Creutzfeldt-Jakob disease other diagnostic studies: Difference between revisions
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Characteristic triphasic spikes | Characteristic triphasic spikes | ||
===Biopsy=== | ===Biopsy=== | ||
In one third of patients with sporadic CJD, deposits of prion protein (scrapie), [[PrpSc|PrP<SUP>Sc</SUP>]], can be found in the skeletal muscle and/or the spleen. Diagnosis of vCJD can be supported by biopsy of the tonsils, which harbour significant amounts of PrpSc; however, [[biopsy]] of brain tissue is the definitive diagnostic test. | In one third of patients with sporadic CJD, deposits of [[prion]] protein (scrapie), [[PrpSc|PrP<SUP>Sc</SUP>]], can be found in the [[skeletal muscle]] and/or the [[spleen]]. Diagnosis of [[vCJD]] can be supported by biopsy of the [[tonsils]], which harbour significant amounts of PrpSc; however, [[biopsy]] of [[brain]] tissue is the definitive diagnostic test. | ||
==References== | ==References== | ||
Revision as of 18:47, 26 December 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Other Diagnostic Studies
Electroencephalography
Characteristic triphasic spikes
Biopsy
In one third of patients with sporadic CJD, deposits of prion protein (scrapie), PrPSc, can be found in the skeletal muscle and/or the spleen. Diagnosis of vCJD can be supported by biopsy of the tonsils, which harbour significant amounts of PrpSc; however, biopsy of brain tissue is the definitive diagnostic test.