Clostridium difficile infection natural history, complications and prognosis: Difference between revisions

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==Complications==
==Complications==
Fulminant [[colitis]] is an uncommon complication that occurs in 2-3% of patients with ''C. Diff'', and can results in perforation, prolonged [[ileus]], [[megacolon]], and [[death]]. Patients may present with:
*Fulminant [[colitis]] is an uncommon complication that occurs in 2-3% of patients with ''C. Diff'', and can results in perforation, prolonged [[ileus]], [[megacolon]], and [[death]].
* Severe [[abdominal pain]] and distension
* Severe [[diarrhea]]; diarrhea may be absent in patients with ileus
* [[Fever]], [[chills]]
* [[Lethargy]]
* [[Tachycardia]]
* [[Leucocytosis]], up to 40,000 mm3
* [[Metabolic acidosis]]


Toxic megacolon is an enlarged, dilated colon >7cm associated severe systemic toxicity. It may also present with:
*[[Toxic megacolon]] is an enlarged, dilated colon >7cm associated severe systemic toxicity.
* Small intestinal dilation
* Air-fluid levels
* Submucosal [[edema]] resulting in thumb-printing


==References==
==References==

Revision as of 16:54, 20 November 2012

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Complications

  • Fulminant colitis is an uncommon complication that occurs in 2-3% of patients with C. Diff, and can results in perforation, prolonged ileus, megacolon, and death.
  • Toxic megacolon is an enlarged, dilated colon >7cm associated severe systemic toxicity.

References