Acute liver failure classification: Difference between revisions
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Created page with "__NOTOC__ {{Acute liver failure}} {{CMG}} ==Overview== ==References== {{reflist|2}} {{WH}} {{WS}}" |
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==Overview== | ==Overview== | ||
==Classification== | |||
'''1)''' The 1993 classification defines <ref>O'Grady JG, Schalm SW, Williams R. Acute liver failure: redefining the syndromes. ''[[The Lancet|Lancet]] 1993;342:273-5. PMID 8101303.</ref> It reflects the fact that the pace of disease evolution strongly influence prognosis. Underlying [[aetiology]] is the other significant determinant of outcome.<ref name="ogredy1">{{cite journal |author=O'Grady JG |title=Acute liver failure |journal=Postgraduate medical journal |volume=81 |issue=953 |pages=148-54 |year=2005 |pmid=15749789 |doi=10.1136/pgmj.2004.026005}}</ref> | |||
* ''Hyperacute'' as within 1 week, | |||
* ''Acute'' as 8-28 days and | |||
* ''Subacute'' as 4-12 weeks | |||
'''2)''' Acute liver failure may be fulminant or subfulminant. Both the forms have poor prognosis | |||
* ''Fulminant hepatic failure'' - Development of [[hepatic encephalopathy]] within 2 months after the onset of acute liver disease. | |||
* ''Subfulminant hepatic failure'' - Development of hepatic encephalopathy within 2 months to 6 months after the onset of acute liver disease | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
Revision as of 20:10, 28 August 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Classification
1) The 1993 classification defines [1] It reflects the fact that the pace of disease evolution strongly influence prognosis. Underlying aetiology is the other significant determinant of outcome.[2]
- Hyperacute as within 1 week,
- Acute as 8-28 days and
- Subacute as 4-12 weeks
2) Acute liver failure may be fulminant or subfulminant. Both the forms have poor prognosis
- Fulminant hepatic failure - Development of hepatic encephalopathy within 2 months after the onset of acute liver disease.
- Subfulminant hepatic failure - Development of hepatic encephalopathy within 2 months to 6 months after the onset of acute liver disease