Lupus nephritis pathophysiology: Difference between revisions
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==Overview== | ==Overview== | ||
==Pathophysiology== | |||
Systemic lupus erythematosus (SLE, or lupus) is an [[autoimmune]] disease. This means there is a problem with the body's immune system. | |||
Normally, the immune system helps protect the body from harmful substances. But in patients with an autoimmune disease, the immune system cannot tell the difference between harmful substances and healthy ones. As a result, the immune system attacks otherwise healthy cells and tissue. | |||
===Gross Pathology=== | |||
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| [[Image:Systemic lupus erythematosus 001.jpg|thumb|Gross, enlarged very pale kidneys with flea bite or ectasia. A good example of kidneys from a patient with nephrotic syndrome (subacute glomerulonephritis)]] | |||
| [[Image:Systemic lupus erythematosus 002.jpg|thumb|Gross cut surface pale kidneys typical of nephrotic syndrome (subacute glomerulonephritis)]] | |||
| [[Image:Systemic lupus erythematosus 046.jpg|thumb|Gross natural color nice external and cut surface view of uniformly scarred and moderately shrunken kidneys]] | |||
| [[Image:Systemic lupus erythematosus 019.jpg|thumb|Micro high mag H&E increased mesangial tissue and wire loops 10yo female with renal failure and TIAs due to Libman Sacks endocarditis]] | |||
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===Microscopic Pathology=== | |||
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|[[Image:Systemic lupus erythematosus 039.jpg|thumb|Kidney: Lupus Erythematosus: Micro high mag H&E. A nice example of a lesion of chronic glomerulonephritis with lobular scarring. A fibrous type crescent.]] | |||
|[[Image:Systemic lupus erythematosus 011.jpg|thumb|Kidney: Lupus Erythematosus: Micro high mag H&E two glomeruli showing mesangial thickening and focal wire loop type lesions 19yo female with renal failure and embolic brain disease from Libman Sacks lesion on mitral valve ]] | |||
|[[Image:Systemic lupus erythematosus 035.jpg|thumb|Kidney: Lupus Erythematosus: Micro med mag PASH glomerulonephritis]] | |||
|[[Image:Systemic lupus erythematosus 036.jpg|thumb|Kidney: Lupus Erythematosus: Micro med mag H&E typical glomerulonephritis lesion]] | |||
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====Videos==== | |||
{{#ev:youtube|Tw07BFaDEo0}} | |||
==References== | ==References== | ||
Revision as of 13:45, 28 September 2012
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Lupus nephritis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Lupus nephritis pathophysiology On the Web |
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American Roentgen Ray Society Images of Lupus nephritis pathophysiology |
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Risk calculators and risk factors for Lupus nephritis pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2], Raviteja Guddeti, M.B.B.S. [3]
Overview
Pathophysiology
Systemic lupus erythematosus (SLE, or lupus) is an autoimmune disease. This means there is a problem with the body's immune system.
Normally, the immune system helps protect the body from harmful substances. But in patients with an autoimmune disease, the immune system cannot tell the difference between harmful substances and healthy ones. As a result, the immune system attacks otherwise healthy cells and tissue.
Gross Pathology
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Microscopic Pathology
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Videos
{{#ev:youtube|Tw07BFaDEo0}}