Hepatorenal syndrome epidemiology and demographics: Difference between revisions
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==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
It is estimated that 39% of patients with [[cirrhosis]] and [[ascites]] will develop hepatorenal syndrome within five years of the onset of their disease. | It is estimated that 39% of patients with [[cirrhosis]] and [[ascites]] will develop hepatorenal syndrome within five years of the onset of their disease. The prognosis of these patients is grim with untreated patients having an extremely short survival, and with the severity of liver disease (as evidenced by the [[Model for End-Stage Liver Disease|MELD]] score) now believed to determine outcome.<ref>Alessandria C, Ozdogan O, Guevara M, Restuccia T, Jimenez W, Arroyo V, Rodes J, Gines P. MELD score and clinical type predict prognosis in hepatorenal syndrome: Relevance to liver transplantation. ''Hepatology'' 2005 Jun;41(6):1282-9. PMID 15834937</ref> Some patients without cirrhosis develop hepatorenal syndrome, with an incidence of about 20% seen in one study of ill patients with [[alcoholic hepatitis]].<ref>Akriviadis E, Botla R, Briggs W, Han S, Reynolds T, Shakil O. Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial. ''Gastroenterology'' 2000 Dec;119(6):1637-48. PMID 11113085.</ref> | ||
==References== | ==References== | ||
Revision as of 13:26, 28 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Epidemiology and Demographics
It is estimated that 39% of patients with cirrhosis and ascites will develop hepatorenal syndrome within five years of the onset of their disease. The prognosis of these patients is grim with untreated patients having an extremely short survival, and with the severity of liver disease (as evidenced by the MELD score) now believed to determine outcome.[1] Some patients without cirrhosis develop hepatorenal syndrome, with an incidence of about 20% seen in one study of ill patients with alcoholic hepatitis.[2]
References
- ↑ Alessandria C, Ozdogan O, Guevara M, Restuccia T, Jimenez W, Arroyo V, Rodes J, Gines P. MELD score and clinical type predict prognosis in hepatorenal syndrome: Relevance to liver transplantation. Hepatology 2005 Jun;41(6):1282-9. PMID 15834937
- ↑ Akriviadis E, Botla R, Briggs W, Han S, Reynolds T, Shakil O. Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial. Gastroenterology 2000 Dec;119(6):1637-48. PMID 11113085.