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| ==Indications== | | ==Indications== |
| ==2012 ACCF/AHA/HRS Focused Update of the 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities (DO NOT EDIT)<ref name="pmid23265327">{{cite journal |vauthors=Epstein AE, DiMarco JP, Ellenbogen KA, Estes NA, Freedman RA, Gettes LS, Gillinov AM, Gregoratos G, Hammill SC, Hayes DL, Hlatky MA, Newby LK, Page RL, Schoenfeld MH, Silka MJ, Stevenson LW, Sweeney MO, Tracy CM, Epstein AE, Darbar D, DiMarco JP, Dunbar SB, Estes NA, Ferguson TB, Hammill SC, Karasik PE, Link MS, Marine JE, Schoenfeld MH, Shanker AJ, Silka MJ, Stevenson LW, Stevenson WG, Varosy PD |title=2012 ACCF/AHA/HRS focused update incorporated into the ACCF/AHA/HRS 2008 guidelines for device-based therapy of cardiac rhythm abnormalities: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society |journal=J. Am. Coll. Cardiol. |volume=61 |issue=3 |pages=e6–75 |year=2013 |pmid=23265327 |doi=10.1016/j.jacc.2012.11.007 |url=}}</ref><ref name="pmid22975672">{{cite journal |author=Tracy CM, Epstein AE, Darbar D, Dimarco JP, Dunbar SB, Estes NA, Ferguson TB, Hammill SC, Karasik PE, Link MS, Marine JE, Schoenfeld MH, Shanker AJ, Silka MJ, Stevenson LW, Stevenson WG, Varosy PD |title=2012 ACCF/AHA/HRS Focused Update of the 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines |journal=Heart Rhythm |volume=9 |issue=10 |pages=1737–53 |year=2012 |month=October |pmid=22975672 |doi=10.1016/j.hrthm.2012.08.021 |url=http://linkinghub.elsevier.com/retrieve/pii/S1547-5271(12)00882-X |accessdate=2012-11-01}}</ref>==
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| ===CRT in Patients With Systolic Heart Failure (DO NOT EDIT)<ref name="pmid22975672">{{cite journal |author=Tracy CM, Epstein AE, Darbar D, Dimarco JP, Dunbar SB, Estes NA, Ferguson TB, Hammill SC, Karasik PE, Link MS, Marine JE, Schoenfeld MH, Shanker AJ, Silka MJ, Stevenson LW, Stevenson WG, Varosy PD |title=2012 ACCF/AHA/HRS Focused Update of the 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines |journal=Heart Rhythm |volume=9 |issue=10 |pages=1737–53 |year=2012 |month=October |pmid=22975672 |doi=10.1016/j.hrthm.2012.08.021 |url=http://linkinghub.elsevier.com/retrieve/pii/S1547-5271(12)00882-X |accessdate=2012-11-01}}</ref>===
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| | colspan="1" style="text-align:center; background:LightGreen"|[[ACC AHA guidelines classification scheme#Classification of Recommendations|Class I]]
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| | bgcolor="LightGreen"|<nowiki>"</nowiki>'''1.''' CRT is indicated for patients who have [[LVEF]] less than or equal to 35%, sinus rhythm, [[LBBB]] with a QRS duration greater than or equal to 150 ms, and [[NYHA]] class II, III, or ambulatory IV symptoms on GDMT. ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: A]] for NYHA class III/IV<ref name="pmid12063368">{{cite journal| author=Abraham WT, Fisher WG, Smith AL, Delurgio DB, Leon AR, Loh E et al.| title=Cardiac resynchronization in chronic heart failure. | journal=N Engl J Med | year= 2002 | volume= 346 | issue= 24 | pages= 1845-53 | pmid=12063368 | doi=10.1056/NEJMoa013168 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12063368 }} [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12418822 Review in: ACP J Club. 2002 Nov-Dec;137(3):82] </ref><ref name="pmid15152059">{{cite journal| author=Bristow MR, Saxon LA, Boehmer J, Krueger S, Kass DA, De Marco T et al.| title=Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. | journal=N Engl J Med | year= 2004 | volume= 350 | issue= 21 | pages= 2140-50 | pmid=15152059 | doi=10.1056/NEJMoa032423 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15152059 }} [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15518444 Review in: ACP J Club. 2004 Nov-Dec;141(3):60] </ref><ref name="pmid15753115">{{cite journal| author=Cleland JG, Daubert JC, Erdmann E, Freemantle N, Gras D, Kappenberger L et al.| title=The effect of cardiac resynchronization on morbidity and mortality in heart failure. | journal=N Engl J Med | year= 2005 | volume= 352 | issue= 15 | pages= 1539-49 | pmid=15753115 | doi=10.1056/NEJMoa050496 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15753115 }} [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16134903 Review in: ACP J Club. 2005 Sep-Oct;143(2):29] </ref><ref name="pmid19358937">{{cite journal| author=Hunt SA, Abraham WT, Chin MH, Feldman AM, Francis GS, Ganiats TG et al.| title=2009 Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines Developed in Collaboration With the International Society for Heart and Lung Transplantation. | journal=J Am Coll Cardiol | year= 2009 | volume= 53 | issue= 15 | pages= e1-e90 | pmid=19358937 | doi=10.1016/j.jacc.2008.11.013 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19358937 }} </ref>; [[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: B]] for NYHA class II<ref name="pmid20178156">{{cite journal| author=Kozłowski B| title=[Commentary to the article: Moss AJ, Hall WJ, Cannom DS, et al. Cardiac-resynchronization therapy for the prevention of heart-failure events. N Engl J Med 2009; 361: 1329-38]. | journal=Kardiol Pol | year= 2009 | volume= 67 | issue= 12 | pages= 1417-8 | pmid=20178156 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20178156 }} </ref><ref name="pmid21073365">{{cite journal| author=Tang AS, Wells GA, Talajic M, Arnold MO, Sheldon R, Connolly S et al.| title=Cardiac-resynchronization therapy for mild-to-moderate heart failure. | journal=N Engl J Med | year= 2010 | volume= 363 | issue= 25 | pages= 2385-95 | pmid=21073365 | doi=10.1056/NEJMoa1009540 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21073365 }} [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21436182 Review in: Evid Based Med. 2011 Oct;16(5):138-9] </ref>)''<nowiki>"</nowiki>
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| |colspan="1" style="text-align:center; background:LightCoral"|[[ACC AHA guidelines classification scheme#Classification of Recommendations|Class III]] (No Benefit)
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| |bgcolor="LightCoral"|<nowiki>"</nowiki>'''1.''' CRT is not recommended for patients with NYHA class I or II symptoms and non-LBBB pattern with QRS duration less than 150 ms.<ref name="pmid20178156">{{cite journal| author=Kozłowski B| title=[Commentary to the article: Moss AJ, Hall WJ, Cannom DS, et al. Cardiac-resynchronization therapy for the prevention of heart-failure events. N Engl J Med 2009; 361: 1329-38]. | journal=Kardiol Pol | year= 2009 | volume= 67 | issue= 12 | pages= 1417-8 | pmid=20178156 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20178156 }} </ref><ref name="pmid21073365">{{cite journal| author=Tang AS, Wells GA, Talajic M, Arnold MO, Sheldon R, Connolly S et al.| title=Cardiac-resynchronization therapy for mild-to-moderate heart failure. | journal=N Engl J Med | year= 2010 | volume= 363 | issue= 25 | pages= 2385-95 | pmid=21073365 | doi=10.1056/NEJMoa1009540 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21073365 }} [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21436182 Review in: Evid Based Med. 2011 Oct;16(5):138-9] </ref><ref name="pmid21890086">{{cite journal| author=Rickard J, Bassiouny M, Cronin EM, Martin DO, Varma N, Niebauer MJ et al.| title=Predictors of response to cardiac resynchronization therapy in patients with a non-left bundle branch block morphology. | journal=Am J Cardiol | year= 2011 | volume= 108 | issue= 11 | pages= 1576-80 | pmid=21890086 | doi=10.1016/j.amjcard.2011.07.017 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21890086 }} </ref> ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: B]])''<nowiki>"</nowiki>
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| |bgcolor="LightCoral"|<nowiki>"</nowiki>'''2.''' CRT is not indicated for patients whose comorbidities and/or frailty limit survival with good functional capacity to less than 1 year.<ref name="pmid19358937">{{cite journal| author=Hunt SA, Abraham WT, Chin MH, Feldman AM, Francis GS, Ganiats TG et al.| title=2009 Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines Developed in Collaboration With the International Society for Heart and Lung Transplantation. | journal=J Am Coll Cardiol | year= 2009 | volume= 53 | issue= 15 | pages= e1-e90 | pmid=19358937 | doi=10.1016/j.jacc.2008.11.013 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19358937 }} </ref> ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: C]])''<nowiki>"</nowiki>
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| | colspan="1" style="text-align:center; background:LemonChiffon"|[[ACC AHA guidelines classification scheme#Classification of Recommendations|Class IIa]]
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| |bgcolor="LemonChiffon"|<nowiki>"</nowiki>'''1.''' CRT can be useful for patients who have LVEF less than or equal to 35%, sinus rhythm, LBBB with a QRS duration 120 to 149 ms, and NYHA class II, III, or ambulatory IV symptoms on GDMT.<ref name="pmid12063368">{{cite journal| author=Abraham WT, Fisher WG, Smith AL, Delurgio DB, Leon AR, Loh E et al.| title=Cardiac resynchronization in chronic heart failure. | journal=N Engl J Med | year= 2002 | volume= 346 | issue= 24 | pages= 1845-53 | pmid=12063368 | doi=10.1056/NEJMoa013168 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12063368 }} [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12418822 Review in: ACP J Club. 2002 Nov-Dec;137(3):82] </ref><ref name="pmid15152059">{{cite journal| author=Bristow MR, Saxon LA, Boehmer J, Krueger S, Kass DA, De Marco T et al.| title=Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. | journal=N Engl J Med | year= 2004 | volume= 350 | issue= 21 | pages= 2140-50 | pmid=15152059 | doi=10.1056/NEJMoa032423 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15152059 }} [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15518444 Review in: ACP J Club. 2004 Nov-Dec;141(3):60] </ref><ref name="pmid15753115">{{cite journal| author=Cleland JG, Daubert JC, Erdmann E, Freemantle N, Gras D, Kappenberger L et al.| title=The effect of cardiac resynchronization on morbidity and mortality in heart failure. | journal=N Engl J Med | year= 2005 | volume= 352 | issue= 15 | pages= 1539-49 | pmid=15753115 | doi=10.1056/NEJMoa050496 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15753115 }} [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16134903 Review in: ACP J Club. 2005 Sep-Oct;143(2):29] </ref><ref name="pmid20178156">{{cite journal| author=Kozłowski B| title=[Commentary to the article: Moss AJ, Hall WJ, Cannom DS, et al. Cardiac-resynchronization therapy for the prevention of heart-failure events. N Engl J Med 2009; 361: 1329-38]. | journal=Kardiol Pol | year= 2009 | volume= 67 | issue= 12 | pages= 1417-8 | pmid=20178156 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20178156 }} </ref><ref name="pmid21073365">{{cite journal| author=Tang AS, Wells GA, Talajic M, Arnold MO, Sheldon R, Connolly S et al.| title=Cardiac-resynchronization therapy for mild-to-moderate heart failure. | journal=N Engl J Med | year= 2010 | volume= 363 | issue= 25 | pages= 2385-95 | pmid=21073365 | doi=10.1056/NEJMoa1009540 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21073365 }} [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21436182 Review in: Evid Based Med. 2011 Oct;16(5):138-9] </ref><ref name="pmid19038680">{{cite journal| author=Linde C, Abraham WT, Gold MR, St John Sutton M, Ghio S, Daubert C et al.| title=Randomized trial of cardiac resynchronization in mildly symptomatic heart failure patients and in asymptomatic patients with left ventricular dysfunction and previous heart failure symptoms. | journal=J Am Coll Cardiol | year= 2008 | volume= 52 | issue= 23 | pages= 1834-43 | pmid=19038680 | doi=10.1016/j.jacc.2008.08.027 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19038680 }} </ref> ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: B]])''<nowiki>"</nowiki>
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| |bgcolor="LemonChiffon"|<nowiki>"</nowiki>'''2.''' CRT can be useful for patients who have LVEF less than or equal to 35%, sinus rhythm, a non-LBBB pattern with a QRS duration greater than or equal to 150 ms, and NYHA class III/ambulatory class IV symptoms on GDMT.<ref name="pmid12063368">{{cite journal| author=Abraham WT, Fisher WG, Smith AL, Delurgio DB, Leon AR, Loh E et al.| title=Cardiac resynchronization in chronic heart failure. | journal=N Engl J Med | year= 2002 | volume= 346 | issue= 24 | pages= 1845-53 | pmid=12063368 | doi=10.1056/NEJMoa013168 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12063368 }} [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12418822 Review in: ACP J Club. 2002 Nov-Dec;137(3):82] </ref><ref name="pmid15152059">{{cite journal| author=Bristow MR, Saxon LA, Boehmer J, Krueger S, Kass DA, De Marco T et al.| title=Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. | journal=N Engl J Med | year= 2004 | volume= 350 | issue= 21 | pages= 2140-50 | pmid=15152059 | doi=10.1056/NEJMoa032423 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15152059 }} [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15518444 Review in: ACP J Club. 2004 Nov-Dec;141(3):60] </ref><ref name="pmid15753115">{{cite journal| author=Cleland JG, Daubert JC, Erdmann E, Freemantle N, Gras D, Kappenberger L et al.| title=The effect of cardiac resynchronization on morbidity and mortality in heart failure. | journal=N Engl J Med | year= 2005 | volume= 352 | issue= 15 | pages= 1539-49 | pmid=15753115 | doi=10.1056/NEJMoa050496 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15753115 }} [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16134903 Review in: ACP J Club. 2005 Sep-Oct;143(2):29] </ref><ref name="pmid21073365">{{cite journal| author=Tang AS, Wells GA, Talajic M, Arnold MO, Sheldon R, Connolly S et al.| title=Cardiac-resynchronization therapy for mild-to-moderate heart failure. | journal=N Engl J Med | year= 2010 | volume= 363 | issue= 25 | pages= 2385-95 | pmid=21073365 | doi=10.1056/NEJMoa1009540 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21073365 }} [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21436182 Review in: Evid Based Med. 2011 Oct;16(5):138-9] </ref> ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: A]])''<nowiki>"</nowiki>
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| |bgcolor="LemonChiffon"|<nowiki>"</nowiki>'''3.''' CRT can be useful in patients with [[atrial fibrillation]] and LVEF less than or equal to 35% on GDMT if a) the patient requires [[ventricular pacing]] or otherwise meets CRT criteria and b) [[AV nodal ablation]] or pharmacologic rate control will allow near 100% ventricular pacing with CRT.<ref name="pmid15618036">{{cite journal| author=Brignole M, Gammage M, Puggioni E, Alboni P, Raviele A, Sutton R et al.| title=Comparative assessment of right, left, and biventricular pacing in patients with permanent atrial fibrillation. | journal=Eur Heart J | year= 2005 | volume= 26 | issue= 7 | pages= 712-22 | pmid=15618036 | doi=10.1093/eurheartj/ehi069 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15618036 }} </ref><ref name="pmid21606084">{{cite journal| author=Brignole M, Botto G, Mont L, Iacopino S, De Marchi G, Oddone D et al.| title=Cardiac resynchronization therapy in patients undergoing atrioventricular junction ablation for permanent atrial fibrillation: a randomized trial. | journal=Eur Heart J | year= 2011 | volume= 32 | issue= 19 | pages= 2420-9 | pmid=21606084 | doi=10.1093/eurheartj/ehr162 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21606084 }} </ref><ref name="pmid16302897">{{cite journal| author=Doshi RN, Daoud EG, Fellows C, Turk K, Duran A, Hamdan MH et al.| title=Left ventricular-based cardiac stimulation post AV nodal ablation evaluation (the PAVE study). | journal=J Cardiovasc Electrophysiol | year= 2005 | volume= 16 | issue= 11 | pages= 1160-5 | pmid=16302897 | doi=10.1111/j.1540-8167.2005.50062.x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16302897 }} </ref><ref name="pmid16904542">{{cite journal| author=Gasparini M, Auricchio A, Regoli F, Fantoni C, Kawabata M, Galimberti P et al.| title=Four-year efficacy of cardiac resynchronization therapy on exercise tolerance and disease progression: the importance of performing atrioventricular junction ablation in patients with atrial fibrillation. | journal=J Am Coll Cardiol | year= 2006 | volume= 48 | issue= 4 | pages= 734-43 | pmid=16904542 | doi=10.1016/j.jacc.2006.03.056 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16904542 }} </ref><ref name="pmid21338711">{{cite journal| author=Wilton SB, Leung AA, Ghali WA, Faris P, Exner DV| title=Outcomes of cardiac resynchronization therapy in patients with versus those without atrial fibrillation: a systematic review and meta-analysis. | journal=Heart Rhythm | year= 2011 | volume= 8 | issue= 7 | pages= 1088-94 | pmid=21338711 | doi=10.1016/j.hrthm.2011.02.014 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21338711 }} </ref><ref name="pmid18926327">{{cite journal| author=Upadhyay GA, Choudhry NK, Auricchio A, Ruskin J, Singh JP| title=Cardiac resynchronization in patients with atrial fibrillation: a meta-analysis of prospective cohort studies. | journal=J Am Coll Cardiol | year= 2008 | volume= 52 | issue= 15 | pages= 1239-46 | pmid=18926327 | doi=10.1016/j.jacc.2008.06.043 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18926327 }} </ref> ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: B]])''<nowiki>"</nowiki>
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| |bgcolor="LemonChiffon"|<nowiki>"</nowiki>'''4.''' CRT can be useful for patients on GDMT who have LVEF less than or equal to 35% and are undergoing new or replacement device placement with anticipated requirement for significant (>40%) ventricular pacing.<ref name="pmid16302897">{{cite journal| author=Doshi RN, Daoud EG, Fellows C, Turk K, Duran A, Hamdan MH et al.| title=Left ventricular-based cardiac stimulation post AV nodal ablation evaluation (the PAVE study). | journal=J Cardiovasc Electrophysiol | year= 2005 | volume= 16 | issue= 11 | pages= 1160-5 | pmid=16302897 | doi=10.1111/j.1540-8167.2005.50062.x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16302897 }} </ref><ref name="pmid12495391">{{cite journal| author=Wilkoff BL, Cook JR, Epstein AE, Greene HL, Hallstrom AP, Hsia H et al.| title=Dual-chamber pacing or ventricular backup pacing in patients with an implantable defibrillator: the Dual Chamber and VVI Implantable Defibrillator (DAVID) Trial. | journal=JAMA | year= 2002 | volume= 288 | issue= 24 | pages= 3115-23 | pmid=12495391 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12495391 }} </ref><ref name="pmid21332868">{{cite journal| author=Adelstein E, Schwartzman D, Gorcsan J, Saba S| title=Predicting hyperresponse among pacemaker-dependent nonischemic cardiomyopathy patients upgraded to cardiac resynchronization. | journal=J Cardiovasc Electrophysiol | year= 2011 | volume= 22 | issue= 8 | pages= 905-11 | pmid=21332868 | doi=10.1111/j.1540-8167.2011.02018.x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21332868 }} </ref><ref name="pmid19406272">{{cite journal| author=Vatankulu MA, Goktekin O, Kaya MG, Ayhan S, Kucukdurmaz Z, Sutton R et al.| title=Effect of long-term resynchronization therapy on left ventricular remodeling in pacemaker patients upgraded to biventricular devices. | journal=Am J Cardiol | year= 2009 | volume= 103 | issue= 9 | pages= 1280-4 | pmid=19406272 | doi=10.1016/j.amjcard.2009.01.023 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19406272 }} </ref> ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: C]])''<nowiki>"</nowiki>
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| {|class="wikitable"
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| | colspan="1" style="text-align:center; background:LemonChiffon"|[[ACC AHA guidelines classification scheme#Classification of Recommendations|Class IIb]]
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| |bgcolor="LemonChiffon"|<nowiki>"</nowiki>'''1.''' CRT may be considered for patients who have LVEF less than or equal to 30%, ischemic etiology of heart failure, sinus rhythm, LBBB with a QRS duration of greater than or equal to 150 ms, and NYHA class I symptoms on GDMT.<ref name="pmid20178156">{{cite journal| author=Kozłowski B| title=[Commentary to the article: Moss AJ, Hall WJ, Cannom DS, et al. Cardiac-resynchronization therapy for the prevention of heart-failure events. N Engl J Med 2009; 361: 1329-38]. | journal=Kardiol Pol | year= 2009 | volume= 67 | issue= 12 | pages= 1417-8 | pmid=20178156 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20178156 }} </ref><ref name="pmid21073365">{{cite journal| author=Tang AS, Wells GA, Talajic M, Arnold MO, Sheldon R, Connolly S et al.| title=Cardiac-resynchronization therapy for mild-to-moderate heart failure. | journal=N Engl J Med | year= 2010 | volume= 363 | issue= 25 | pages= 2385-95 | pmid=21073365 | doi=10.1056/NEJMoa1009540 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21073365 }} [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21436182 Review in: Evid Based Med. 2011 Oct;16(5):138-9] </ref> ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: C]])''<nowiki>"</nowiki>
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| |bgcolor="LemonChiffon"|<nowiki>"</nowiki>'''2.''' CRT may be considered for patients who have LVEF less than or equal to 35%, sinus rhythm, a non-LBBB pattern with QRS duration 120 to 149 ms, and NYHA class III/ambulatory class IV on GDMT.<ref name="pmid21073365">{{cite journal| author=Tang AS, Wells GA, Talajic M, Arnold MO, Sheldon R, Connolly S et al.| title=Cardiac-resynchronization therapy for mild-to-moderate heart failure. | journal=N Engl J Med | year= 2010 | volume= 363 | issue= 25 | pages= 2385-95 | pmid=21073365 | doi=10.1056/NEJMoa1009540 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21073365 }} [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21436182 Review in: Evid Based Med. 2011 Oct;16(5):138-9] </ref><ref name="pmid21890086">{{cite journal| author=Rickard J, Bassiouny M, Cronin EM, Martin DO, Varma N, Niebauer MJ et al.| title=Predictors of response to cardiac resynchronization therapy in patients with a non-left bundle branch block morphology. | journal=Am J Cardiol | year= 2011 | volume= 108 | issue= 11 | pages= 1576-80 | pmid=21890086 | doi=10.1016/j.amjcard.2011.07.017 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21890086 }} </ref> ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: B]])''<nowiki>"</nowiki>
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| |bgcolor="LemonChiffon"|<nowiki>"</nowiki>'''3.''' CRT may be considered for patients who have LVEF less than or equal to 35%, sinus rhythm, a non-LBBB pattern with a QRS duration greater than or equal to 150 ms, and NYHA class II symptoms on GDMT.<ref name="pmid20178156">{{cite journal| author=Kozłowski B| title=[Commentary to the article: Moss AJ, Hall WJ, Cannom DS, et al. Cardiac-resynchronization therapy for the prevention of heart-failure events. N Engl J Med 2009; 361: 1329-38]. | journal=Kardiol Pol | year= 2009 | volume= 67 | issue= 12 | pages= 1417-8 | pmid=20178156 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20178156 }} </ref><ref name="pmid21073365">{{cite journal| author=Tang AS, Wells GA, Talajic M, Arnold MO, Sheldon R, Connolly S et al.| title=Cardiac-resynchronization therapy for mild-to-moderate heart failure. | journal=N Engl J Med | year= 2010 | volume= 363 | issue= 25 | pages= 2385-95 | pmid=21073365 | doi=10.1056/NEJMoa1009540 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21073365 }} [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21436182 Review in: Evid Based Med. 2011 Oct;16(5):138-9] </ref> ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: B]])''<nowiki>"</nowiki>
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| ==References== | | ==References== |
| {{Reflist|2}} | | {{Reflist|2}} |