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{|style="width:82%; height:100px" border="1"
{|style="width:82%; height:100px" border="1"
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Allergic vasculitis]],  [[anemia]],  [[aneurysm]],  [[angiosarcoma]],  arterial [[dysplasia]],  [[arterial insufficiency]],  [[arterial thrombosis]],  [[arterio-venous malformation]],  arteriovenous [[fistulas]],  [[arteriovenous malformation]],  [[atheroma]],  [[atherosclerosis]],  [[cholesterol embolism]],  chronic [[venous insufficiency]],  [[Churg-Strauss syndrome]],  [[congestive heart failure]],  [[deep vein thrombosis]],  [[dehydration]],  [[diabetes mellitus]],  [[embolism]],  [[heart failure]],  [[hypertension]],  [[hypotension]],  [[hypothermia]],  [[kaposi's sarcoma]],  [[leukocytoclastic vasculitis]],  [[livedoid vasculopathy]],  [[lymphangitis]],  [[lymphatic obstruction]],  lymphatic vessel [[dysplasia]],  [[lymphedema]],  [[peripheral artery disease]],  [[polyarteritis nodosa]],  [[polyarteritis]],  [[post thrombotic syndrome]],  [[raynaud's syndrome]],  [[sepsis ]],  [[septic emboli]],  [[thromboangiitis obliterans]],  [[thrombotic thrombocytopenic purpura]],  [[varicose veins]],  [[vasculitis]],  venous [[dysplasia]],  [[Wegener's granulomatosis]]
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Allergic vasculitis]],  [[anemia]],  [[aneurysm]],  [[angiosarcoma]],  arterial [[dysplasia]],  [[arterial insufficiency]],  [[arterial thrombosis]],  [[arterio-venous malformation]],  arteriovenous [[fistulas]],  [[arteriovenous malformation]],  [[atheroma]],  [[atherosclerosis]],  [[cholesterol embolism]],  chronic [[venous insufficiency]],  [[Churg-Strauss syndrome]],  [[congestive heart failure]],  [[deep vein thrombosis]],  [[dehydration]],  [[diabetes mellitus]],  [[embolism]],  [[heart failure]],  [[hypertension]],  [[hypotension]],  [[hypothermia]],  [[kaposi's sarcoma]],  [[leukocytoclastic vasculitis]],  [[livedoid vasculopathy]],  [[lymphangitis]],  [[lymphatic obstruction]],  lymphatic vessel [[dysplasia]],  [[lymphedema]],  [[peripheral artery disease]],  [[polyarteritis nodosa]],  [[polyarteritis]],  [[post thrombotic syndrome]],  [[raynaud's syndrome]],  [[sepsis ]],  [[septic emboli]],  [[thromboangiitis obliterans]],  [[thrombotic thrombocytopenic purpura]],  [[varicose veins]],  [[vasculitis]],  venous [[dysplasia]],  [[venous valvular incompetence]],  [[Wegener's granulomatosis]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Chemical/Poisoning'''
| '''Chemical/Poisoning'''
|bgcolor="Beige"| [[Arsenic]]
|bgcolor="Beige"| [[Arsenic]],  [[noxious chemicals]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Dermatologic'''
| '''Dermatologic'''
|bgcolor="Beige"| [[Actinic keratosis]],  [[advanced age]],  [[allergic vasculitis]],  [[amoebiasis]] cutis,  [[contact dermatitis]],  [[continuous trauma]],  [[Crohn's disease]],  [[decubitus ulcer]],  [[ecthyma]],  [[erysipelas]],  [[Bazin disease | erythema induratum of bazin]],  [[filariasis]],  [[furuncle]],  [[glanders]],  [[herpes simplex]],  [[incontinence]],  [[keratoacanthoma]],  [[lymphoma]] ulcers,  [[Eumycetoma | madura foot]],  [[melanoma]],  [[acquired perforating dermatosis]],  [[porphyria cutanea tarda]],  [[prolonged immobilization]],  radiation [[dermatitis]],  [[sporotrichosis]],  [[squamous cell carcinoma]],  [[ulcerative colitis]],  [[xeroderma pigmentosum]]  
|bgcolor="Beige"| [[Actinic keratosis]],  [[advanced age]],  [[allergic vasculitis]],  [[amoebiasis]] cutis,  [[contact dermatitis]],  [[continuous trauma]],  [[Crohn's disease]],  [[decubitus ulcer]],  [[Impetigo | ecthyma]],  [[erysipelas]],  [[Bazin disease | erythema induratum of bazin]],  [[filariasis]],  [[furuncle]],  [[glanders]],  [[herpes simplex]],  [[incontinence]],  [[keratoacanthoma]],  [[lymphoma]] ulcers,  [[Eumycetoma | madura foot]],  [[melanoma]],  [[acquired perforating dermatosis]],  [[porphyria cutanea tarda]],  [[prolonged immobilization]],  radiation [[dermatitis]],  [[sporotrichosis]],  [[squamous cell carcinoma]],  [[ulcerative colitis]],  [[xeroderma pigmentosum]]  
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
| '''Drug Side Effect'''
|bgcolor="Beige"| [[Coumarin]],  [[ergotamine]],  [[Chemotherapy | extravasated cytostatic agents]],  [[halogens]],  [[hydroxyurea]],  [[leflunomide]],  [[methotrexate]],  [[penicillin]],  [[plasmin]],  [[plasminogen activator inhibitor-1]],  [[tissue plasminogen activator]]  
|bgcolor="Beige"| [[Coumarin]],  [[ergotamine]],  extravasated [[Chemotherapy | cytostatic agents]],  [[halogens]],  [[hydroxyurea]],  [[leflunomide]],  [[methotrexate]],  [[penicillin]],  [[plasmin]],  [[plasminogen activator inhibitor-1]],  [[tissue plasminogen activator]]  
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Genetic'''
| '''Genetic'''
|bgcolor="Beige"| Arterial [[dysplasia]],  [[factor V Leiden mutation]],  [[gaucher's disease]],  [[hereditary spherocytosis]],  [[klinefelter syndrome]],  [[leukocyte adhesion deficiency]],  lymphatic vessel [[dysplasia]],  [[prolidase deficiency]],  [[thalassaemia]],  venous [[dysplasia]],  [[xeroderma pigmentosum]]  
|bgcolor="Beige"| Arterial [[dysplasia]],  [[factor V Leiden mutation]],  [[gaucher's disease]],  [[hereditary spherocytosis]],  [[klinefelter syndrome]],  [[leukocyte adhesion deficiency]],  lymphatic vessel [[dysplasia]],  [[prolidase deficiency]], [[tap1 mutation]],  [[thalassaemia]],  venous [[dysplasia]],  [[xeroderma pigmentosum]]  
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Infectious Disease'''
| '''Infectious Disease'''
|bgcolor="Beige"| [[Actinomycosis]],  [[amoebiasis]] cutis,  [[amoebiasis]],  [[anthrax]],  [[bacillary angiomatosis]],  [[bacterial infection]],  [[bacteroides]],  [[blastomycosis]],  [[borrelia vincenti]],  [[cellulitis]],  [[coccidiomycosis]],  [[cold agglutinin disease]],  [[diphtheria]],  [[ecthyma gangrenosum ]],  [[ecthyma]],  [[erysipelas]],  [[fasciitis necroticans ]],  [[filariasis]],  [[folliculitis]],  [[francisella tularensis]],  [[furuncle]],  [[gas gangrene ]],  [[glanders]],  [[granuloma inguinale]],  [[haemophilus ducreyi]],  [[herpes simplex]],  [[histoplasmosis]],  [[kala-azar]],  [[leishmaniasis]],  [[leprosy]],  [[lues maligna]],  [[lymphangitis]],  [[Eumycetoma | madura foot]],  [[mycobacterium ulcerans]],  [[mycosis fungoides]],  [[osteomyelitis]],  [[papillomatosis cutis carcinoides]],  [[poliomyelitis]],  [[rodent ulcer]],  [[sepsis ]],  [[septic emboli]],  [[sporotrichosis]],  [[syphilis]],  [[tinea pedis]],  [[tropical ulcer]],  [[tuberculosis]],  [[tularemia]],  [[ulcerative pyoderma]],  [[variola virus]],  [[vasculitis]],  [[yaws]]
|bgcolor="Beige"| [[Actinomycosis]],  [[amoebiasis]] cutis,  [[amoebiasis]],  [[anthrax]],  [[bacillary angiomatosis]],  [[bacterial infection]],  [[bacteroides]],  [[blastomycosis]],  [[borrelia vincenti]],  [[cellulitis]],  [[coccidiomycosis]],  [[cold agglutinin disease]],  [[diphtheria]],  [[ecthyma gangrenosum ]],  [[Impetigo | ecthyma]],  [[erysipelas]],  [[fasciitis necroticans ]],  [[filariasis]],  [[folliculitis]],  [[francisella tularensis]],  [[furuncle]],  [[gas gangrene ]],  [[glanders]],  [[granuloma inguinale]],  [[haemophilus ducreyi]],  [[herpes simplex]],  [[histoplasmosis]],  [[kala-azar]],  [[leishmaniasis]],  [[leprosy]],  [[lues maligna]],  [[lymphangitis]],  [[Eumycetoma | madura foot]],  [[mycobacterium ulcerans]],  [[mycosis fungoides]],  [[osteomyelitis]],  [[papillomatosis cutis carcinoides]],  [[poliomyelitis]],  [[rodent ulcer]],  [[sepsis ]],  [[septic emboli]],  [[sporotrichosis]],  [[syphilis]],  [[tinea pedis]],  [[tropical ulcer]],  [[tuberculosis]],  [[tularemia]],  [[ulcerative pyoderma]],  [[variola virus]],  [[vasculitis]],  [[yaws]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Rheumatology/Immunology/Allergy'''
| '''Rheumatology/Immunology/Allergy'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Rheumatoid arthritis]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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{{col-begin|width=85%}}
{{col-begin|width=85%}}
{{col-break|width=33%}}
{{col-break|width=33%}}
*[[Acquired perforating dermatosis]]
*[[Actinic keratosis]]
*[[Actinic keratosis]]
*[[Actinomycosis]]
*[[Actinomycosis]]
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*[[Arterial thrombosis]]
*[[Arterial thrombosis]]
*[[Arterio-venous malformation]]
*[[Arterio-venous malformation]]
*[[Arteriovenous fistulas]]
*Arteriovenous [[fistulas]]
*[[Arteriovenous malformation]]
*[[Arteriovenous malformation]]
*[[Atheroma]]
*[[Atheroma]]
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*[[Bacterial infection]]
*[[Bacterial infection]]
*[[Bacteroides]]
*[[Bacteroides]]
*[[Badly united fracture]]
*Badly united [[fracture]]
*[[Basal cell carcinoma]]
*[[Basal cell carcinoma]]
*[[Behcet disease ]]
*[[Behcet disease ]]
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*[[Cellulitis]]
*[[Cellulitis]]
*[[Cholesterol embolism]]
*[[Cholesterol embolism]]
*[[Chronic venous insufficiency]]
*Chronic [[venous insufficiency]]
*[[Chronically injured or diseased skin]]
*[[Chronically injured or diseased skin]]
*[[Churg-strauss syndrome]]
*[[Churg-Strauss syndrome]]
*[[Coccidiomycosis]]
*[[Coccidiomycosis]]
*[[Cold agglutinin disease]]
*[[Cold agglutinin disease]]
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*[[Crohn's disease]]
*[[Crohn's disease]]
*[[Cryoglobulinemia]]
*[[Cryoglobulinemia]]
*[[Cutaneous lymphoma]]
*Cutaneous [[lymphoma]]
*[[Decubitus ulcer]]
*[[Decubitus ulcer]]
*[[Deep vein thrombosis ]]
*[[Deep vein thrombosis ]]
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*[[Diabetic neuropathy]]
*[[Diabetic neuropathy]]
*[[Diphtheria]]
*[[Diphtheria]]
*[[dysproteinaemia]]
*[[dysproteinemia]]
*[[Ecthyma gangrenosum]]
*[[Ecthyma gangrenosum]]
*[[Ecthyma]]
*[[Impetigo | Ecthyma]]
*[[Embolism]]
*[[Embolism]]
*[[Ergotamine]]
*[[Ergotamine]]
*[[Erysipelas]]
*[[Erysipelas]]
*[[Erythema induratum of bazin]]
*[[Bazin disease | Erythema induratum of bazin]]
{{col-break|width=33%}}
*[[Essential thrombocythemia]]
*[[Essential thrombocythemia]]
{{col-break|width=33%}}
*Extravasated [[Chemotherapy | cytostatic agents]]
*[[Extravasated cytostatic agents]]
 
*[[Factitious ulceration]]
*[[Factitious ulceration]]
*[[Factor V Leiden mutation]]
*[[Factor V Leiden mutation]]
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*[[Fasciitis necroticans ]]
*[[Fasciitis necroticans ]]
*[[Felty's syndrome]]
*[[Felty's syndrome]]
*[[Fibrinolysis factors (t-PA, PAI, Plasmin)]]
*[[Filariasis]]
*[[Filariasis]]
*[[Folliculitis]]
*[[Folliculitis]]
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*[[Heat]]
*[[Heat]]
*[[Hemiplegia]]
*[[Hemiplegia]]
*[[hemophilus ducreyi]]
*[[Haemophilus ducreyi]]
*[[Hereditary spherocytosis]]
*[[Hereditary spherocytosis]]
*[[Herpes simplex]]
*[[Herpes simplex]]
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*[[Hypothermia]]
*[[Hypothermia]]
*[[Incontinence]]
*[[Incontinence]]
*[[Infantile palsy]]
*Infantile [[cerebral palsy]]
*[[Ionizing radiation]]
*[[Ionizing radiation]]
*[[Kala-azar]]
*[[Kala-azar]]
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*[[Livedoid vasculopathy]]
*[[Livedoid vasculopathy]]
*[[Low weight]]
*[[Low weight]]
*[[Lower limb fractures]]
*Lower limb [[fractures]]
*[[Lower limb nerve injury]]
*[[Lower limb nerve injury]]
*[[Lues maligna]]
*[[Lues maligna]]
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*[[Lymphangitis]]
*[[Lymphangitis]]
*[[Lymphatic obstruction]]
*[[Lymphatic obstruction]]
*[[Lymphatic vessel dysplasia]]
*Lymphatic vessel [[dysplasia]]
*[[Lymphedema]]
*[[Lymphedema]]
*[[Lymphoma ulcers]]
*[[Lymphoma]] ulcers
*[[Macroglobulinemia]]
*[[Macroglobulinemia]]
*[[Madura foot]]
*[[Eumycetoma | Madura foot]]
*[[Malnutrition]]
*[[Malnutrition]]
*[[Marjolin's ulcer]]
*[[Marjolin's ulcer]]
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*[[Mycobacterium ulcerans]]
*[[Mycobacterium ulcerans]]
*[[Mycosis fungoides]]
*[[Mycosis fungoides]]
 
*[[Myelodysplasia]]
{{col-break|width=33%}}
{{col-break|width=33%}}
*[[Myelodysplasia]]
*[[Necrobiosis lipoidica]]
*[[Necrobiosis lipoidica]]
*[[Neuropathy]]
*[[Neuropathy]]
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*[[Pemphigus vulgaris]]
*[[Pemphigus vulgaris]]
*[[Penicillin]]
*[[Penicillin]]
*[[Perforating dermatosis ]]
*[[Peripheral artery disease]]
*[[Peripheral artery disease]]
*[[Phlebitis]]
*[[Phlebitis]]
*[[Plasmin]]
*[[Plasminogen activator inhibitor-1]]
*[[Poliomyelitis]]
*[[Poliomyelitis]]
*[[Polyarteritis nodosa]]
*[[Polyarteritis nodosa]]
*[[Polyarteritis]]
*[[Polyarteritis]]
*[[polyclonal dysproteinaemia]]
*Polyclonal [[dysproteinemia]]
*[[Polycythemia vera]]
*[[Polycythemia vera]]
*[[Porphyria cutanea tarda]]
*[[Porphyria cutanea tarda]]
*[[Postthrombotic syndrome]]
*[[Post thrombotic syndrome]]
*[[Primary polycythemia]]
*[[Polycythemia vera | Primary polycythemia]]
*[[primary thrombocythemia]]
*[[Primary thrombocythemia]]
*[[Prolidase deficiency]]
*[[Prolidase deficiency]]
*[[Prolonged Immobilization]]
*[[Prolonged Immobilization]]
*[[Protein c deficiency]]
*[[Protein C deficiency]]
*[[Protein s deficiency]]
*[[Protein S deficiency]]
*[[purpura]]
*[[Purpura]]
*[[Pyoderma gangrenosum]]
*[[Pyoderma gangrenosum]]
*[[Radiation dermatitis]]
*Radiation [[dermatitis]]
*[[Raynaud's syndrome]]
*[[Raynaud's syndrome]]
*[[Rheumatoid ulcers]]
*[[Rheumatoid arthritis]]
*[[Rodent ulcer]]
*[[Rodent ulcer]]
*[[Sarcoidosis]]
*[[Sarcoidosis]]
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*[[Thrombotic thrombocytopenic purpura]]
*[[Thrombotic thrombocytopenic purpura]]
*[[Tinea pedis]]
*[[Tinea pedis]]
*[[Tissue plasminogen activator]]
*[[Tropical ulcer]]
*[[Tropical ulcer]]
*[[Tuberculosis]]
*[[Tuberculosis]]
*[[Tularemia]]
*[[Tularemia]]
*[[Ulceration pyoderma ]]
*[[Ulcerative pyoderma]]
*[[Ulcerative colitis]]
*[[Ulcerative colitis]]
*[[Vaccinations]]
*[[Vaccinations]]
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*[[Variola virus]]
*[[Variola virus]]
*[[Vasculitis]]
*[[Vasculitis]]
*[[Venous dysplasia]]
*Venous [[dysplasia]]
*[[Venous valvular incompetence]]
*[[Venous valvular incompetence]]
*[[Wegener's granulomatosis]]
*[[Wegener's granulomatosis]]
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* [[Basal cell carcinoma]]
* [[Basal cell carcinoma]]
* [[Blastomycosis]]
* [[Blastomycosis]]
* Bullous Disease
* [[Blister | Bullous Disease]]
* [[Buerger's disease]]
* [[Buerger's disease]]
* [[Burn]]s
* [[Burn]]s
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* [[Coccidiomycosis]]
* [[Coccidiomycosis]]
* [[Cold agglutinin disease]]
* [[Cold agglutinin disease]]
* Cold injury
* [[Cold injury]]
* [[Congestive Heart Failure]]
* [[Congestive Heart Failure]]
* [[Contact dermatitis]]
* [[Contact dermatitis]]
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* [[Diabetic neuropathy]]
* [[Diabetic neuropathy]]
* [[Drugs]]
* [[Drugs]]
* Ecthyma
* [[Ecthyma]]
* [[Embolism]]
* [[Embolism]]
* [[Furuncle]]
* [[Furuncle]]
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* [[Mycosis fungoides]]
* [[Mycosis fungoides]]
* [[Osteomyelitis]]
* [[Osteomyelitis]]
* Other allergic conditions
* [[Other allergic conditions]]
* [[Peripheral vascular disease]]
* [[Peripheral vascular disease]]
* [[Polyarteritis]]
* [[Polyarteritis]]
* [[Polycythemia Vera]]
* [[Polycythemia Vera]]
* Protozoal infection
* [[Protozoan infection]]
* [[Protein C deficiency]]
* [[Protein C deficiency]]
* [[Protein S deficiency]]
* [[Protein S deficiency]]

Revision as of 20:02, 18 July 2013

Leg ulcer
Disseminated Intravascular Coagulation: Gross view of thighs and legs at autopsy ecchymoses with central necrosis and ulceration looks like pyoderma gangrenosum.
Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Vendhan Ramanujam M.B.B.S [2]

Overview

Leg ulcers usually refer to ulcers of the lower leg. The most common cause of leg ulcers is venous insufficiency.

Causes[1][2]

Common Causes

Causes by Organ System

Cardiovascular Allergic vasculitis, anemia, aneurysm, angiosarcoma, arterial dysplasia, arterial insufficiency, arterial thrombosis, arterio-venous malformation, arteriovenous fistulas, arteriovenous malformation, atheroma, atherosclerosis, cholesterol embolism, chronic venous insufficiency, Churg-Strauss syndrome, congestive heart failure, deep vein thrombosis, dehydration, diabetes mellitus, embolism, heart failure, hypertension, hypotension, hypothermia, kaposi's sarcoma, leukocytoclastic vasculitis, livedoid vasculopathy, lymphangitis, lymphatic obstruction, lymphatic vessel dysplasia, lymphedema, peripheral artery disease, polyarteritis nodosa, polyarteritis, post thrombotic syndrome, raynaud's syndrome, sepsis , septic emboli, thromboangiitis obliterans, thrombotic thrombocytopenic purpura, varicose veins, vasculitis, venous dysplasia, venous valvular incompetence, Wegener's granulomatosis
Chemical/Poisoning Arsenic, noxious chemicals
Dental No underlying causes
Dermatologic Actinic keratosis, advanced age, allergic vasculitis, amoebiasis cutis, contact dermatitis, continuous trauma, Crohn's disease, decubitus ulcer, ecthyma, erysipelas, erythema induratum of bazin, filariasis, furuncle, glanders, herpes simplex, incontinence, keratoacanthoma, lymphoma ulcers, madura foot, melanoma, acquired perforating dermatosis, porphyria cutanea tarda, prolonged immobilization, radiation dermatitis, sporotrichosis, squamous cell carcinoma, ulcerative colitis, xeroderma pigmentosum
Drug Side Effect Coumarin, ergotamine, extravasated cytostatic agents, halogens, hydroxyurea, leflunomide, methotrexate, penicillin, plasmin, plasminogen activator inhibitor-1, tissue plasminogen activator
Ear Nose Throat No underlying causes
Endocrine Diabetes mellitus, necrobiosis lipoidica
Environmental Burns, cold injury, contact dermatitis, heat, ionizing radiation, noxious chemicals, radiation dermatitis
Gastroenterologic Crohn's disease, incontinence, ulcerative colitis
Genetic Arterial dysplasia, factor V Leiden mutation, gaucher's disease, hereditary spherocytosis, klinefelter syndrome, leukocyte adhesion deficiency, lymphatic vessel dysplasia, prolidase deficiency, tap1 mutation, thalassaemia, venous dysplasia, xeroderma pigmentosum
Hematologic Activated protein C resistance, anemia, antiphospholipid syndrome, antithrombin III deficiency, blood clot, cryoglobulinemia, deep vein thrombosis , dysproteinemia, essential thrombocythemia, factor V Leiden mutation, factor XIII deficiency, felty's syndrome, granulocytopenia, hereditary spherocytosis, langerhans cell histiocytosis, leukemia, leukocyte adhesion deficiency, lupus anticoagulant, macroglobulinemia, myelodysplasia, plasmin, plasminogen activator inhibitor-1, polyclonal dysproteinemia, polycythemia, polycythemia vera, primary polycythemia, primary thrombocythemia, protein C deficiency, protein S deficiency, purpura, sickle cell anemia, thalassemia, thrombotic thrombocytopenic purpura, tissue plasminogen activator
Iatrogenic Calcinosis cutis, extravasated cytostatic agents, radiation dermatitis, vaccinations
Infectious Disease Actinomycosis, amoebiasis cutis, amoebiasis, anthrax, bacillary angiomatosis, bacterial infection, bacteroides, blastomycosis, borrelia vincenti, cellulitis, coccidiomycosis, cold agglutinin disease, diphtheria, ecthyma gangrenosum , ecthyma, erysipelas, fasciitis necroticans , filariasis, folliculitis, francisella tularensis, furuncle, gas gangrene , glanders, granuloma inguinale, haemophilus ducreyi, herpes simplex, histoplasmosis, kala-azar, leishmaniasis, leprosy, lues maligna, lymphangitis, madura foot, mycobacterium ulcerans, mycosis fungoides, osteomyelitis, papillomatosis cutis carcinoides, poliomyelitis, rodent ulcer, sepsis , septic emboli, sporotrichosis, syphilis, tinea pedis, tropical ulcer, tuberculosis, tularemia, ulcerative pyoderma, variola virus, vasculitis, yaws
Musculoskeletal/Orthopedic Badly united fractures, lower limb fractures
Neurologic Alcoholic neuropathy, autonomic dysfunction, dementia, diabetic neuropathy, hemiplegia, infantile cerebral palsy, multiple sclerosis, neuropathy, spina bifida, spinal cord injury, spinal cord lesions, syringomyelia
Nutritional/Metabolic Calcinosis cutis, calciphylaxis, gout, hyperhomocysteinemia, malnutrition, necrobiosis lipoidica, porphyria cutanea tarda, starvation
Obstetric/Gynecologic No underlying causes
Oncologic Angiosarcoma, basal cell carcinoma, cold agglutinin disease, cutaneous lymphoma, leukemia, lymphoma ulcers, macroglobulinemia, marjolin's ulcer, melanoma, metastatic tumours, sarcoma, squamous cell carcinoma
Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric Delirium
Pulmonary No underlying causes
Renal/Electrolyte Calciphylaxis, incontinence
Rheumatology/Immunology/Allergy Rheumatoid arthritis
Sexual No underlying causes
Trauma Continuous trauma, lower limb fractures, lower limb nerve injury, marjolin's ulcer, shearing forces, spinal cord injury
Urologic No underlying causes
Miscellaneous Amyloidosis, artefacts, decubitus ulcer, factitious ulceration, friction, low weight, marjolin's ulcer, moisture in the form of perspiration, feces, or urine, papulosis maligna atrophicans, prolonged immobilization, sarcoidosis, spider bites

Causes in Alphabetical Order

Differential diagnosis of leg ulcer[3][4]

References

  1. ↑ "Differential diagnosis of leg ulcers - Dissemond - 2006 - JDDG: Journal der Deutschen Dermatologischen Gesellschaft - Wiley Online Library". Retrieved 12 July 2013.
  2. ↑ "http://www.health.wa.gov.au/woundswest/docs/WPR_Nov09_Atypical_Leg_Ulcers.pdf" (PDF). Retrieved 12 July 2013. External link in |title= (help)
  3. ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
  4. ↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X


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