Filariasis medical therapy: Difference between revisions
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==Medical Therapy== | ==Medical Therapy== | ||
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Revision as of 05:07, 2 January 2013
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Filariasis Microchapters |
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Treatment |
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Filariasis medical therapy On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Medical Therapy
Different drugs are recommended for the treatment of filariasis depending on the specific causal agent.
Lymphatic Filariasis
- Shown below is a table summarizing the preferred and alternative empiric treatment for Lymphatic filariasis.[1]
| Characteristics of the Patient | Possible Pathogens | Preferred Treatment | Duration of Treatment |
| adults and children > 18 months of age | Wuchereria bancrofti
OR Brugia malayi |
Diethylcarbamazine Citrate
(6mg/kg/day) |
Either a 1 day or 12 day treatment course |
Onchocerciasis
- Shown below is a table summarizing the preferred and alternative empiric treatment for Onchocerciasis[2]
| Characteristics of the Patient | Possible Pathogens | Preferred Treatment | Duration of Treatment | Alternative Treatment |
| Adult | Onchocerca volvulus (microfilariae) | Ivermectin
150 mcg/kg orally in one dose |
Every 6 months | Doxycycline
200 mg orally daily for 6 weeks |
| Pediatric | Onchocerca volvulus (microfilariae) | Ivermectin
150 mcg/kg orally in one dose |
Every 6 months | Doxycycline
200 mg orally daily for 6 weeks |
Loa Loa Filariasis
- Shown below is a table summarizing the preferred treatment for Loa loa filariasis[3]
| Characteristics of the Patient | Possible Pathogens | Preferred Treatment | Duration of Treatment |
| Symptomatic loiasis with MF/mL <8,000 | Loa loa | Diethylcarbamazine (DEC)
8–10 mg/kg orally in 3 divided doses daily |
For 21 days |
| Symptomatic loiasis, with MF/mL <8,000 and failed 2 rounds DEC
OR Symptomatic loiasis, with MF/ml ≥8,000 to reduce level to <8,000 prior to treatment with DEC |
Loa loa | Albendazole
200 mg orally twice daily |
For 21 days |
| Symptomatic loiasis, with MF/mL ≥8,000 | Apheresis* followed by DEC | N/A | N/A |
(*)Apharesis should be performed at an institution with experience in using this therapeutic modality for loiasis.