Systemic lupus erythematosus causes: Difference between revisions
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==Causes== | ==Causes== | ||
Despite the dramatic rise in | Despite the dramatic rise in '''lupus''' research in recent years, the exact cause of the disease remains unknown. Indeed, consensus is still lacking on whether lupus is a single condition or a group of related diseases. [[SLE]] is a chronic [[inflammation|inflammatory]] disease believed to be a [[Hypersensitivity#Type III - immune complex|type III hypersensitivity]] response with potential [[Hypersensitivity#Type 2 - antibody-dependent|type II]] involvement,<ref>[http://pathmicro.med.sc.edu/ghaffar/hyper00.htm University of South Carolina lecture on immunology]</ref> characterized by the body's production of antibodies against the nuclear components of its own cells. There are three mechanisms by which lupus is thought to develop: | ||
* Genetic predisposition | |||
* Environmental triggers | |||
* Drug reaction ([[drug-induced lupus]]) - here are about 400 medications currently in use that can cause this condition, though the most common drugs are | |||
** [[Procainamide]] | |||
** [[Hydralazine]] | |||
** [[Quinidine]] | |||
==References== | ==References== | ||
Revision as of 13:13, 3 August 2012
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Systemic lupus erythematosus Microchapters |
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Differentiating Systemic lupus erythematosus from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Systemic lupus erythematosus causes On the Web |
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American Roentgen Ray Society Images of Systemic lupus erythematosus causes |
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Directions to Hospitals Treating Systemic lupus erythematosus |
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Risk calculators and risk factors for Systemic lupus erythematosus causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]
Overview
Causes
Despite the dramatic rise in lupus research in recent years, the exact cause of the disease remains unknown. Indeed, consensus is still lacking on whether lupus is a single condition or a group of related diseases. SLE is a chronic inflammatory disease believed to be a type III hypersensitivity response with potential type II involvement,[1] characterized by the body's production of antibodies against the nuclear components of its own cells. There are three mechanisms by which lupus is thought to develop:
- Genetic predisposition
- Environmental triggers
- Drug reaction (drug-induced lupus) - here are about 400 medications currently in use that can cause this condition, though the most common drugs are
References