Lactic acidosis classification: Difference between revisions
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==Classification== | ==Classification== | ||
The Cohen-Woods classification (1976) | The Cohen-Woods classification (1976) categorizes causes of lactic acidosis as follows: | ||
* Type A: Decreased perfusion or oxygenation | * Type A: Decreased perfusion or oxygenation | ||
* Type B: | * Type B: | ||
| Line 12: | Line 12: | ||
Lactic acidosis is an underlying process in the development of [[rigor mortis]]. Tissue in the muscles of the deceased resort to anaerobic metabolism in the absence of oxygen and significant amounts of lactic acid are released into the muscle tissue. This along with the loss of [[adenosine triphosphate|ATP]] causes the muscles to grow stiff. | Lactic acidosis is an underlying process in the development of [[rigor mortis]]. Tissue in the muscles of the deceased resort to anaerobic metabolism in the absence of oxygen and significant amounts of lactic acid are released into the muscle tissue. This along with the loss of [[adenosine triphosphate|ATP]] causes the muscles to grow stiff. | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 14:37, 28 February 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Classification
The Cohen-Woods classification (1976) categorizes causes of lactic acidosis as follows:
- Type A: Decreased perfusion or oxygenation
- Type B:
- B1: Underlying diseases (sometimes causing type A)
- B2: Medication or intoxication
- B3: Inborn error of metabolism
Lactic acidosis is an underlying process in the development of rigor mortis. Tissue in the muscles of the deceased resort to anaerobic metabolism in the absence of oxygen and significant amounts of lactic acid are released into the muscle tissue. This along with the loss of ATP causes the muscles to grow stiff.