Growth hormone deficiency causes: Difference between revisions
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* Damage to the pituitary from [[radiation therapy]] to the head for [[leukemia]] or [[brain tumor]]s, | * Damage to the pituitary from [[radiation therapy]] to the head for [[leukemia]] or [[brain tumor]]s, | ||
* Surgery in the area of the pituitary, | * Surgery in the area of the pituitary, | ||
* [[autoimmunity|Autoimmune]] [[inflammation]] (hypophysitis), | * [[autoimmunity|Autoimmune]] [[inflammation]] ([[hypophysitis]]), | ||
* Severe [[head trauma]], | * Severe [[head trauma]], | ||
* [[Ischemia|Ischemic]] or hemorrhagic infarction from low blood pressure ([[Sheehan syndrome]]) or hemorrhage [[pituitary apoplexy]]. | * [[Ischemia|Ischemic]] or hemorrhagic infarction from low blood pressure ([[Sheehan syndrome]]) or hemorrhage [[pituitary apoplexy]]. |
Revision as of 15:06, 19 September 2012
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Differentiating Growth hormone deficiency from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Causes
There are many causes of GH deficiency. Some examples include:
- Mutations of specific genes (e.g., GHRHR, GH1)
- Congenital malformations involving the pituitary (e.g., septo-optic dysplasia, posterior pituitary ectopia)
- Damage to the pituitary from incracranial disease (e.g., hydrocephalus),
- Intracranial tumors in or near the sella turcica, especially craniopharyngioma,
- Damage to the pituitary from radiation therapy to the head for leukemia or brain tumors,
- Surgery in the area of the pituitary,
- Autoimmune inflammation (hypophysitis),
- Severe head trauma,
- Ischemic or hemorrhagic infarction from low blood pressure (Sheehan syndrome) or hemorrhage pituitary apoplexy.