ongoing [[infection]] or [[hemorrhage]]. Complete metabolic panel including [[inflammatory]] markers, [[Electrolyte|serum electrolytes]], [[liver function tests]], [[calcium]], [[albumin]], [[amylase]] and [[lipase]] should be sent to [[laboratory]] for evaluation. | |||
* Bulleted list item | |||
Furthermore, [[pancreatic]] [[fistula]] leak presenting as [[ascites]] or [[pleural effusion]] should be analyzed for fluid [[protein]], [[albumin]], [[lactate dehydrogenase]], [[glucose]], gram cultures and total cell count. [[Pancreatic]] fluid [[amylase]] level will be >1000 u/dl.<ref name="pmid24650171">{{cite journal| author=Larsen M, Kozarek R| title=Management of pancreatic ductal leaks and fistulae. | journal=J Gastroenterol Hepatol | year= 2014 | volume= 29 | issue= 7 | pages= 1360-70 | pmid=24650171 | doi=10.1111/jgh.12574 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24650171 }} </ref><ref name="pmid18053844">{{cite journal| author=Morgan KA, Adams DB| title=Management of internal and external pancreatic fistulas. | journal=Surg Clin North Am | year= 2007 | volume= 87 | issue= 6 | pages= 1503-13, x | pmid=18053844 | doi=10.1016/j.suc.2007.08.008 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18053844 }} </ref> | |||
* Bulleted list item | |||
Pleural or ascitic fluid should be sent for analysis. | |||
** An elevated amylase level, usually > 1,000 IU/L, with protein levels over 3.0 g/dL is diagnostic. | ** An elevated amylase level, usually > 1,000 IU/L, with protein levels over 3.0 g/dL is diagnostic. | ||
==References== | ==References== |
Revision as of 19:15, 25 March 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pleural or ascitic fluid should be sent for analysis. An elevated amylase level, usually > 1,000 IU/L, with protein levels over 3.0 g/dL is diagnostic. Complete blood count is necessary to check for any ongoing infection or hemorrhage. Complete metabolic panel including inflammatory markers, serum electrolytes, liver function tests, calcium, albumin, amylase and lipase should be sent to laboratory for evaluation. Furthermore, pancreatic fistula leak presenting as ascites or pleural effusion should be analyzed for fluid protein, albumin, lactate dehydrogenase, glucose, gram cultures and total cell count.
Laboratory Findings
- Bulleted list item
Fluid samples collected via thoracentesis, paracentesis or fluid collected via percutaneous drainage from an external fistula can be analyzed for amylase level, which helps solidify the diagnosis of pancreatic cancer.
- Bulleted list item
Complete blood count is necessary to check for any ongoing infection or hemorrhage. Complete metabolic panel including inflammatory markers, serum electrolytes, liver function tests, calcium, albumin, amylase and lipase should be sent to laboratory for evaluation.
- Bulleted list item
Furthermore, pancreatic fistula leak presenting as ascites or pleural effusion should be analyzed for fluid protein, albumin, lactate dehydrogenase, glucose, gram cultures and total cell count. Pancreatic fluid amylase level will be >1000 u/dl.[1][2]
- Bulleted list item
Pleural or ascitic fluid should be sent for analysis.
- An elevated amylase level, usually > 1,000 IU/L, with protein levels over 3.0 g/dL is diagnostic.
References
- ↑ Larsen M, Kozarek R (2014). "Management of pancreatic ductal leaks and fistulae". J Gastroenterol Hepatol. 29 (7): 1360–70. doi:10.1111/jgh.12574. PMID 24650171.
- ↑ Morgan KA, Adams DB (2007). "Management of internal and external pancreatic fistulas". Surg Clin North Am. 87 (6): 1503–13, x. doi:10.1016/j.suc.2007.08.008. PMID 18053844.