Primary biliary cirrhosis other diagnostic studies: Difference between revisions
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===Liver Biopsy=== | ===Liver Biopsy=== | ||
Primary biliary cirrhosis is characterized by interlobular bile duct destruction. [[Histopathologic]] findings of primary biliary cirrhosis include:<ref name=pmid10976014>{{cite journal | pmid = 10976014 | doi=10.1053/bega.2000.0103 | volume=14 | issue=4 | title=Destruction of bile ducts in primary biliary cirrhosis | year=2000 | month=August | author=Nakanuma Y, Tsuneyama K, Sasaki M, Harada K | journal=Baillieres Best Pract Res Clin Gastroenterol | pages=549–70}}</ref> | Primary biliary cirrhosis is characterized by interlobular bile duct destruction. [[Histopathologic]] findings of primary biliary cirrhosis include:<ref name=pmid10976014>{{cite journal | pmid = 10976014 | doi=10.1053/bega.2000.0103 | volume=14 | issue=4 | title=Destruction of bile ducts in primary biliary cirrhosis | year=2000 | month=August | author=Nakanuma Y, Tsuneyama K, Sasaki M, Harada K | journal=Baillieres Best Pract Res Clin Gastroenterol | pages=549–70}}</ref> | ||
*Inflammation of the bile ducts, characterized by intraepithelial [[lymphocyte]]s | *Inflammation of the bile ducts, characterized by intraepithelial [[lymphocyte]]s | ||
*Periductal [[epithelioid]] [[granulomata]] | *Periductal [[epithelioid]] [[granulomata]] | ||
A liver biopsy is necessary to determine the stage of disease. | A liver biopsy is necessary to determine the stage of disease. | ||
===ERCP=== | ===ERCP=== | ||
Abdominal [[medical ultrasonography|ultrasound]] or a [[CT scan]] is usually performed to rule out blockage to the bile ducts. Previously most suspected sufferers underwent a [[liver biopsy]], and - if uncertainty remained - [[endoscopic retrograde cholangiopancreatography]] (ERCP, an [[endoscopy|endoscopic]] investigation of the [[bile duct]]). | Abdominal [[medical ultrasonography|ultrasound]] or a [[CT scan]] is usually performed to rule out blockage to the bile ducts. Previously most suspected sufferers underwent a [[liver biopsy]], and - if uncertainty remained - [[endoscopic retrograde cholangiopancreatography]] (ERCP, an [[endoscopy|endoscopic]] investigation of the [[bile duct]]). | ||
Revision as of 20:21, 16 April 2013
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Other Diagnostic Studies
Liver Biopsy
Primary biliary cirrhosis is characterized by interlobular bile duct destruction. Histopathologic findings of primary biliary cirrhosis include:[1]
- Inflammation of the bile ducts, characterized by intraepithelial lymphocytes
- Periductal epithelioid granulomata
A liver biopsy is necessary to determine the stage of disease.
ERCP
Abdominal ultrasound or a CT scan is usually performed to rule out blockage to the bile ducts. Previously most suspected sufferers underwent a liver biopsy, and - if uncertainty remained - endoscopic retrograde cholangiopancreatography (ERCP, an endoscopic investigation of the bile duct).