Raynaud's phenomenon medical therapy: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 2: | Line 2: | ||
{{Raynaud's phenomenon}} | {{Raynaud's phenomenon}} | ||
'''Editors-In-Chief:''' Asghar Fakhri, M.D., Duane S. Pinto, M.D. and [[User:C Michael Gibson|C. Michael Gibson, M.S., M.D.]] | '''Editors-In-Chief:''' Asghar Fakhri, M.D., Duane S. Pinto, M.D. and [[User:C Michael Gibson|C. Michael Gibson, M.S., M.D.]] | ||
==Overview== | ==Overview== | ||
Treatment options are dependent on the type of Raynaud's present. Raynaud's syndrome is treated primarily by addressing the underlying cause, but includes all options for Raynaud's disease as well. | Treatment options are dependent on the type of Raynaud's present. Raynaud's syndrome is treated primarily by addressing the underlying cause, but includes all options for Raynaud's disease as well. | ||
| Line 15: | Line 16: | ||
== References == | == References == | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Rheumatology]] | |||
[[Category:Syndromes]] | |||
[[Category:Autoimmune diseases]] | |||
{{WikiDoc Help Menu}} | {{WikiDoc Help Menu}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
Latest revision as of 19:14, 8 November 2012
|
Raynaud's phenomenon Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Raynaud's phenomenon medical therapy On the Web |
|
American Roentgen Ray Society Images of Raynaud's phenomenon medical therapy |
|
Risk calculators and risk factors for Raynaud's phenomenon medical therapy |
Editors-In-Chief: Asghar Fakhri, M.D., Duane S. Pinto, M.D. and C. Michael Gibson, M.S., M.D.
Overview
Treatment options are dependent on the type of Raynaud's present. Raynaud's syndrome is treated primarily by addressing the underlying cause, but includes all options for Raynaud's disease as well.
Medical Therapy
- Drug treatment is normally with a calcium channel blocker, frequently nifedipine to prevent arterioconstriction. It has the usual side effects of headache, flushing, and ankle edema, and patients often stop treatment, preferring the symptoms of Raynaud's to the symptoms of the drug.
- The extract of the Ginkgo biloba leaves (Egb 761, 80mg) reduces symptoms in two weeks.
- There is some evidence that Angiotensin II receptor antagonists (often Losartan) reduce frequency and severity of attacks.
- In intractable cases, sympathectomy and infusions of prostaglandins, e.g. prostacyclin, may be tried, with amputation in exceptionally severe cases.
- Alpha-1 adrenergic blockers such as prazosin can be used to control Raynaud's vasospasms under supervision of a health care provider.
- In a study published in the November 8, 2005 issue of Circulation, sildenafil (Viagra) improved both microcirculation and symptoms in patients with secondary Raynaud's phenomenon resistant to vasodilatory therapy. The authors, led by Dr Roland Fries (Gotthard-Schettler-Klinik, Bad Schönborn, Germany), report: "In the present study, capillary blood flow was severely impaired and sometimes hardly detectable in patients with Raynaud's phenomenon. Sildenafil led to a more than 400% increase of flow velocity."
- Two separate gels combined on the fingertip (somewhat like two-part epoxy, they cannot be combined before use because they will react) increased blood flow in the fingertips by about three times. One gel contained 5% sodium nitrite and the other contained 5% ascorbic acid. The milliliter of combined gel covered an area of ~3 cm². The gel was wiped off after a few seconds. Tucker, A.T. et al., The Lancet, Vol. 354, November 13, 1999, pp..