Eczema causes: Difference between revisions
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==Causes== | ==Causes== | ||
*Damage from the [[Enzyme|enzymatic]] activity of [[allergens]] is usually prevented by the body's own [[protease inhibitor]]s, such as, ''[[LEKTI]]'', produced from the gene ''[[SPINK5]]''. | *Damage from the [[Enzyme|enzymatic]] activity of [[allergens]] is usually prevented by the body's own [[protease inhibitor]]s, such as, ''[[LEKTI]]'', produced from the gene ''[[SPINK5]]''. | ||
*Lack of [[filaggrin]] [[gene]] causes [[dry skin]]. | *Lack of [[filaggrin]] [[gene]] causes [[dry skin]]. <ref name="pmid16550169">{{cite journal| author=Palmer CN, Irvine AD, Terron-Kwiatkowski A, Zhao Y, Liao H, Lee SP | display-authors=etal| title=Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis. | journal=Nat Genet | year= 2006 | volume= 38 | issue= 4 | pages= 441-6 | pmid=16550169 | doi=10.1038/ng1767 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16550169 }} </ref> | ||
== Common Medications with Eczema as the Adverse Drug Effect == | == Common Medications with Eczema as the Adverse Drug Effect == | ||
Revision as of 19:12, 10 June 2022
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Eczema Microchapters |
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Treatment |
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Case Studies |
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Eczema On the Web |
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American Roentgen Ray Society Images of Eczema |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Edzel Lorraine Co, D.M.D., M.D.
Overview
Eczema could be due to a genetic problem, or a result of the adverse effect of certain medication.
Causes
- Damage from the enzymatic activity of allergens is usually prevented by the body's own protease inhibitors, such as, LEKTI, produced from the gene SPINK5.
- Lack of filaggrin gene causes dry skin. [1]
Common Medications with Eczema as the Adverse Drug Effect
- Below is a list of commonly prescribed medications with eczema as the common adverse drug effect (Table 1).
| Medication |
|---|
| Cidofovir |
| Flurbiprofen |
| Olaparib |
| Siltuximab |
| Sorafenib |
| Tiagabine |
References
- ↑ Palmer CN, Irvine AD, Terron-Kwiatkowski A, Zhao Y, Liao H, Lee SP; et al. (2006). "Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis". Nat Genet. 38 (4): 441–6. doi:10.1038/ng1767. PMID 16550169.