Edoxaban: Difference between revisions

	WikiDoc Resources for Edoxaban
Articles
Most recent articles on Edoxaban Most cited articles on Edoxaban Review articles on Edoxaban Articles on Edoxaban in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Edoxaban Images of Edoxaban Photos of Edoxaban Podcasts & MP3s on Edoxaban Videos on Edoxaban
Evidence Based Medicine
Cochrane Collaboration on Edoxaban Bandolier on Edoxaban TRIP on Edoxaban
Clinical Trials
Ongoing Trials on Edoxaban at Clinical Trials.gov Trial results on Edoxaban Clinical Trials on Edoxaban at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Edoxaban NICE Guidance on Edoxaban NHS PRODIGY Guidance FDA on Edoxaban CDC on Edoxaban
Books
Books on Edoxaban
News
Edoxaban in the news Be alerted to news on Edoxaban News trends on Edoxaban
Commentary
Blogs on Edoxaban
Definitions
Definitions of Edoxaban
Patient Resources / Community
Patient resources on Edoxaban Discussion groups on Edoxaban Patient Handouts on Edoxaban Directions to Hospitals Treating Edoxaban Risk calculators and risk factors for Edoxaban
Healthcare Provider Resources
Symptoms of Edoxaban Causes & Risk Factors for Edoxaban Diagnostic studies for Edoxaban Treatment of Edoxaban
Continuing Medical Education (CME)
CME Programs on Edoxaban
International
Edoxaban en Espanol Edoxaban en Francais
Business
Edoxaban in the Marketplace Patents on Edoxaban
Experimental / Informatics
List of terms related to Edoxaban

Edoxaban
	File:Edoxaban skeletal.svg
Clinical data
ATC code	none;
Identifiers
	IUPAC name N'-(5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide;
CAS Number	912273-65-5;
PubChem CID	25022378;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C24H30ClN7O4S
Molar mass	548.056 g/mol

VisualWikitext

Revision as of 18:52, 27 September 2011

Edoxaban (INN, codenamed DU-176b) is an anticoagulant drug which acts as a direct factor Xa inhibitor. It is being developed by Daiichi Sankyo. In animal studies, edoxaban is potent, selective for factor Xa and has good oral bioavailability,^[1] but it has not been approved for use in humans.^[2]

Several Phase II clinical trials have been conducted, for example for thromboprophylaxis after total hip replacement^[3] and for stroke prevention in patients with atrial fibrillation^[4].

References

↑ Furugohri T, Isobe K, Honda Y, Kamisato-Matsumoto C, Sugiyama N, Nagahara T, Morishima Y, Shibano T (2008). "DU-176b, a potent and orally active factor Xa inhibitor: in vitro and in vivo pharmacological profiles". Journal of Thrombosis and Haemostasis : JTH. 6 (9): 1542–9. doi:10.1111/j.1538-7836.2008.03064.x. PMID 18624979. Unknown parameter |month= ignored (help)
↑ Sobieraj-Teague M, O'Donnell M, Eikelboom J (2009). "New anticoagulants for atrial fibrillation". Seminars in Thrombosis and Hemostasis. 35 (5): 515–24. doi:10.1055/s-0029-1234147. PMID 19739042. Unknown parameter |month= ignored (help)
↑ PMID 20589317
↑ PMID 20694273

Template:WH Template:WS

[pmid18624979-1] Furugohri T, Isobe K, Honda Y, Kamisato-Matsumoto C, Sugiyama N, Nagahara T, Morishima Y, Shibano T (2008). "DU-176b, a potent and orally active factor Xa inhibitor: in vitro and in vivo pharmacological profiles". Journal of Thrombosis and Haemostasis : JTH. 6 (9): 1542–9. doi:10.1111/j.1538-7836.2008.03064.x. PMID 18624979. Unknown parameter |month= ignored (help)

[pmid19739042-2] Sobieraj-Teague M, O'Donnell M, Eikelboom J (2009). "New anticoagulants for atrial fibrillation". Seminars in Thrombosis and Hemostasis. 35 (5): 515–24. doi:10.1055/s-0029-1234147. PMID 19739042. Unknown parameter |month= ignored (help)

[3] PMID 20589317

[4] PMID 20694273

[1]

[2]

[3]

[4]

Revision as of 17:12, 19 November 2010 (view source) C Michael Gibson (talk \| contribs) (New page: {{drugbox \| IUPAC_name = ''N'''-(5-chloropyridin-2-yl)-''N''-[(1''S'',2''R'',4''S'')-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4''H''-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)am...)	Revision as of 18:52, 27 September 2011 (view source) WikiBot (talk \| contribs) m (Protected "Edoxaban": Protecting pages from unwanted edits ([edit=sysop] (indefinite) [move=sysop] (indefinite))) Newer edit →
(No difference)

Clinical data
File:Edoxaban skeletal.svg
ATC code	none
Identifiers
IUPAC name N'-(5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide
CAS Number	912273-65-5
PubChem CID	25022378
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₂₄H₃₀ClN₇O₄S
Molar mass	548.056 g/mol

Edoxaban: Difference between revisions

Revision as of 18:52, 27 September 2011

References

Navigation menu