Eosinophilia causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Template:GCC

Causes

Common Causes

• Adrenal insufficiency
• Asthma
• Atheroembolic disease
• Atopic dermatitis
• Fungal infections
• Hypereosinophilic syndromes
• Immunodeficiency states
• Leukemia
• Lymphoma
• Mastocytosis
• Medication-related eosinophilia
• Parasitic infections
• Rhinitis syndromes
• Vasculitis

Causes by Organ System

Cardiovascular	Endomyocardial fibrosis, Cholesterol embolism, Loeffler endocarditis , Eosinophilic myocarditis
Chemical / poisoning	No underlying causes
Dermatologic	Erythema multiforme, Atopic dermatitis, Dermatitis herpetiformis, Eosinophilic fasciitis, Eosinophilic pustular folliculitis, Pemphigus vulgaris, Psoriasis, Systemic lupus erythematosus, Sarcoptes scabiei, Eczema , Exfoliative dermatitis , Urticaria , Eosinophilic panniculitis , Shulman’s syndrome , Stevens - Johnson syndrome , Duhring disease , Histiositosis with cutaneous involvement
Drug Side Effect	Sulphonamides, Allopurinol, Amitriptyline, Capreomycin, Caspofungin, Chlorpropamide, Clomipramine, Daptomycin, Desipramine, Dothiepin, Doxycycline, Enfuvirtide, Etravirine, Gold salts, Granulocyte-macrophage colony stimulating factor, Hydralazine, Imipramine, Interleukin 2, Micafungin, Minocycline, Nalidixic acid, Nitrofurantoin, Nortriptyline, Olanzapine, Oxytetracycline, Pentostatin, Procarbazine, Tobacco smoking, Tryptophan, Vancomycin, Aldesleukin , Amikacin Sulfate , Capastat Sulfate , Capreomycin Sulfate , Cefotaxime Sodium , Cefoxitin Sodium , Ceftazidime , Cefuroxime , LyphocinMaolate
Ear Nose Throat	No underlying causes
Endocrine	Adrenal cortex insufficiency, Addisons disease , Adrenocortical insufficiency
Environmental	An allergic reaction to an environmental antigen
Gastroenterologic	Inflammatory Bowel Disease , Cirrhosis of liver , Chronic active hepatitis , Eosinophilic Gastroenteritis , Peritoneal dialysis
Genetic	Autoimmune lymphoproliferative syndrome type 1, Autoimmune lymphoproliferative syndrome type 2, Familial eosinophilia, Kostmann disease, Omenn syndrome, Wiskott-Aldrich syndrome, TAR syndrome, kostmann syndrome, Chromosome 21 partial deletion
Hematologic	Acute lymphoblastic leukemia, Chronic myeloid leukaemia, Hodgkin lymphoma, Thrombocytopenia with absent radii , Familial reticuloendotheliosis with eosinophilia
Iatrogenic	Radiotherapy
Infectious Disease	Acanthocheilonemiasis, Alveolar hydatid disease, Ancylostoma caninum, Ancylostoma duodenale, Angiostrongyliasis, Anisakiasis, Ascariasis, Capillaria, Clonorchiasis, Coccidioidomycosis, Dicrocoelium dendriticum fluke, Dracunculiasis, Echinococcus granulosus, Fasciola hepatica, Gnathostomiasis, Heterophyiasis, Lepromatous leprosy, Loa loa filariasis, Lymphatic filariasis, Mansonelliasis, Metagonimiasis, Mycobacterium tuberculosis, Onchocerciasis, Opisthorchiasis, Paragonimiasis, Schistosoma haematobium, Schistosoma mansoni, Strongyloidiasis, Toxocariasis, Trichinella spiralis, Pneumocystis jirovecii infection , Visceral larva migrans , Brucellosis , Cat-scratch fever , Chlamydial pneumonia of infancy , Infectious lymphocytosis , Infectious mononucleosis , Scarlet fever, Amebiasis , Malaria
Musculoskeletal / Ortho	Polyarteritis nodosa, Polymyositis, Rheumatoid disease, Dressler's syndrome , Eosinophilic fasciitis , Idiopathic eosinophilic synovitis , Progressive systemic sclerosis (scleroderma) , SLE , Sjögren's syndrome , Sarcoidosis , Eosinophilia – Myalgia syndrome , Dermatomyositis
Neurologic	No underlying causes
Nutritional / Metabolic	No underlying causes
Obstetric/Gynecologic	No underlying causes
Oncologic	Acute lymphoblastic leukemia, Chronic myeloid leukaemia, Hodgkin lymphoma, Immunoblastic lymphadenopathy , Sarcomas and carcinomas of ovary, Carcinoma of pancreas , Carcinoma of lung , Carcinoma of colon, Carcinoma of cervix , Acute eosinophilic leukemia , Chronic eosinophilic leukemia , Brain tumors
Opthalmologic	No underlying causes
Overdose / Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	Simple pulmonary eosinophilia, Visceral larva migrans, Allergic bronchopulmonary aspergillosis, Extrinsic allergic alveolitis, Tropical pulmonary eosinophilia, Churg-Strauss syndrome, Bronchial asthma, Allergic Rhinitis, Chronic eosinophilic pneumonia , Occupational lung diseases , Idiopathic eosinophilic chronic pneumopathy , Magrassi- Leonardi syndrome
Renal / Electrolyte	Interstitial nephritis, Eosinophilic cystitis , Hemodialysis , CRF not on renal replacement therapy , Diffuse proliferative glomerular nephritis , Thrombotic thrombocytopenic purpura , Renal cell carcinoma
Rheum / Immune / Allergy	Eosinophilia-myalgia syndrome,Hyper-IgE syndrome , IgA deficiency , Wiskott-Aldrich syndrome ,Graft versus host immunologic reactions ,Milk protein allergy , Omenn syndrome , Severe congenital Neutropenia
Sexual	No underlying causes
Trauma	No underlying causes
Urologic	No underlying causes
Miscellaneous	Angiolymphoid hyperplasia with eosinophilia, Eosinophilic cellulitis, Hypereosinophilic syndrome, Kimura disease, Familial eosinophilia , Episodic angioedema with eosinophilia , Aggressive systemic mastocytosis

Causes in Alphabetical Order

Acanthocheilonemiasis Acute eosinophilic leukemia Acute lymphoblastic leukemia Acute myeloid leukemia Addison's disease Adrenocortical insufficiency Aggressive systemic mastocytosis Aldesleukin Alfotax Allergic bronchopulmonary aspergillosis Allergic inflammation Allergic rhinitis Allopurinol Alveolar hydatid disease Amebiasis Amikacin sulfate Amikafur Amikayect Amikin Amitriptyline Ampicillin Ancylostoma caninum Ancylostoma duodenale Angiolymphoid hyperplasia with eosinophilia Angiostrongyliasis costaricensis Anisakiasis Anthelmintic Ascariasis Aspergillosis Aspirin Asthma Atheroembolic disease Atopic and related diseases Atopic dermatitis Auranofin Autoimmune lymphoproliferative syndrome type 1 Autoimmune lymphoproliferative syndrome type 2 Aztreonam B cell non-Hodgkin lymphoma Baylisascaris infection Benaxima Besnier-Boeck-Schaumann disease Beta blockers Biclin Biosint Brain tumors Bronchial asthma Brucellosis Buerger's disease Capastat sulfate Capillaria Capreomycin sulfate Capreomycin Carbamazepine Carcinoma especially with radiation therapy Caspofungin Cat-scratch fever Cefaclor Cefaxim Cefizox Cefoclin Cefotaxime sodium Cefoxitin sodium Ceftazidime Ceftazim Ceftin Ceftizoxime Cefuroxime Cephalosporin Ceptaz Chlamydial pneumonia of infancy Chlorphenesin carbamate Chlorpropamide Cholesterol embolism Chromosome 21 partial deletion Chronic eosinophilic leukemia Chronic active hepatitis Chronic eosinophilic leukemia Chronic eosinophilic pneumonia Chronic myeloid leukaemia Churg-Strauss syndrome Cirrhosis Claforan Clofibrate Clomipramine Clonorchis sinensis Coccidioidomycosis Connective tissue disease Cysticercosis Cytomegalovirus Dantrolene Dapsone Daptomycin Dermatitis herpetiformis Dermatomyositis Desipramine Dicrocoelium dendriticum fluke Dientamoeba fragilis Diethylcarbamazine Diffuse proliferative glomerular nephritis Dothiepin

Doxycycline Dracunculiasis Dressler's syndrome Duhring's disease Echinococcosis Echinococcus granulosus Echinococcus Eczema Endomyocardial fibrosis Enfuvirtide Eosinophilia-myalgia syndrome Eosinophilic cellulitis Eosinophilic cystitis Eosinophilic fasciitis Eosinophilic folliculitis Eosinophilic gastroenteritis Eosinophilic granuloma Eosinophilic leukemia Eosinophilic myocarditis Eosinophilic panniculitis Eosinophilic pneumonia Eosinophilic pulmonary syndrome Eosinophilic pustular folliculitis Episodic angioedema with eosinophilia Erythema multiforme Ethosuximide Etravirine Exfoliative dermatitis Extrinsic allergic alveolitis Familial eosinophilia Familial reticuloendotheliosis with eosinophilia Farmer's lung Fasciola hepatica Fascioliasis Fasciolopsis buski Filariases Flukes Food allergy Fortaz Fortum Fotexina Froxal Fungal infections Gamikal GM-CSF Gnathostoma hispidum Gnathostoma spinigerum Gnathostomiasis Gold salts Graft versus host immunologic reactions Granulocyte-macrophage colony stimulating factor Helminth infections Hemodialysis Heterophyiasis Histiositosis with cutaneous involvement Hodgkin lymphoma Hookworm infection human T-lymphotropic virus (HTLV)-I human T-lymphotropic virus (HTLV)-II Hydralazine Hyper-IgE syndrome Hypereosinophilic syndrome Hypersensitivity Hypoadrenalism Idiopathic eosinophilic chronic pneumopathy Idiopathic eosinophilic synovitis IgA deficiency Imipramine Immunoblastic lymphadenopathy Infectious lymphocytosis Infectious mononucleosis Inflammatory Bowel Disease Interleukin-2 Interstitial nephritis Isospora belli Kefurox Ketorolac Kimura disease Kostmann disease Kostmann syndrome L-tryptophan contaminant Lepromatous leprosy Leukemia Loa loa Loeffler endocarditis Loeffler's syndrome Lymphomas Lyphocin maolate Magrassi-Leonardi syndrome Malaria Malignancy Mansonella ozzardi Mansonelliasis Maolate Mastocytosis Medication-related eosinophilia Mefoxin Metagonimiasis Micafungin Milk protein allergy

Minocycline Modafinil Mycobacterium tuberculosis Myeloproliferative disorders Nalidixic acid Nasal polyposis Nitrofurantoin Nonallergic rhinitis with eosinophilia syndrome (NARES) Nonsteroidal antiinflammatory agents Nortriptyline NSAID nephropathy Occupational lung diseases Ocular larva migrans Olanzapine Omenn syndrome Onchocerciasis Opisthorchiasis Oxytetracycline Papaverine Paragonimiasis Paraneoplastic syndrome Parasitic infection Pemphigus vulgaris Penicillin Pentostatin Peritoneal dialysis Phenytoin Pneumocystis jirovecii Polyarteritis nodosa Polymyositis Praziquantel Precursor B-cell acute lymphoblastic leukemia with t(5;14) Precursor T-cell lymphoblastic lymphoma with t(8;13) Primary sclerosing cholangitis Procarbazine Progressive systemic sclerosis Proleukin Psoriasis Pulmonary eosinophilia Pyrimethamine Radiotherapy Ranitidine Renal cell carcinoma Rheumatoid arthritis Rice millers syndrome River Blindness Sarcoidosis Sarcoptes scabiei Scabies Scarlet fever Schistosoma haematobium Schistosoma mansoni Selective serotonin reuptake inhibitor Shulman’s syndrome Simple pulmonary eosinophilia Sjögren's syndrome Spirometra erinace-ieuropaei Spirometra mansoni Spirometra mansonoides Spirometra theileri Stevens-Johnson syndrome Strongyloidiasis Sulphonamides Systemic lupus erythematosus Systemic mastocytosis Tagal Taloken Tapeworms Taporin TAR syndrome Tazicef Tazidime Tetracyclines Thrombocytopenia with absent radii Thrombotic thrombocytopenic purpura Thymoma Tissue invasion by parasites Tobacco smoking Toxic oil syndrome Toxocara canis Toxocariasis Transplant rejection Trichinella spiralis Tropical pulmonary eosinophilia Tryptophan Urticaria Vancoled Vancomycin Hydrochloride Vancomycin Vasculitis Viken Visceral larva migrans Waytrax Wegener granulomatosis White blood cells Wiskott-Aldrich syndrome Wuchereria bancrofti Yectamid Zimelidine Zinacef