Acrodermatitis chronica atrophicans pathophysiology: Difference between revisions
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==Overview== | |||
==Pathophysiology== | ==Pathophysiology== | ||
This progressive skin process is due to the effect of | ===Pathogenesis=== | ||
*This progressive [[skin]] process is due to the effect of [[Chronic (medical)|chronic]] [[infection]] with the [[spirochete]] [[borrelia burgdorferi]]. [[Borrelia|Borrelia afzelii]] is the predominant [[pathophysiology]], but may not be the exclusive, [[etiology]] of [[acrodermatitis chronica atrophicans]]. | |||
*[[Borrelia|Borrelia garinii]] has also been detected in some [[patients]]. | |||
==Genetics== | |||
==Associated Conditions== | |||
Conditions associated with [disease name] include: | |||
==Gross Pathology== | |||
On gross pathology, [feature1], [feature2], and [feature3] are characteristic findings of [disease name]. | |||
===Microscopic Pathology=== | ===Microscopic Pathology=== | ||
* Light and electron microscopic study of the [[skin biopsy]] shows degeneration of the [[elastica]] and [[collagen]] fibers.<ref name="pmid7751475">{{cite journal |author=de Koning J, Tazelaar DJ, Hoogkamp-Korstanje JA, Elema JD |title=Acrodermatitis chronica atrophicans: a light and electron microscopic study |journal=J. Cutan. Pathol. |volume=22 |issue=1 |pages=23–32 |year=1995 |month=February |pmid=7751475 |doi= |url=}}</ref> | *[[Microscopy|Light]] and [[Electron microscope|electron microscopic study]] of the [[skin]] [[biopsy]] shows degeneration of the [[Descemet's membrane|elastica]] and [[collagen]] fibers.<ref name="pmid7751475">{{cite journal |author=de Koning J, Tazelaar DJ, Hoogkamp-Korstanje JA, Elema JD |title=Acrodermatitis chronica atrophicans: a light and electron microscopic study |journal=J. Cutan. Pathol. |volume=22 |issue=1 |pages=23–32 |year=1995 |month=February |pmid=7751475 |doi= |url=}}</ref> | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Needs | [[Category:Needs review]] | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Dermatology]] | [[Category:Dermatology]] |
Revision as of 13:05, 2 June 2021
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anahita Deylamsalehi, M.D.[2] Raviteja Guddeti, M.B.B.S. [3]
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Differentiating Acrodermatitis chronica atrophicans from other Diseases |
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Overview
Pathophysiology
Pathogenesis
- This progressive skin process is due to the effect of chronic infection with the spirochete borrelia burgdorferi. Borrelia afzelii is the predominant pathophysiology, but may not be the exclusive, etiology of acrodermatitis chronica atrophicans.
- Borrelia garinii has also been detected in some patients.
Genetics
Associated Conditions
Conditions associated with [disease name] include:
Gross Pathology
On gross pathology, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].
Microscopic Pathology
- Light and electron microscopic study of the skin biopsy shows degeneration of the elastica and collagen fibers.[1]
References
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