Acute liver failure classification: Difference between revisions
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Acute liver failure can be classified into fulminant or subfulminant. Both the forms have poor prognosis. It is based upon the duration between onset of hepatic illness to development of encephalopathy. | Acute liver failure can be classified into fulminant or subfulminant. Both the forms have poor prognosis. It is based upon the duration between onset of hepatic illness to development of encephalopathy. | ||
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! Classification !! Time for Hepatic Encephalopathy | |||
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| Fulminant || within 2 months | |||
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|Subfulminant || within 2 months to 6 months | |||
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* ''Fulminant hepatic failure'' - Development of | * ''Fulminant hepatic failure'' - Development of after the onset of acute liver disease. | ||
* ''Subfulminant hepatic failure'' - Development of hepatic encephalopathy within 2 months to 6 months after the onset of acute liver disease | * ''Subfulminant hepatic failure'' - Development of hepatic encephalopathy within 2 months to 6 months after the onset of acute liver disease | ||
Revision as of 01:36, 27 October 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
Overview
Acute liver failure is classified into hyperacute , acute and subacute depending upon the time lapsed between appearance of jaundice to encephalopathy. It is also classified into fulminant an subfulminant basing upon the time lapsed from start if illness to onset of encephalopathy.
Classification
The 1993 classification defines [1] It reflects the fact that the pace of disease evolution strongly influence prognosis. Underlying aetiology is the other significant determinant of outcome.[2] It is based upon the duration between onset of jaundice to onset of encephalopathy.
| Time | Classification |
|---|---|
| 1 week | Hyperacute |
| 1 week - 1 month | Acute |
| 1 week - 3 months | Subacute |
Acute liver failure can be classified into fulminant or subfulminant. Both the forms have poor prognosis. It is based upon the duration between onset of hepatic illness to development of encephalopathy.
| Classification | Time for Hepatic Encephalopathy |
|---|---|
| Fulminant | within 2 months |
| Subfulminant | within 2 months to 6 months |
- Fulminant hepatic failure - Development of after the onset of acute liver disease.
- Subfulminant hepatic failure - Development of hepatic encephalopathy within 2 months to 6 months after the onset of acute liver disease