Purpura classification: Difference between revisions

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Revision as of 14:39, 21 February 2013

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 {{Purpura}}
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-==Classification==
-Purpura is a common and unspecific symptom, however the underlying mechanism commonly involves one of the following:
-*[[Platelet|Platelet disorders]]
-**[[idiopathic thrombocytopenic purpura|Primary thrombocytopenic purpura]]
-**Secondary thrombocytopenic purpura
-*Vascular disorders
-**Microvascular injury, as seen in senile (old age) purpura, when blood vessels are more easily damaged
-**Hypertensive states
-**Deficient vascular support
-**[[Vasculitis]], as in the case of [[Henoch-Schönlein purpura]]
-*[[Coagulopathy|Coagulation disorders]]
-**[[Disseminated intravascular coagulation]] (DIC)
-There are also cases of psychogenic purpura described in the medical literature,<ref name="pmid10069314">{{cite journal |author=Anderson JE, DeGoff W, McNamara M |title=Autoerythrocyte sensitization (psychogenic purpura): a case report and review of the literature |journal=Pediatric emergency care |volume=15 |issue=1 |pages=47-8 |year=1999 |pmid=10069314 |doi=}}</ref> some claimed to be due to "autoerythrocyte sensitization". Other studies<ref name="pmid8340191">{{cite journal |author=Lotti T, Benci M, Sarti MG, Teofoli P, Senesi C, Bonan P, et al. |title=Psychogenic purpura with abnormallt cutaney increased tPA dependeny |journous fibrinolytic activital=Int J Dermatol |volume=32| issue=7 |pages=521-3 |year=1993 |pmid=8340191 |doi=}}</ref> suggest, that local (cutaneous) activity of [[tPA]] can be increased in psychogenic purpura, leading to substantial amounts of localized plasmin activity, rapid degradation of fibrin clots, and resultant bleeding.
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Purpura classification: Difference between revisions

Revision as of 14:39, 21 February 2013

References

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