Guillain-Barré syndrome differential diagnosis

Guillain-Barré syndrome Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Priyamvada Singh, MBBS [2]

Overview

Guillain-Barré syndrome (GBS) is an acute, autoimmune, polyradiculoneuropathy affecting the peripheral nervous system, usually triggered by an acute infectious process. It is included in the wider group of peripheral neuropathies.

Differential diagnosis

Complete Differential Diagnosis of the Causes of Encephalitis

(By organ system)

Cardiovascular	No underlying causes
Chemical / poisoning	No underlying causes
Dermatologic	No underlying causes
Drug Side Effect	No underlying causes
Ear Nose Throat	No underlying causes
Endocrine	No underlying causes
Environmental	No underlying causes
Gastroenterologic	No underlying causes
Genetic	No underlying causes
Hematologic	Vasculitic Neuropathy
Iatrogenic	No underlying causes
Infectious Disease	Botulism, diphtheria, Lyme disease, poliomyelitis, CMV, paresis caused by West Nile fever
Musculoskeletal / Ortho	No underlying causes
Neurologic	Cauda Equina and Conus Medullaris Syndromes, Chronic Inflammatory Demyelinating Polyradiculoneuropathy, Myasthenia Gravis, Multiple Sclerosis, acute myelopathies with chronic back pain and sphincter dysfunction
Nutritional / Metabolic	Metabolic Myopathies, Nutritional Neuropathy,
Obstetric/Gynecologic	No underlying causes
Oncologic	No underlying causes
Opthalmologic	No underlying causes
Overdose / Toxicity	Heavy Metal Toxicity, poisonings with organophosphate, poison hemlock, thallium, or arsenic
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal / Electrolyte	No underlying causes
Rheum / Immune / Allergy
Sexual	No underlying causes
Trauma	No underlying causes
Urologic	No underlying causes
Miscellaneous	porphyria