Laron syndrome (patient information)

For the WikiDoc page for this topic, click here

WikiDoc Resources for Laron syndrome (patient information)
Articles
Most recent articles on Laron syndrome (patient information) Most cited articles on Laron syndrome (patient information) Review articles on Laron syndrome (patient information) Articles on Laron syndrome (patient information) in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Laron syndrome (patient information) Images of Laron syndrome (patient information) Photos of Laron syndrome (patient information) Podcasts & MP3s on Laron syndrome (patient information) Videos on Laron syndrome (patient information)
Evidence Based Medicine
Cochrane Collaboration on Laron syndrome (patient information) Bandolier on Laron syndrome (patient information) TRIP on Laron syndrome (patient information)
Clinical Trials
Ongoing Trials on Laron syndrome (patient information) at Clinical Trials.gov Trial results on Laron syndrome (patient information) Clinical Trials on Laron syndrome (patient information) at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Laron syndrome (patient information) NICE Guidance on Laron syndrome (patient information) NHS PRODIGY Guidance FDA on Laron syndrome (patient information) CDC on Laron syndrome (patient information)
Books
Books on Laron syndrome (patient information)
News
Laron syndrome (patient information) in the news Be alerted to news on Laron syndrome (patient information) News trends on Laron syndrome (patient information)
Commentary
Blogs on Laron syndrome (patient information)
Definitions
Definitions of Laron syndrome (patient information)
Patient Resources / Community
Patient resources on Laron syndrome (patient information) Discussion groups on Laron syndrome (patient information) Patient Handouts on Laron syndrome (patient information) Directions to Hospitals Treating Laron syndrome (patient information) Risk calculators and risk factors for Laron syndrome (patient information)
Healthcare Provider Resources
Symptoms of Laron syndrome (patient information) Causes & Risk Factors for Laron syndrome (patient information) Diagnostic studies for Laron syndrome (patient information) Treatment of Laron syndrome (patient information)
Continuing Medical Education (CME)
CME Programs on Laron syndrome (patient information)
International
Laron syndrome (patient information) en Espanol Laron syndrome (patient information) en Francais
Business
Laron syndrome (patient information) in the Marketplace Patents on Laron syndrome (patient information)
Experimental / Informatics
List of terms related to Laron syndrome (patient information)

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Jinhui Wu, MD

Please Join in Editing This Page and Apply to be an Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [2] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

How do I know if I have Laron syndrome and what are the symptoms of Laron syndrome?

The principal feature of Laron syndrome is abnormally short stature

• Short hands and short feet
• Unusual facies: Prominent forehead, deep-set eyes, blue sclera, saddle nose and depressed nose bridge
• Proportionally larger head and abnormal skull growth
• High-pitched voice
• Reduced or normal intelligence
• Delayed bone age
• Delayed menstruation onset in girls
• Small penis in boys
• Delayed sexual development
• Childlike proportions in adults
• Obesity

Who is at risk for Laron syndrome?

Clinical investigations have demonstrated that the cause of Laron syndrome is associated with gene mutations in growth hormone receptor.

How to know you have Laron syndrome?

• Blood hormone tests, including the level of growth hormone (GH), insulinlike growth factor-1 (IGF-I), insulinlike growth factor binding protein-3 (IGFBP-3), basal GH, and GH binding protein (GHBP). Other tests invlove an IGF/IGFBP-3 generation test and provocative GH test. The doctor will manage the test and explain the results to you.
• Blood glucose and lipid test: It may show hypoglycemia and hypercholesterolemia in patients with Laron syndrome.
• A bone age test: For children suspect Laron syndrome, dual energy x-ray absorptiometry (DEXA) scans can be used to determine bone age.
• Cranial MRI: The goal of cranial MRI is to rule out growth hormone deficiency caused by other damage, such as tumor or injure in hypothalamus and pituitary glands.

Diseases with similar symptoms

• Intrauterine growth retardation
• Constitutional delay of growth
• Idiopathic short stature
• Nutritional growth retardation
• Psychosocial short stature

Where to find medical care for Laron syndrome?

Directions to Hospitals Treating Laron syndrome

Copyleft Sources

http://emedicine.medscape.com/article/922902-overview

http://www.wrongdiagnosis.com/l/laron_syndrome/intro.htm