Primary biliary cirrhosis laboratory findings: Difference between revisions
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===Laboratory Findings=== | |||
To diagnose PBC, distinctions should be established from other conditions with similar symptoms, such as [[autoimmune hepatitis]] or [[primary sclerosing cholangitis]] (PSC). | |||
Diagnostic [[blood test]]s include: | |||
* Deranged [[liver function test]]s (high [[alkaline phosphatase]], elevated AST, ALT) | |||
* Presence of certain [[antibodies]]: [[Anti-mitochondrial antibody|antimitochondrial antibody]] [[antinuclear antibody|antinuclear antibodies]] like [[Anti-glycoprotein-210 antibodies]], [[Anti-centromere antibodies]], anti-sp100. (the M2-[[IgG]] antimitochondrial antibody is the most specific test) | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
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[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Needs | [[Category:Needs overview]] |
Revision as of 19:51, 16 April 2013
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Primary Biliary Cirrhosis Microchapters |
Differentiating Primary Biliary Cirrhosis from other Diseases |
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Laboratory Findings
To diagnose PBC, distinctions should be established from other conditions with similar symptoms, such as autoimmune hepatitis or primary sclerosing cholangitis (PSC).
Diagnostic blood tests include:
- Deranged liver function tests (high alkaline phosphatase, elevated AST, ALT)
- Presence of certain antibodies: antimitochondrial antibody antinuclear antibodies like Anti-glycoprotein-210 antibodies, Anti-centromere antibodies, anti-sp100. (the M2-IgG antimitochondrial antibody is the most specific test)