Chlortetracycline: Difference between revisions
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'''Chlortetracycline''' (trade name '''Aureomycin®''', [[Lederle]]) is a [[Tetracycline antibiotics|tetracycline]] [[antibiotic]], and was the first tetracycline to be discovered. It was discovered in [[1945]] by Dr [[Benjamin Duggar]] in a soil sample from [[Sanborn Field]] at the [[University of Missouri]], yielding an [[actinomycete]], ''Streptomyces aureofaciens'' (hence the name Aureomycin). In [[veterinary medicine]], it is commonly used to treat [[conjunctivitis]] in [[Felines|cats]].<ref name="Merck">{{cite book | title=Merck Veterinary Manual | url=http://merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/30200.htm }}</ref> | '''Chlortetracycline''' (trade name '''Aureomycin®''', [[Lederle]]) is a [[Tetracycline antibiotics|tetracycline]] [[antibiotic]], and was the first tetracycline to be discovered. It was discovered in [[1945]] by Dr [[Benjamin Duggar]] in a soil sample from [[Sanborn Field]] at the [[University of Missouri]], yielding an [[actinomycete]], ''Streptomyces aureofaciens'' (hence the name Aureomycin). In [[veterinary medicine]], it is commonly used to treat [[conjunctivitis]] in [[Felines|cats]].<ref name="Merck">{{cite book | title=Merck Veterinary Manual | url=http://merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/30200.htm }}</ref> | ||
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Revision as of 23:48, 8 August 2012
| File:Chlortetracycline.svg | |
| Clinical data | |
|---|---|
| Routes of administration | Oral, IV, topical |
| ATC code | |
| Pharmacokinetic data | |
| Bioavailability | 30% |
| Protein binding | 50 to 55% |
| Metabolism | Hepatic (75%) |
| Elimination half-life | 5.6 to 9 hours |
| Excretion | Renal and biliary |
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| CAS Number | |
| PubChem CID | |
| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C22H23ClN2O8 |
| Molar mass | 478.879 g/mol |
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Chlortetracycline (trade name Aureomycin®, Lederle) is a tetracycline antibiotic, and was the first tetracycline to be discovered. It was discovered in 1945 by Dr Benjamin Duggar in a soil sample from Sanborn Field at the University of Missouri, yielding an actinomycete, Streptomyces aureofaciens (hence the name Aureomycin). In veterinary medicine, it is commonly used to treat conjunctivitis in cats.[1]
References
de:Chlortetracyclin sv:Aureomycin th:คลอเตตร้าซัยคลิน uk:Хлортетрациклін
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- Tetracycline antibiotics