|
|
| Line 56: |
Line 56: |
|
| |
|
| ==Diagnostic Findings== | | ==Diagnostic Findings== |
|
| |
| ===Microscopic Images===
| |
|
| |
| [http://www.peir.net Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology]
| |
|
| |
|
| |
| <gallery perRow="3">
| |
| Image:Systemic lupus erythematosus 003.jpg|Lupus erythematosus hepatitis: Micro high mag H&E, periportal sinus thrombosis with liver cell necrosis and noninflammatory infiltrate (possibly viral). A 19yo female with lupus erythematosus
| |
| Image:Systemic lupus erythematosus 005.jpg|Spleen: Lupus erythematosus Periarterial Fibrosis: Micro high may H&E. An excellent example of periarterial fibrosis
| |
| Image:Systemic lupus erythematosus 006.jpg|Spleen: Lupus erythematosus, periarterial fibrosis: Micro high may H&E. An excellent example of periarterial fibrosis
| |
| Image:Systemic lupus erythematosus 007.jpg|Spleen: Lupus erythematosus. Basophilic bodies and periarterial fibrosis: Micro high mag, H&E. Two basophilic bodies and periarterial fibrosis. An excellent example of this rarely seen lupus lesion.
| |
| Image:Systemic lupus erythematosus 008.jpg|Lupus Erythematosus, Libman Sacks Endocarditis: Micro low mag trichrome stain thickened valve leaflet with small mural fibrin deposit. A 19yo female with cerebral lupus in form of TIAs due to this lesion.
| |
| Image:Systemic lupus erythematosus 009.jpg|Lupus Erythematosus, Libman Sacks Endocarditis: Micro low mag, elastic van Gieson stain, mitral valve thickened, leaflet with small mural fibrin deposit that caused TIAs in 19yo female
| |
| Image:Systemic lupus erythematosus 010.jpg|Adrenal: Autoimmune Adrenalitis: Micro high mag H&E focal area of lymphocytic infiltration in zona reticularis in a 19yo female with lupus erythematosus
| |
| Image:Systemic lupus erythematosus 039.jpg|Kidney: Lupus Erythematosus: Micro high mag H&E. A nice example of a lesion of chronic glomerulonephritis with lobular scarring. A fibrous type crescent.
| |
| Image:Systemic lupus erythematosus 011.jpg|Kidney: Lupus Erythematosus: Micro high mag H&E two glomeruli showing mesangial thickening and focal wire loop type lesions 19yo female with renal failure and embolic brain disease from Libman Sacks lesion on mitral valve
| |
| Image:Systemic lupus erythematosus 012.jpg|Lupus Erythematosus Myocardial Necrosis Due To Libman Sacks: Micro low mag H&E focal myocardial necrosis due to embolism from Libman Sacks lesion on mitral valve 19yo female with TIAs due to mitral lesion
| |
| Image:Systemic lupus erythematosus 013.jpg|Lupus Erythematosus Focal Myocardial Scar Due To Libman Sacks Embolism: Micro low mag H&E focal scar in myocardium due to embolism
| |
| Image:Systemic lupus erythematosus 014.jpg|Lupus Erythematosus Myocardial Scar Due To Libman Sacks Embolism: Micro low mag H&E scar with portion of embolus in small artery
| |
| Image:Systemic lupus erythematosus 015.jpg|Lupus Erythematosus Myocardial Necrosis Due To Libman Sacks: Micro low mag H&E well shown focal myocardial necrosis due to embolism from mitral Libman Sacks lesion
| |
| Image:Systemic lupus erythematosus 016.jpg|Lupus Erythematosus Embolus From Libman Sacks Lesion: Micro med mag H&E well shown embolus in small artery
| |
| Image:Systemic lupus erythematosus 017.jpg|Lupus Erythematosus Hepatitis: Micro low mag trichrome stain periportal liver cell necrosis and sinus thrombosis with no inflammatory reaction cause unknown 19yo female with lupus erythematosus
| |
| Image:Systemic lupus erythematosus 018.jpg|Lung: Diffuse Alveolar Damage: Gross natural color section of both lungs with frank meaty appearance case of lupus erythematosus in 19yo female
| |
| Image:Systemic lupus erythematosus 020.jpg|Lung: Necrotizing Bronchiolitis: Micro low mag H&E well shown lesion in lung that grossly looked like diffuse alveolar damage which indeed has lesions of this type additionally 19yo female with lupus erythematosus
| |
| Image:Systemic lupus erythematosus 023.jpg|Lupus Erythematosus Libman Sacks Endocarditis: Micro low mag H&E mitral valve lesion with easily seen mural thrombi and focal necrobiosis of collagen in thickened valve leaflet 19yo female
| |
| Image:Systemic lupus erythematosus 024.jpg|Lung: Necrotizing Bronchiolitis: Micro low mag H&E well shown necrotizing bronchiolitis and surrounding lesions of diffuse alveolar damage 19yo female with lupus erythematosus
| |
| Image:Systemic lupus erythematosus 025.jpg|Myocarditis: Micro high mag H&E focal myofiber necrosis typical for this diagnosis but this is case of lupus erythematosus with Libman Sacks lesion and brain emboli and heart emboli did she also have viral myocarditis? This lesion is typical for the diagnosis
| |
| Image:Systemic lupus erythematosus 026.jpg|Kidney: Lupus Erythematosus: Micro high mag PAS stain thickened mesangium and capillary basement membranes 19yo female with renal failure and proved lupus
| |
| Image:Systemic lupus erythematosus 033.jpg|Artery: Arteritis in Lupus Erythematosus: Micro med mag H&E. A good example of vasculitis
| |
| Image:Systemic lupus erythematosus 034.jpg|Kidney: Lupus Erythematosus: Micro high mag PASH typical glomerulonephritis lesion with crescent
| |
| Image:Systemic lupus erythematosus 035.jpg|Kidney: Lupus Erythematosus: Micro med mag PASH glomerulonephritis
| |
| Image:Systemic lupus erythematosus 036.jpg|Kidney: Lupus Erythematosus: Micro med mag H&E typical glomerulonephritis lesion
| |
| Image:Systemic lupus erythematosus 037.jpg|Kidney: Lupus Erythematosus: Micro med mag H&E two glomeruli showing lobular glomerulonephritis lesion
| |
| Image:Systemic lupus erythematosus 038.jpg|Kidney: Lupus Erythematosus: Micro med mag PASH typical chronic glomerulonephritis lesion with crescent
| |
| Image:Systemic lupus erythematosus 048.jpg|Vessel: lupus, systemic erythematosus; Thrombus in capillary
| |
| Image:Systemic lupus erythematosus 049.jpg|Vessel: lupus, systemic erythematosus; Thrombus in capillary
| |
| Image:Systemic lupus erythematosus 050.jpg|Vessel: lupus, systemic erythematosus; Thrombus in arteriole and vein
| |
| Image:Systemic lupus erythematosus 051.jpg|Vessel: lupus, systemic erythematosus; Thrombus in pial vessel
| |
| Image:Systemic lupus erythematosus 022.jpg|Lupus Erythematosus Libman Sacks Endocarditis: Micro high mag H&E atrial surface of mitral valve with small fibrin thrombus representing Libman Sacks lesion 10yo female
| |
| </gallery>
| |
|
| |
|
| ==Videos== | | ==Videos== |
