Manchester score: Difference between revisions
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'''Manchester score''' is an indicator of [[prognosis]] in small cell [[lung cancer]].<ref name="Cerny">{{cite journal | last =Cerny | first =T | authorlink = | coauthors =Blair V, Anderson H et al. | title =Pretreatment prognostic factors and scoring system in 407 small-cell lung cancer patients | journal =International Journal of Cancer | volume =39 | issue =2 | pages =146-149 | publisher = | date =1987 | url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=3026969&query_hl=2&itool=pubmed_DocSum | doi = | id = | accessdate = }}</ref><ref name="Kawahara">{{cite journal | last =Kawahara | first =Masaaki | authorlink = | coauthors =Masahiro Fukuoka, Nagahiro Saijo et al. | title =Prognostic factors and prognostic staging system for small cell lung cancer | journal =Japanese Journal of Clinical Oncology | volume =27 | issue =3 | pages =158-165 | publisher =Oxford University Press | date =1996 | url =http://jjco.oxfordjournals.org/cgi/content/full/27/3/158 | doi = | id =ISSN: 0368-2811 | accessdate = }}</ref> It is calculated from a number of physical and biochemical markers. | '''Manchester score''' is an indicator of [[prognosis]] in small cell [[lung cancer]].<ref name="Cerny">{{cite journal | last =Cerny | first =T | authorlink = | coauthors =Blair V, Anderson H et al. | title =Pretreatment prognostic factors and scoring system in 407 small-cell lung cancer patients | journal =International Journal of Cancer | volume =39 | issue =2 | pages =146-149 | publisher = | date =1987 | url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=3026969&query_hl=2&itool=pubmed_DocSum | doi = | id = | accessdate = }}</ref><ref name="Kawahara">{{cite journal | last =Kawahara | first =Masaaki | authorlink = | coauthors =Masahiro Fukuoka, Nagahiro Saijo et al. | title =Prognostic factors and prognostic staging system for small cell lung cancer | journal =Japanese Journal of Clinical Oncology | volume =27 | issue =3 | pages =158-165 | publisher =Oxford University Press | date =1996 | url =http://jjco.oxfordjournals.org/cgi/content/full/27/3/158 | doi = | id =ISSN: 0368-2811 | accessdate = }}</ref> It is calculated from a number of physical and biochemical markers. | ||
Revision as of 13:57, 26 September 2011
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Manchester score is an indicator of prognosis in small cell lung cancer.[1][2] It is calculated from a number of physical and biochemical markers.
A patient with small cell lung cancer scores one point for each of the following: -
- Serum lactate dehydrogenase exceeds the upper limit of the reference range.
- Serum sodium concentration less than 132 mmol/l.
- Serum alkaline phosphatase over one-and-a-half times the upper limit of the reference range.
- Serum bicarbonate less than 24.
- Karnofsky performance status less than 60.
- Extensive stage disease.
Prognosis
| Manchester score | Prognostic group | Two year survival (%) |
|---|---|---|
| 0-1 | Good | 16.2 |
| 2-3 | Medium | 2.5 |
| 4 or more | Poor | 0 |
References
- ↑ Cerny, T (1987). "Pretreatment prognostic factors and scoring system in 407 small-cell lung cancer patients". International Journal of Cancer. 39 (2): 146–149. Unknown parameter
|coauthors=ignored (help) - ↑ Kawahara, Masaaki (1996). "Prognostic factors and prognostic staging system for small cell lung cancer". Japanese Journal of Clinical Oncology. Oxford University Press. 27 (3): 158–165. ISSN: 0368-2811. Unknown parameter
|coauthors=ignored (help) - ↑ Maestu, I (Jun 1997). "Pretreatment prognostic factors for survival in small-cell lung cancer: a new prognostic index and validation of three known prognostic indices on 341 patients". Annals of Oncology. 8 (6): 547–553. Unknown parameter
|coauthors=ignored (help)