Congenital rubella syndrome natural history

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Overview

Congenital rubella syndrome causes serious birth defects and the prognosis depends on the severity of the problem. Few defects can be corrected bur neurological damage is permanent.

Complications

CRS can result in serious birth defects such as:

• Malformations of the heart (especially patent ductus arteriosus), eyes or brain
• Deafness
• Spleen, liver or bone marrow problems (some of which may disappear shortly after birth)
• Mental retardation
• Small head size (microcephaly)
• Eye defects
• Low birth weight
• Thrombocytopenic purpura
• Hepatomegaly

Prognosis

• The outcome for a child with congenital rubella depends on the severity of problems present.
• Heart defects can often be corrected.
• Damage to the nervous system is permanent.