Chronic renal failure risk factors: Difference between revisions
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===Comorbidities=== | ===Comorbidities=== | ||
* [[Diabetes]] | * [[Diabetes]] | ||
* | * [[Hypertension]] | ||
* [[Autoimmune diseases]] including [[SLE]], [[scleroderma]], and [[polyarteritis nodosa]] | * [[Autoimmune diseases]] including [[SLE]], [[scleroderma]], and [[polyarteritis nodosa]] | ||
* Multiple myeloma | * Multiple myeloma | ||
* Heart disease | * Heart disease | ||
* [[Smoking]] | * [[Smoking]] | ||
* [[Obesity]] | * [[Obesity]] | ||
* [[Hypercholesterolemia|High cholesterol]] | * [[Hypercholesterolemia|High cholesterol]] | ||
===Renal function=== | |||
* Presence of [[proteinuria]] | |||
* Abnormal urinary sediments | |||
* Structural abnormalities of the urinary tract | |||
* Past history of [[Acute renal failure]] | * Past history of [[Acute renal failure]] | ||
===Genetics=== | ===Genetics=== | ||
* Certain [[DNA]] sequences like allelic versions of [[APOL1]] gene, of the West African ancestry, contributes to a several fold higher risk of some etiologies of [[Chronic renal failure]] e.g [[focal segmental glomerulosclerosis]]. | * Certain [[DNA]] sequences like allelic versions of [[APOL1]] gene, of the West African ancestry, contributes to a several fold higher risk of some etiologies of [[Chronic renal failure]] e.g [[focal segmental glomerulosclerosis]]. | ||
Revision as of 08:24, 14 November 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]
Overview
It is important to identify patients at risk for developing chronic renal disease, even in patients with a normal serum creatinine levels. Chronic renal failure, requiring dialysis or organ transplant, can often be prevented with early detection and treatment.
Risk factors
NSAID use.
Age
- Age 65 or older
Race
- African-American or Hispanics are at increased risk
Family history
- A positive family history increases the risk
Comorbidities
- Diabetes
- Hypertension
- Autoimmune diseases including SLE, scleroderma, and polyarteritis nodosa
- Multiple myeloma
- Heart disease
- Smoking
- Obesity
- High cholesterol
Renal function
- Presence of proteinuria
- Abnormal urinary sediments
- Structural abnormalities of the urinary tract
- Past history of Acute renal failure
Genetics
- Certain DNA sequences like allelic versions of APOL1 gene, of the West African ancestry, contributes to a several fold higher risk of some etiologies of Chronic renal failure e.g focal segmental glomerulosclerosis.