Patent ductus arteriosus causes

Patent Ductus Arteriosus Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Priyamvada Singh, M.B.B.S. [2], Cafer Zorkun, M.D., Ph.D. [3], Assistant Editor-In-Chief: Kristin Feeney, B.S. [4]

Overview

Causes of Patent ductus arteriosus is not known. However, increased incidence have been associated with mother's rubella and genetic causes

Causes

• Genetic factors - It has been found to occur with increased frequencies in some families, indicating some association with autosomal dominant inheritence . The exact gene location for patent ductus arteriosus has not yet been determined.
• Congenital rubella (associated with PDA and pulmonary artery stenosis)
• Fetal alcohol syndrome
• Maternal drug use
  • amphetamine
  • phenytoin