Ebola: Difference between revisions

	Ebola Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Ebola from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Algorithm for the Evaluation of the Returned Traveler
Emergency Department Evaluation
Case Definition
History and Symptoms
Physical Examination
Laboratory Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Hospital Preparedness
Checklists
Air Medical Transport
Monitoring and Movement Following Exposure
Primary Prevention
Future or Investigational Therapies
Postmortem Care
Postmortem Care
Case Studies
Case #1
Ebola On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Ebola All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Ebola
CDC on Ebola
Ebola in the news
Blogs on Ebola
Directions to Hospitals Treating ebola
Risk calculators and risk factors for Ebola

	Ebola;
ICD-10	A98.4
ICD-9	065.8
DiseasesDB	18043
MedlinePlus	001339
MeSH	C02.782.417.415

style="background:#Template:Taxobox colour;"\|Ebola virus
	;
style="background:#Template:Taxobox colour;" \| Virus classification
Group:	Group V ((-)ssRNA)
Order:	Mononegavirales;
Family:	Filovirus;
Genus:	Ebolavirus;
Type species
	Zaïre Ebolavirus;
Species
	Reston Ebolavirus; Sudan Ebolavirus; Ivory Coast Ebolavirus; Bundibugyo Ebolavirus

← Older edit Newer edit →

VisualWikitext

Revision as of 16:00, 5 April 2012

For patient information click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Classification

Historical Perspective

Pathophysiology

Epidemiology & Demographics

Risk Factors

Causes

Differentiating Ebola

Natural history, Complications, and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory tests | Case Studies

Treatment

Medical therapy | Primary prevention | Secondary prevention | Financial costs | Future therapies

References

External links

Overviews

Database entry on genus Ebolavirus - ICTVdB
Ebola Virus Haemorrhagic Fever - Proceedings of an International Colloquium on Ebola Virus Infection and Other Haemorrhagic Fevers held in Antwerp, Belgium, 6-8 December, 1977
Questions and Answers about Ebola Hemorrhagic Fever - Center for Disease Control (CDC), retrieved 10 July 2006
WHO Factsheet - retrieved 10 July 2006
Vaccine Research Center (VRC) - Information concerning Ebola vaccine research studies

Outbreaks

Ebola outbreak in Congo - CBC News, 12 September 2007. Retrieved 2007-09-13.
Ebola 'kills over 5,000 gorillas' - BBC News, 8 December 2006. Retrieved 2006-12-08.
History of Ebola Outbreaks - Centers for Disease Control Special Pathogens Branch, retrieved 2006-07-10.
Infection Control for Viral Hemorrhagic Fevers in the African Health Care Setting - Center for Disease Control and Prevention, Atlanta, December 1998.
Filovirus Global Symposium - Filomeeting 2008

Life Cycle

Biomarker Database - information on Ebola

Infectivity

U.S. Army Medical Research Institute of Infectious Diseases: Gene-Specific Ebola Therapies Protect Nonhuman Primates from Lethal Disease
Lethal experimental infection of rhesus monkeys with Ebola-Zaire (Mayinga) virus by the oral and conjunctival route of exposure PubMed, February 1996, Jaax et al.
Lethal experimental infections of rhesus monkeys by aerosolized Ebola and marburg virus PubMed, August 1995
Marburg and Ebola viruses as aerosol threats PubMed, 2004, USAMRIID
Other viral bioweapons: Ebola and Marburg hemorrhag fever PubMed, 2004
Transmission of Ebola virus (Zaire strain) to uninfected control monkeys in a biocontainment laboratory PubMed, December 1993
What is the probability of a dangerous strain of Ebola mutating and becoming airborne? Brett Russel, retrieved 2006-07-10.

Template:Viral diseases

Template:Jb1 Template:WH Template:WS

@@ Line 55: / Line 55: @@
 [[Ebola medical therapy|Medical therapy]] | [[Ebola primary prevention|Primary prevention]]  | [[Ebola secondary prevention|Secondary prevention]] | [[Ebola cost-effectiveness of therapy|Financial costs]] | [[Ebola future or investigational therapies|Future therapies]]
-==Viral reservoirs==
-Despite numerous studies, the wildlife reservoir of ''Ebolavirus'' has not been identified. Between 1976 and 1998, from 30,000 mammals, birds, reptiles, amphibians, and arthropods sampled from outbreak regions, no ''Ebolavirus'' was detected <ref name="Pourrut2005">{{cite journal |last=Pourrut |first=Xavier |authorlink= |coauthors=''et al.'' |year=2005 |month= |title=The natural history of Ebola virus in Africa |journal=Microbes and Infection |volume=7 |issue=7-8 |pages=1005-1014 |doi=10.1016/j.micinf.2005.04.006 |url= |accessdate= |quote= }}</ref> apart from some genetic material found in six rodents (''Mus setulosus'' and  ''Praomys'' species) and a [[shrew]] (''Sylvisorex ollula'') collected from the [[Central African Republic]] in 1998.<ref name="Morvan1999">{{cite journal |last=Morvan |first=Jaques |authorlink= |coauthors=''et al.'' |year=1999 |month= |title=Identification of Ebola virus sequences present as RNA or DNA in organs of terrestrial small mammals of the Central African Republic |journal=Microbes and Infection |volume=1 |issue=14 |pages=1193-1201 |doi=10.1016/S1286-4579(99)00242-7 |url= |accessdate= |quote= }}</ref> ''Ebolavirus'' was detected in the carcasses of [[gorilla]]s, chimpanzees and [[duiker]]s during outbreaks in 2001 and 2003 (the carcasses were the source of the initial human infections) but the high mortality from infection in these species precludes them from acting as reservoirs.<ref name="Pourrut2005" />
-[[Plant]]s, [[arthropods]], and birds have also been considered as reservoirs, however bats are considered the most likely candidate<ref>{{cite news |first= |last= |authorlink= |coauthors= |title=Fruit bats may carry Ebola virus |url=http://news.bbc.co.uk/2/hi/health/4484494.stm |work=BBC News |publisher= |date=2005-12-11 |accessdate=2008-02-25 }}</ref>. Bats were known to reside in the cotton factory in which the index cases for the 1976 and 1979 outbreaks were employed and have also been implicated in Marburg infections in 1975 and 1980.<ref name="Pourrut2005" /> Of 24 plant species and 19 vertebrate species experimentally inoculated with  ''Ebolavirus'', only bats became infected.<ref>{{cite journal |last=Swanepoel |first=R |authorlink= |coauthors=''et al.'' |year=1996 |month= |title=Experimental inoculation of plants and animals with Ebola virus |journal=Emerging Infectious Diseases |volume=2 |issue= |pages=321-325 |doi= |url=http://www.cdc.gov/ncidod/eid/vol2no4/swanepo2.htm |accessdate= |quote= }}</ref> The absence of clinical signs in these bats is characteristic of a reservoir species. In 2002-03, a survey of 1,030 animals from [[Gabon]] and the [[Republic of the Congo]] including 679 bats found ''Ebolavirus'' RNA in 13 [[fruit bats]] (''Hyspignathus monstrosus, Epomops franquetti and Myonycteris torquata'').<ref>{{cite journal |last=Leroy |first=Eric |authorlink= |coauthors=''et al.'' |year=2005 |month= |title=Fruit bats as reservoirs of Ebola virus |journal=Nature |volume=438 |issue= |pages=575-576 |doi=10.1038/438575a |url= |accessdate= |quote= }}</ref> Bats are also known to be the reservoirs for a number of related viruses including [[Nipah virus]], [[Hendra virus]] and [[lyssavirus]]es.
 ==See also==

Ebola: Difference between revisions

Revision as of 16:00, 5 April 2012

Contents

Overview

Classification

Historical Perspective

Pathophysiology

Epidemiology & Demographics

Risk Factors

Causes

Differentiating Ebola

Natural history, Complications, and Prognosis

Diagnosis

Treatment

See also

References

External links

Navigation menu

Ebola
ICD-10	A98.4
ICD-9	065.8
DiseasesDB	18043
MedlinePlus	001339
MeSH	C02.782.417.415

Ebola: Difference between revisions

Revision as of 16:00, 5 April 2012

Diagnosis

Treatment

See also

References

External links

Navigation menu

Search