Guillain-Barré syndrome risk factors: Difference between revisions
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*It is important to keep in mind that severe illness and death are associated with influenza, and vaccination is the best way to prevent influenza infection and its complications. | *It is important to keep in mind that severe illness and death are associated with influenza, and vaccination is the best way to prevent influenza infection and its complications. | ||
==External link== | ==External link== | ||
[ | [http://www.cdc.gov/flu/protect/vaccine/guillainbarre.htm] | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 01:05, 21 February 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Priyamvada Singh, MBBS [2]
Overview
Guillain-Barré syndrome (GBS) is an acute, autoimmune, polyradiculoneuropathy affecting the peripheral nervous system, usually triggered by an acute infectious process. Anyone can develop GBS; however, it is more common among older adults. The incidence of GBS increases with age, and people older than 50 years are at greatest risk for developing GBS. The Institute of Medicine (IOM) conducted a thorough scientific review of this issue in 2003 and concluded that people who received the 1976 swine influenza vaccine had an increased risk for developing GBS.
Risk factors
- Anyone can develop Guillain-Barré syndrome; however, it is more common among older adults. The incidence of GBS increases with age, and people older than 50 years are at greatest risk for developing GBS.
- In 1976 there was a small increased risk of GBS following vaccination with an influenza vaccine made to protect against a swine flu virus.
- The increased risk was approximately 1 additional case of GBS per 100,000 people who got the swine flu vaccine.
- The Institute of Medicine (IOM) conducted a thorough scientific review of this issue in 2003 and concluded that people who received the 1976 swine influenza vaccine had an increased risk for developing GBS.
- Scientists have multiple theories on why this increased risk may have occurred, but the exact reason for this association remains unknown.
- It is important to keep in mind that severe illness and death are associated with influenza, and vaccination is the best way to prevent influenza infection and its complications.