Dysplastic nevus pathophysiology: Difference between revisions
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==Pathophysiology== | ==Pathophysiology== | ||
===Associated conditions=== | ===Associated conditions=== | ||
;Atypical Mole Syndrome | |||
Atypical Mole Syndrome is a hereditary condition which causes the person to have a large quantity of moles (often 100 or more) with some dysplastic nevi. This often leads to a higher [[risk]] of [[melanoma]], a serious [[skin cancer]].<ref>Burkhart, C.G MPH, MD. Dysplastic nevus declassified; even the NIH recommends elimination of confusing terminology. SKINmed: Dermatology for the Clinician 2(1):12-13, 2003.</ref> | |||
A slight majority of melanomas do ''not'' form in an existing mole, but rather create a new [[growth]] on the skin. Nevertheless, those with more dysplastic nevi are at a higher risk of this type of melanoma occurrence.<ref>D.J. Pope, T. Sorahan, J.R. Marsden, P.M. Ball, R.P. Grimley and I.M. Peck. Benign pigmented nevi in children. Arch of Dermatology 2006;142:1599-1604</ref><ref>D.E. Goldgar, L.A. Cannon-Albright, L.J. Meyer, M.W. Pipekorn, J.J. Zone, M.H. Skolnick. Inheritance of Nevus Number and Size in Melanoma and Dysplastic Nevus Syndrome Kindreds. Journal of the National Cancer Institute 1991 83(23):1726-1733</ref> Such persons need to be checked regularly for any changes in their moles and to note any new ones. | |||
==References== | ==References== | ||
Revision as of 15:05, 18 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pathophysiology
Associated conditions
- Atypical Mole Syndrome
Atypical Mole Syndrome is a hereditary condition which causes the person to have a large quantity of moles (often 100 or more) with some dysplastic nevi. This often leads to a higher risk of melanoma, a serious skin cancer.[1] A slight majority of melanomas do not form in an existing mole, but rather create a new growth on the skin. Nevertheless, those with more dysplastic nevi are at a higher risk of this type of melanoma occurrence.[2][3] Such persons need to be checked regularly for any changes in their moles and to note any new ones.
References
- ↑ Burkhart, C.G MPH, MD. Dysplastic nevus declassified; even the NIH recommends elimination of confusing terminology. SKINmed: Dermatology for the Clinician 2(1):12-13, 2003.
- ↑ D.J. Pope, T. Sorahan, J.R. Marsden, P.M. Ball, R.P. Grimley and I.M. Peck. Benign pigmented nevi in children. Arch of Dermatology 2006;142:1599-1604
- ↑ D.E. Goldgar, L.A. Cannon-Albright, L.J. Meyer, M.W. Pipekorn, J.J. Zone, M.H. Skolnick. Inheritance of Nevus Number and Size in Melanoma and Dysplastic Nevus Syndrome Kindreds. Journal of the National Cancer Institute 1991 83(23):1726-1733