Membranous glomerulonephritis overview: Difference between revisions
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==Overview== | ==Overview== | ||
'''Membranous glomerulonephritis''' ('''MGN'''), also known as '''membranous nephropathy''', is a slowly progressive disease of the [[kidney]] affecting mostly patients between ages of 30 and 50 years. 85% of MGN cases are classified as ''primary membranous glomerulonephritis'' -- that is to say, the cause of the disease is idiopathic (unknown). This can also be referred to as ''idiopathic membranous nephropathy''. The remainder is secondary due to : | |||
* '''autoimmune conditions''' (e.g., systemic lupus erythematosus) | |||
* '''infections''' (e.g., syphilis, malaria, hepatitis B) | |||
* '''drugs''' (e.g., captopril, NSAIDs) | |||
* '''inorganic salts''' | |||
* '''malignant tumors''' (in particular, carcinoma of the lung and colon, and melanoma) | |||
The word ''membranous'' refers to the [[Glomerular_basement_membrane|glomerular basement membrane]] of the kidney; ''glomerulonephritis'' means "a kidney disease affecting the capillaries of the [[Glomerulus|glomeruli]]"; ''[[nephropathy]]'' is a generic term that just refers to any disease of the kidney. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} |
Revision as of 20:03, 27 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Membranous glomerulonephritis (MGN), also known as membranous nephropathy, is a slowly progressive disease of the kidney affecting mostly patients between ages of 30 and 50 years. 85% of MGN cases are classified as primary membranous glomerulonephritis -- that is to say, the cause of the disease is idiopathic (unknown). This can also be referred to as idiopathic membranous nephropathy. The remainder is secondary due to :
- autoimmune conditions (e.g., systemic lupus erythematosus)
- infections (e.g., syphilis, malaria, hepatitis B)
- drugs (e.g., captopril, NSAIDs)
- inorganic salts
- malignant tumors (in particular, carcinoma of the lung and colon, and melanoma)
The word membranous refers to the glomerular basement membrane of the kidney; glomerulonephritis means "a kidney disease affecting the capillaries of the glomeruli"; nephropathy is a generic term that just refers to any disease of the kidney.