Fatty liver causes: Difference between revisions
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{{CMG}} | {{CMG}} | ||
==Causes == | ==Causes == | ||
===Common Causes=== | |||
Fatty liver is commonly associated with [[alcohol]] or [[metabolic syndrome]] ([[diabetes]], [[hypertension]] and [[dyslipidemia]]) but can also be due to any one of many causes:<ref name="angulo">{{cite journal |author=Angulo P |title=Nonalcoholic fatty liver disease |journal=N. Engl. J. Med. |volume=346 |issue=16 |pages=1221-31 |year=2002 |pmid=11961152 |doi=10.1056/NEJMra011775}}</ref><ref name="bayard">{{cite journal |author=Bayard M, Holt J, Boroughs E |title=Nonalcoholic fatty liver disease |journal=American family physician |volume=73 |issue=11 |pages=1961-8 |year=2006 |pmid=16770927 |doi=}}</ref> | Fatty liver is commonly associated with [[alcohol]] or [[metabolic syndrome]] ([[diabetes]], [[hypertension]] and [[dyslipidemia]]) but can also be due to any one of many causes:<ref name="angulo">{{cite journal |author=Angulo P |title=Nonalcoholic fatty liver disease |journal=N. Engl. J. Med. |volume=346 |issue=16 |pages=1221-31 |year=2002 |pmid=11961152 |doi=10.1056/NEJMra011775}}</ref><ref name="bayard">{{cite journal |author=Bayard M, Holt J, Boroughs E |title=Nonalcoholic fatty liver disease |journal=American family physician |volume=73 |issue=11 |pages=1961-8 |year=2006 |pmid=16770927 |doi=}}</ref> | ||
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*Drugs and toxins: [[Amiodarone]], [[methotrexate]], [[diltiazem]], [[highly active antiretroviral therapy]], [[glucocorticoids]], [[tamoxifen]], environmental [[hepatotoxin]]s (e.g. [[phosphorus]], toxic [[mushroom]]) | *Drugs and toxins: [[Amiodarone]], [[methotrexate]], [[diltiazem]], [[highly active antiretroviral therapy]], [[glucocorticoids]], [[tamoxifen]], environmental [[hepatotoxin]]s (e.g. [[phosphorus]], toxic [[mushroom]]) | ||
*Other: [[Inflammatory bowel disease]], [[HIV]] | *Other: [[Inflammatory bowel disease]], [[HIV]] | ||
===Causes by Organ System=== | |||
===Causes in Alphabetical Order=== | |||
{{MultiCol}} | |||
*[[3-alpha-hydroxyacyl-CoA dehydrogenase deficiency]] | |||
*[[Abetalipoproteinaemia]] | |||
*[[Acute fatty liver of pregnancy]] | |||
*[[Alcohol]] | |||
*[[Alpha1-antitrypsin deficiency]] | |||
*[[Amiodarone]] | |||
*[[Anti retroviral therapy]] | |||
*[[Autoimmune hepatitis]] | |||
*[[Carbon tetrachloride]] | |||
*[[Chanarin-Dorfman disease]] | |||
*[[Citrullinemia type 2]] | |||
*[[Congenital generalized lipodystrophy type 1]] | |||
*[[Congenital generalized lipodystrophy type 2]] | |||
*[[Cystic fibrosis]] | |||
*[[Diabetes mellitus]] | |||
*[[Diltiazem]] | |||
*[[Ethanol]] | |||
*[[Familial combined hyperlipidemia]] | |||
*[[Fructose-1, 6-diphosphatase deficiency]] | |||
*[[Galactosemia]] | |||
*[[Gastric bypass]] | |||
*[[Glucocorticoids]] | |||
*[[Glycogen storage disorders]] | |||
*[[Hepatitis C]] | |||
*[[HIV]] | |||
*[[Hypertriglyceridemia]] | |||
*[[Hypobetalipoproteinemia]] | |||
*[[Inflammatory bowel disease]] | |||
*[[Iron overload]] | |||
{{ColBreak}} | |||
*[[Jejunal diverticulosis with bacterial overgrowth]] | |||
*[[Jejunoileal bypass]] | |||
*[[Kwashiorkor]] | |||
*[[Lipodystrophy]] | |||
*[[Lomitapide]] | |||
*[[Long-chain acyl-CoA dehydrogenase deficiency]] | |||
*[[Malnutrition]] | |||
*[[Medium chain acyl-CoA dehydrogenase deficiency]] | |||
*[[Metabolic syndrome]] | |||
*[[Methotrexate]] | |||
*[[Mipomersen]] | |||
*[[Mushroom poisoning]] | |||
*[[Neutral lipid storage disease with myopathy]] | |||
*[[Non alcoholic steatohepatitis]] | |||
*[[Obesity]] | |||
*[[Overnutrition]] | |||
*[[Patent ductus venosus]] | |||
*[[Phosphorous]] | |||
*[[Refeeding syndrome]] | |||
*[[Severe weight loss]] | |||
*[[Tamoxifen]] | |||
*[[Tetracycline]] | |||
*[[Total parenteral nutrition]] | |||
*[[Type II diabetes]] | |||
*[[Tyrosinemia]] | |||
*[[Valproic acid]] | |||
*[[Very long-chain acyl-CoA dehydrogenase deficiency]] | |||
*[[Weber-Christian disease]] | |||
*[[Wilson disease]] | |||
{{EndMultiCol}} | |||
==References== | ==References== |
Revision as of 14:01, 1 April 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Causes
Common Causes
Fatty liver is commonly associated with alcohol or metabolic syndrome (diabetes, hypertension and dyslipidemia) but can also be due to any one of many causes:[1][2]
- Metabolic: Abetalipoproteinemia, glycogen storage diseases, Weber-Christian disease, Wolmans disease, acute fatty liver of pregnancy, lipodystrophy
- Nutritional: Malnutrition, total parenteral nutrition, severe weight loss, refeeding syndrome, jejuno-ileal bypass, gastric bypass, jejunal diverticulosis with bacterial overgrowth
- Drugs and toxins: Amiodarone, methotrexate, diltiazem, highly active antiretroviral therapy, glucocorticoids, tamoxifen, environmental hepatotoxins (e.g. phosphorus, toxic mushroom)
- Other: Inflammatory bowel disease, HIV
Causes by Organ System
Causes in Alphabetical Order