Guillain-Barré syndrome epidemiology and demographics: Difference between revisions
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===USA=== | ===USA=== | ||
* It is the commonest cause of '''acute, flaccid''' paralysis in USA. | * It is the commonest cause of '''acute, flaccid''' paralysis in USA. | ||
* Incidence- 1.2 - 3 / 100,000 persons | * Incidence- 1.2 - 3 / 100,000 persons <ref name="pmid1741839">{{cite journal |author=Day N |title=AIDS and insurer discretion |journal=[[Ohio Medicine : Journal of the Ohio State Medical Association]] |volume=87 |issue=5 |pages=226 |year=1991 |month=May |pmid=1741839 |doi= |url= |accessdate=2012-02-17}}</ref> | ||
===International=== | ===International=== | ||
* It has been reported all over the world. | * It has been reported all over the world. | ||
Revision as of 22:07, 17 February 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Priyamvada Singh, MBBS [2]
Overview
Guillain-Barré syndrome (GBS) is an acute, autoimmune, polyradiculoneuropathy affecting the peripheral nervous system, usually triggered by an acute infectious process. The incidence is approximately 1.2 - 3 / 100,000 persons per year across the world. It is commoner in males compared to female and has two peaks (15-35 years and 50-75 years). Incidence is similar across different races.
Epidemiology and demographics
USA
- It is the commonest cause of acute, flaccid paralysis in USA.
- Incidence- 1.2 - 3 / 100,000 persons [1]
International
- It has been reported all over the world.
- The incidence is around 1.5 - 3 / 100,000 persons
- The antecedence of Clostridum jejuni is commoner in Japan and other Asian countries. Whereas, in American continents and European nation an antecedence of cytomegalovirus is common.
Age
- Incidence increases with age.
- Bimodal distribution - First peak during 15 - 35 yrs and second during old age.
- New-borns and infants have the least risks of development of GBS
Race
- Incidence is similar across different races.
Gender
- It occurs more commonly in males compared to females. Male to female ratio 1.5:1
- The incidence has been found to increase post-partum and decreases during pregnancy