Acute disseminated encephalomyelitis epidemiology and demographics: Difference between revisions
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
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Overview
Epidemiology and Demographics
Incidence
- The Incidence of Acute disseminated encephalomyelitis is about 1 in 125,000-250,000 people each year, in children younger than 10 years, despite the fact that it is a rare disorder.
- Each year, regional medical centers in the United States, the United Kingdom, and Australia see three to six instances.[1][2][3]
Prevalence
- The prevalence of Acute disseminated encephalomyelitis rises as one moves further away from the Equator.
Case-fatality rate/Mortality rate
- The mortality rate of retinoblastoma differs according to the stage of the disease as well as the geographic region.[4]
- In extraocular form of this disorder is reported to be greater than 50%.[5]
- However, tumors involving the optic disc superficially, are associated with 10% mortality rate.[6]
Age
- In youngsters, the usual age of onset is 3 to 7 years.
- Cases have also been reported in children between the ages of 10 and twenty.
- Adults between the ages of 18 and 82 are also affected.[7]
Gender
- Acute disseminated encephalomyelitis affects males more likely than females (male to female ratio of 1.3:1), and it happens more frequently in the winter and spring.
Race
- There is no racial predilection to the development of Acute disseminated encephalomyelitis and affects people all over the world.[8]
Region
- Its prevalence rises as one moves further away from the Equator, comparable to the geographic distribution of Multiple sclerosis.
References
- ↑ Dale RC, de Sousa C, Chong WK, Cox TC, Harding B, Neville BG (2000). "Acute disseminated encephalomyelitis, multiphasic disseminated encephalomyelitis and multiple sclerosis in children". Brain. 123 Pt 12: 2407–22. doi:10.1093/brain/123.12.2407. PMID 11099444.
- ↑ Hynson JL, Kornberg AJ, Coleman LT, Shield L, Harvey AS, Kean MJ (2001). "Clinical and neuroradiologic features of acute disseminated encephalomyelitis in children". Neurology. 56 (10): 1308–12. doi:10.1212/wnl.56.10.1308. PMID 11376179.
- ↑ Murthy SN, Faden HS, Cohen ME, Bakshi R (2002). "Acute disseminated encephalomyelitis in children". Pediatrics. 110 (2 Pt 1): e21. doi:10.1542/peds.110.2.e21. PMID 12165620.
- ↑ Dimaras, Helen; Kimani, Kahaki; Dimba, Elizabeth AO; Gronsdahl, Peggy; White, Abby; Chan, Helen SL; Gallie, Brenda L (2012). "Retinoblastoma". The Lancet. 379 (9824): 1436–1446. doi:10.1016/S0140-6736(11)61137-9. ISSN 0140-6736.
- ↑ Kim, J W; Kathpalia, V; Dunkel, I J; Wong, R K; Riedel, E; Abramson, D H (2008). "Orbital recurrence of retinoblastoma following enucleation". British Journal of Ophthalmology. 93 (4): 463–467. doi:10.1136/bjo.2008.138453. ISSN 0007-1161.
- ↑ Chévez-Barrios, Patricia; Eagle, Ralph C.; Marback, Eduardo F. (2015). "Histopathologic Features and Prognostic Factors": 167–183. doi:10.1007/978-3-662-43451-2_16.
- ↑ "StatPearls". 2021. PMID 28613684.
- ↑ Pellegrino P, Radice S, Clementi E (2014). "Geoepidemiology of acute disseminated encephalomyelitis". Epidemiology. 25 (6): 928–9. doi:10.1097/EDE.0000000000000176. PMID 25265138.