Eczema causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Edzel Lorraine Co, D.M.D., M.D.

Overview

The etiology of eczema is multifactorial and complex. This involves aberrations in genetic component, adverse effect of certain medication and some environmental factors.

Causes

• Damage from the enzymatic activity of allergens is usually prevented by the body's own protease inhibitors, such as, LEKTI, produced from the gene SPINK5.
• Lack of filaggrin gene causes dry skin.

Common Medications with Eczema as the Adverse Drug Effect

• Below is a list of commonly prescribed medications with eczema as the common adverse drug effect (Table 1).

Table 1. More Common types of Eczema.

Medication
Cidofovir
Flurbiprofen
Olaparib
Siltuximab
Sorafenib
Tiagabine