Neuroblastoma natural history: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
__NOTOC__ | |||
{{Neuroblastoma}} | {{Neuroblastoma}} | ||
{{CMG}} | {{CMG}} | ||
== Post-treatment prognosis == | ==Overview== | ||
==Natural History== | |||
==Complications== | |||
*Spread (metastasis) of the tumor | |||
*Damage and loss of function of involved organ(s) | |||
**Kidney failure | |||
**Liver failure | |||
**Loss of blood cells produced by the bone marrow | |||
**Decreased resistance to infection | |||
**Other organ system failures | |||
==Prognosis== | |||
The prognosis of neuroblastoma is poor and it depends on the following: | |||
:*Whether or not the tumor can be removed by surgery. | |||
:*The stage of the cancer: the size of the tumor, whether the cancer has spread | |||
:*The child’s general health | |||
=== Post-treatment prognosis === | |||
After it is declared that the disease is gone, it often comes back. Further treatment is then required. This can be problematic because some treatments, such as [[chemotherapy]], have cumulative effects and side-effects therefore can increase significantly if used again. | After it is declared that the disease is gone, it often comes back. Further treatment is then required. This can be problematic because some treatments, such as [[chemotherapy]], have cumulative effects and side-effects therefore can increase significantly if used again. | ||
Revision as of 18:20, 10 September 2012
|
Neuroblastoma Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Neuroblastoma natural history On the Web |
|
American Roentgen Ray Society Images of Neuroblastoma natural history |
|
Risk calculators and risk factors for Neuroblastoma natural history |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Natural History
Complications
- Spread (metastasis) of the tumor
- Damage and loss of function of involved organ(s)
- Kidney failure
- Liver failure
- Loss of blood cells produced by the bone marrow
- Decreased resistance to infection
- Other organ system failures
Prognosis
The prognosis of neuroblastoma is poor and it depends on the following:
- Whether or not the tumor can be removed by surgery.
- The stage of the cancer: the size of the tumor, whether the cancer has spread
- The child’s general health
Post-treatment prognosis
After it is declared that the disease is gone, it often comes back. Further treatment is then required. This can be problematic because some treatments, such as chemotherapy, have cumulative effects and side-effects therefore can increase significantly if used again.
Intensive chemotherapy and radiation therapy have known long-term negative consequences. An estimated two of three survivors of childhood cancer will ultimately develop at least one chronic and sometimes life-threatening health problem within 20 to 30 years after the cancer diagnosis.[1][2]
References
- ↑ "Childhood Cancer Survivors Face Increased Sarcoma Risk", HealthDay News, February 21, 2007
- ↑ Oeffinger et al.,"Chronic Health Conditions in Adult Survivors of Childhood Cancer", New England Journal of Medicine, October 12, 2006