Acute disseminated encephalomyelitis epidemiology and demographics: Difference between revisions
Jump to navigation
Jump to search
| Line 20: | Line 20: | ||
===Case-fatality rate/Mortality rate=== | ===Case-fatality rate/Mortality rate=== | ||
* | *Although Acute disseminated encephalomyelitis is potentially lethal, the [https://www.wikidoc.org/index.php/Mortality_rate mortality rate] is low. | ||
*In extraocular form of this [https://www.wikidoc.org/index.php/Disorder disorder] is reported to be greater than 50%.<ref name="KimKathpalia2008">{{cite journal|last1=Kim|first1=J W|last2=Kathpalia|first2=V|last3=Dunkel|first3=I J|last4=Wong|first4=R K|last5=Riedel|first5=E|last6=Abramson|first6=D H|title=Orbital recurrence of retinoblastoma following enucleation|journal=British Journal of Ophthalmology|volume=93|issue=4|year=2008|pages=463–467|issn=0007-1161|doi=10.1136/bjo.2008.138453}}</ref> | *In extraocular form of this [https://www.wikidoc.org/index.php/Disorder disorder] is reported to be greater than 50%.<ref name="KimKathpalia2008">{{cite journal|last1=Kim|first1=J W|last2=Kathpalia|first2=V|last3=Dunkel|first3=I J|last4=Wong|first4=R K|last5=Riedel|first5=E|last6=Abramson|first6=D H|title=Orbital recurrence of retinoblastoma following enucleation|journal=British Journal of Ophthalmology|volume=93|issue=4|year=2008|pages=463–467|issn=0007-1161|doi=10.1136/bjo.2008.138453}}</ref> | ||
*However, [https://www.wikidoc.org/index.php/Tumors tumors] involving the [https://www.wikidoc.org/index.php/Optic_disc optic disc] superficially, are associated with 10% [https://www.wikidoc.org/index.php/Mortality_rate mortality rate].<ref name="Chévez-BarriosEagle2015">{{cite journal|last1=Chévez-Barrios|first1=Patricia|last2=Eagle|first2=Ralph C.|last3=Marback|first3=Eduardo F.|title=Histopathologic Features and Prognostic Factors|year=2015|pages=167–183|doi=10.1007/978-3-662-43451-2_16}}</ref> | *However, [https://www.wikidoc.org/index.php/Tumors tumors] involving the [https://www.wikidoc.org/index.php/Optic_disc optic disc] superficially, are associated with 10% [https://www.wikidoc.org/index.php/Mortality_rate mortality rate].<ref name="Chévez-BarriosEagle2015">{{cite journal|last1=Chévez-Barrios|first1=Patricia|last2=Eagle|first2=Ralph C.|last3=Marback|first3=Eduardo F.|title=Histopathologic Features and Prognostic Factors|year=2015|pages=167–183|doi=10.1007/978-3-662-43451-2_16}}</ref> | ||
*Majority are categorized as post-infectious CNS illness (viral or bacterial) being recorded in up to 50–75 percent of patients and the minority being after vaccination.<ref name="pmid27742816">{{cite journal| author=Yamaguchi Y, Torisu H, Kira R, Ishizaki Y, Sakai Y, Sanefuji M | display-authors=etal| title=A nationwide survey of pediatric acquired demyelinating syndromes in Japan. | journal=Neurology | year= 2016 | volume= 87 | issue= 19 | pages= 2006-2015 | pmid=27742816 | doi=10.1212/WNL.0000000000003318 | pmc=5109945 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27742816 }}</ref><ref name="pmid25761377">{{cite journal| author=Koelman DL, Mateen FJ| title=Acute disseminated encephalomyelitis: current controversies in diagnosis and outcome. | journal=J Neurol | year= 2015 | volume= 262 | issue= 9 | pages= 2013-24 | pmid=25761377 | doi=10.1007/s00415-015-7694-7 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25761377 }}</ref> | *Majority are categorized as post-infectious CNS illness (viral or bacterial) being recorded in up to 50–75 percent of patients and the minority being after vaccination.<ref name="pmid27742816">{{cite journal| author=Yamaguchi Y, Torisu H, Kira R, Ishizaki Y, Sakai Y, Sanefuji M | display-authors=etal| title=A nationwide survey of pediatric acquired demyelinating syndromes in Japan. | journal=Neurology | year= 2016 | volume= 87 | issue= 19 | pages= 2006-2015 | pmid=27742816 | doi=10.1212/WNL.0000000000003318 | pmc=5109945 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27742816 }}</ref><ref name="pmid25761377">{{cite journal| author=Koelman DL, Mateen FJ| title=Acute disseminated encephalomyelitis: current controversies in diagnosis and outcome. | journal=J Neurol | year= 2015 | volume= 262 | issue= 9 | pages= 2013-24 | pmid=25761377 | doi=10.1007/s00415-015-7694-7 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25761377 }}</ref><ref name="pmid26620160">{{cite journal| author=Berzero G, Cortese A, Ravaglia S, Marchioni E| title=Diagnosis and therapy of acute disseminated encephalomyelitis and its variants. | journal=Expert Rev Neurother | year= 2016 | volume= 16 | issue= 1 | pages= 83-101 | pmid=26620160 | doi=10.1586/14737175.2015.1126510 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26620160 }}</ref> | ||
===Age=== | ===Age=== | ||
Revision as of 22:50, 26 June 2021
|
Acute disseminated encephalomyelitis Microchapters |
|
Differentiating Acute disseminated encephalomyelitis from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Acute disseminated encephalomyelitis epidemiology and demographics On the Web |
|
American Roentgen Ray Society Images of Acute disseminated encephalomyelitis epidemiology and demographics |
|
FDA on Acute disseminated encephalomyelitis epidemiology and demographics |
|
CDC on Acute disseminated encephalomyelitis epidemiology and demographics |
|
Acute disseminated encephalomyelitis epidemiology and demographics in the news |
|
Blogs on Acute disseminated encephalomyelitis epidemiology and demographics |
|
Directions to Hospitals Treating Acute disseminated encephalomyelitis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Please help WikiDoc by adding content here. It's easy! Click here to learn about editing.
Overview
Epidemiology and Demographics
Incidence
- The Incidence of Acute disseminated encephalomyelitis is about 1 in 125,000-250,000 people each year, in children younger than 10 years, despite the fact that it is a rare disorder.
- Each year, regional medical centers in the United States, the United Kingdom, and Australia see three to six instances.[1][2][3]
Prevalence
- The prevalence of Acute disseminated encephalomyelitis rises as one moves further away from the Equator.
Case-fatality rate/Mortality rate
- Although Acute disseminated encephalomyelitis is potentially lethal, the mortality rate is low.
- In extraocular form of this disorder is reported to be greater than 50%.[4]
- However, tumors involving the optic disc superficially, are associated with 10% mortality rate.[5]
- Majority are categorized as post-infectious CNS illness (viral or bacterial) being recorded in up to 50–75 percent of patients and the minority being after vaccination.[6][7][8]
Age
- In youngsters, the usual age of onset is 3 to 7 years.
- Cases have also been reported in children between the ages of 10 and twenty.
- Adults between the ages of 18 and 82 are also affected.[9]
Gender
- Acute disseminated encephalomyelitis affects males more likely than females (male to female ratio of 1.3:1), and it happens more frequently in the winter and spring.
Race
- There is no racial predilection to the development of Acute disseminated encephalomyelitis and affects people all over the world.[10]
Region
- It affects people all over the world, comparable to the geographic distribution of Multiple sclerosis.
References
- ↑ Dale RC, de Sousa C, Chong WK, Cox TC, Harding B, Neville BG (2000). "Acute disseminated encephalomyelitis, multiphasic disseminated encephalomyelitis and multiple sclerosis in children". Brain. 123 Pt 12: 2407–22. doi:10.1093/brain/123.12.2407. PMID 11099444.
- ↑ Hynson JL, Kornberg AJ, Coleman LT, Shield L, Harvey AS, Kean MJ (2001). "Clinical and neuroradiologic features of acute disseminated encephalomyelitis in children". Neurology. 56 (10): 1308–12. doi:10.1212/wnl.56.10.1308. PMID 11376179.
- ↑ Murthy SN, Faden HS, Cohen ME, Bakshi R (2002). "Acute disseminated encephalomyelitis in children". Pediatrics. 110 (2 Pt 1): e21. doi:10.1542/peds.110.2.e21. PMID 12165620.
- ↑ Kim, J W; Kathpalia, V; Dunkel, I J; Wong, R K; Riedel, E; Abramson, D H (2008). "Orbital recurrence of retinoblastoma following enucleation". British Journal of Ophthalmology. 93 (4): 463–467. doi:10.1136/bjo.2008.138453. ISSN 0007-1161.
- ↑ Chévez-Barrios, Patricia; Eagle, Ralph C.; Marback, Eduardo F. (2015). "Histopathologic Features and Prognostic Factors": 167–183. doi:10.1007/978-3-662-43451-2_16.
- ↑ Yamaguchi Y, Torisu H, Kira R, Ishizaki Y, Sakai Y, Sanefuji M; et al. (2016). "A nationwide survey of pediatric acquired demyelinating syndromes in Japan". Neurology. 87 (19): 2006–2015. doi:10.1212/WNL.0000000000003318. PMC 5109945. PMID 27742816.
- ↑ Koelman DL, Mateen FJ (2015). "Acute disseminated encephalomyelitis: current controversies in diagnosis and outcome". J Neurol. 262 (9): 2013–24. doi:10.1007/s00415-015-7694-7. PMID 25761377.
- ↑ Berzero G, Cortese A, Ravaglia S, Marchioni E (2016). "Diagnosis and therapy of acute disseminated encephalomyelitis and its variants". Expert Rev Neurother. 16 (1): 83–101. doi:10.1586/14737175.2015.1126510. PMID 26620160.
- ↑ "StatPearls". 2021. PMID 28613684.
- ↑ Pellegrino P, Radice S, Clementi E (2014). "Geoepidemiology of acute disseminated encephalomyelitis". Epidemiology. 25 (6): 928–9. doi:10.1097/EDE.0000000000000176. PMID 25265138.