Leg ulcer: Difference between revisions
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|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular''' | |style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular''' | ||
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Allergic vasculitis]], | |style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Allergic vasculitis]], [[anemia]], [[aneurysm]], [[angiosarcoma]], [[fibromuscular dysplasia]], [[arterial insufficiency]], [[arterial thrombosis]], [[arterio-venous malformation]], [[arteriovenous fistula]], [[arteriovenous malformation]], [[atheroma]], [[atherosclerosis]], [[cholesterol embolism]], [[venous insufficiency]], [[Churg-Strauss syndrome]], [[congestive heart failure]], [[deep vein thrombosis]], [[dehydration]], [[diabetes mellitus]], [[embolism]], [[heart failure]], [[hypertension]], [[hypotension]], [[hypothermia]], [[kaposi's sarcoma]], [[leukocytoclastic vasculitis]], [[livedoid vasculopathy]], [[lymphangitis]], [[lymphatic obstruction]], lymphatic vessel [[dysplasia]], [[lymphedema]], [[peripheral artery disease]], [[polyarteritis nodosa]], [[polyarteritis]], [[post thrombotic syndrome]], [[raynaud's syndrome]], [[sepsis ]], [[septic emboli]], [[thromboangiitis obliterans]], [[thrombotic thrombocytopenic purpura]], [[varicose veins]], [[vasculitis]], venous [[dysplasia]], [[venous valvular incompetence]], [[Wegener's granulomatosis]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Dermatologic''' | | '''Dermatologic''' | ||
|bgcolor="Beige"| [[Actinic keratosis]], | |bgcolor="Beige"| [[Actinic keratosis]], [[advanced age]], [[allergic vasculitis]], [[amebiasis cutis]], [[contact dermatitis]], [[continuous trauma]], [[Crohn's disease]], [[decubitus ulcer]], [[Impetigo | ecthyma]], [[erysipelas]], [[Bazin disease | erythema induratum of bazin]], [[filariasis]], [[furuncle]], [[glanders]], [[herpes simplex]], [[incontinence]], [[keratoacanthoma]], [[lymphoma]] ulcers, [[Eumycetoma | madura foot]], [[melanoma]], [[acquired perforating dermatosis]], [[porphyria cutanea tarda]], [[prolonged immobilization]], radiation [[dermatitis]], [[sporotrichosis]], [[squamous cell carcinoma]], [[ulcerative colitis]], [[xeroderma pigmentosum]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Drug Side Effect''' | | '''Drug Side Effect''' | ||
|bgcolor="Beige"| [[Coumarin]], | |bgcolor="Beige"| [[Coumarin]], [[ergotamine]], extravasated [[Chemotherapy | cytostatic agents]], [[halogens]], [[hydroxyurea]], [[leflunomide]], [[methotrexate]], [[penicillin]], [[plasmin]], [[plasminogen activator inhibitor-1]], [[tissue plasminogen activator]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Endocrine''' | | '''Endocrine''' | ||
|bgcolor="Beige"| [[Diabetes mellitus]], | |bgcolor="Beige"| [[Diabetes mellitus]], [[necrobiosis lipoidica]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Environmental''' | | '''Environmental''' | ||
|bgcolor="Beige"| [[Burns]], | |bgcolor="Beige"| [[Burns]], [[cold injury]], [[contact dermatitis]], [[heat]], [[ionizing radiation]], radiation [[dermatitis]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Gastroenterologic''' | | '''Gastroenterologic''' | ||
|bgcolor="Beige"| [[Crohn's disease]], | |bgcolor="Beige"| [[Crohn's disease]], [[incontinence]], [[ulcerative colitis]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Genetic''' | | '''Genetic''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Fibromuscular dysplasia]], [[factor V Leiden mutation]], [[gaucher's disease]], [[hereditary spherocytosis]], [[klinefelter syndrome]], [[leukocyte adhesion deficiency]], lymphatic vessel [[dysplasia]], [[prolidase deficiency]], [[tap1 mutation]], [[thalassaemia]], venous [[dysplasia]], [[xeroderma pigmentosum]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Hematologic''' | | '''Hematologic''' | ||
|bgcolor="Beige"| [[Activated protein C resistance]], | |bgcolor="Beige"| [[Activated protein C resistance]], [[anemia]], [[antiphospholipid syndrome]], [[antithrombin III deficiency]], [[blood clot]], [[cryoglobulinemia]], [[deep vein thrombosis ]], [[dysproteinemia]], [[essential thrombocythemia]], [[factor V Leiden mutation]], [[factor XIII deficiency]], [[felty's syndrome]], [[granulocytopenia]], [[hereditary spherocytosis]], [[langerhans cell histiocytosis]], [[leukemia]], [[leukocyte adhesion deficiency]], [[lupus anticoagulant]], [[macroglobulinemia]], [[myelodysplasia]], [[plasmin]], [[plasminogen activator inhibitor-1]], polyclonal [[dysproteinemia]], [[polycythemia]], [[polycythemia vera]], [[Polycythemia vera | primary polycythemia]], [[primary thrombocythemia]], [[protein C deficiency]], [[protein S deficiency]], [[purpura]], [[sickle cell anemia]], [[thalassemia]], [[thrombotic thrombocytopenic purpura]],[[tissue plasminogen activator]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Iatrogenic''' | | '''Iatrogenic''' | ||
|bgcolor="Beige"| [[Calcinosis cutis]], | |bgcolor="Beige"| [[Calcinosis cutis]], extravasated [[Chemotherapy | cytostatic agents]], radiation [[dermatitis]], [[vaccinations]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Infectious Disease''' | | '''Infectious Disease''' | ||
|bgcolor="Beige"| [[Actinomycosis]], | |bgcolor="Beige"| [[Actinomycosis]], [[amoebiasis]] cutis, [[amoebiasis]], [[anthrax]], [[bacillary angiomatosis]], [[bacterial infection]], [[bacteroides]], [[blastomycosis]], [[borrelia vincenti]], [[cellulitis]], [[coccidiomycosis]], [[cold agglutinin disease]], [[diphtheria]], [[ecthyma gangrenosum ]], [[Impetigo | ecthyma]], [[erysipelas]], [[fasciitis necroticans ]], [[filariasis]], [[folliculitis]], [[francisella tularensis]], [[furuncle]], [[gas gangrene ]], [[glanders]], [[granuloma inguinale]], [[haemophilus ducreyi]], [[herpes simplex]], [[histoplasmosis]], [[kala-azar]], [[leishmaniasis]], [[leprosy]], [[Syphilis | lues maligna]], [[lymphangitis]], [[Eumycetoma | madura foot]], [[mycobacterium ulcerans]], [[mycosis fungoides]], [[osteomyelitis]], [[papillomatosis cutis carcinoides]], [[poliomyelitis]], [[rodent ulcer]], [[sepsis ]], [[septic emboli]], [[sporotrichosis]], [[syphilis]], [[tinea pedis]], [[tropical ulcer]], [[tuberculosis]], [[tularemia]], [[ulcerative pyoderma]], [[variola virus]], [[vasculitis]], [[yaws]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Musculoskeletal/Orthopedic''' | | '''Musculoskeletal/Orthopedic''' | ||
|bgcolor="Beige"| Badly united [[fractures]], | |bgcolor="Beige"| Badly united [[fractures]], lower limb [[fractures]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Neurologic''' | | '''Neurologic''' | ||
|bgcolor="Beige"| [[Alcoholic neuropathy]], | |bgcolor="Beige"| [[Alcoholic neuropathy]], [[autonomic dysfunction]], [[dementia]], [[diabetic neuropathy]], [[hemiplegia]], infantile [[cerebral palsy]], [[multiple sclerosis]], [[neuropathy]], [[spina bifida]], [[spinal cord injury]], [[spinal cord lesions]], [[syringomyelia]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Nutritional/Metabolic''' | | '''Nutritional/Metabolic''' | ||
|bgcolor="Beige"| [[Calcinosis cutis]], | |bgcolor="Beige"| [[Calcinosis cutis]], [[calciphylaxis]], [[gout]], [[hyperhomocysteinemia]], [[malnutrition]], [[necrobiosis lipoidica]], [[porphyria cutanea tarda]],[[starvation]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Oncologic''' | | '''Oncologic''' | ||
|bgcolor="Beige"| [[Angiosarcoma]], | |bgcolor="Beige"| [[Angiosarcoma]], [[basal cell carcinoma]], [[cold agglutinin disease]], cutaneous [[lymphoma]], [[leukemia]], [[lymphoma]] ulcers, [[macroglobulinemia]], [[marjolin's ulcer]], [[melanoma]], [[metastatic tumours]], [[sarcoma]], [[squamous cell carcinoma]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Renal/Electrolyte''' | | '''Renal/Electrolyte''' | ||
|bgcolor="Beige"| [[Calciphylaxis]], | |bgcolor="Beige"| [[Calciphylaxis]], [[incontinence]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Trauma''' | | '''Trauma''' | ||
|bgcolor="Beige"| Continuous [[trauma]], | |bgcolor="Beige"| Continuous [[trauma]], lower limb [[fractures]], [[lower limb nerve injury]], [[marjolin's ulcer]], [[shearing forces]], [[spinal cord injury]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Miscellaneous''' | | '''Miscellaneous''' | ||
|bgcolor="Beige"| [[Amyloidosis]], | |bgcolor="Beige"| [[Amyloidosis]], [[artefacts]], [[decubitus ulcer]], [[factitious ulceration]], [[friction]], [[low weight]], [[marjolin's ulcer]], [[moisture in the form of perspiration, feces, or urine]], [[papulosis maligna atrophicans]], [[prolonged immobilization]], [[sarcoidosis]], [[spider bites]] | ||
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Revision as of 14:27, 19 July 2013
Leg ulcer | |
Disseminated Intravascular Coagulation: Gross view of thighs and legs at autopsy ecchymoses with central necrosis and ulceration looks like pyoderma gangrenosum. Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Vendhan Ramanujam M.B.B.S [2]
Overview
Leg ulcers usually refer to ulcers of the lower leg. The most common cause of leg ulcers is venous insufficiency.
Causes
Life Threatening Causes
Common Causes
- Basal Cell Carcinoma
- Decubitus ulcer
- Deep vein thrombosis
- Diabetes mellitus
- Hypertension
- Peripheral artery disease
- Rheumatoid ulcers
- Squamous cell carcinoma
- Thromboangiitis obliterans
- Venous insufficiency
- Vasculitis[1][2]
Causes by Organ System
Causes in Alphabetical Order
Differential diagnosis of leg ulcer
- Anemia
- Arteriosclerosis
- Arteriovenous malformation
- Basal cell carcinoma
- Blastomycosis
- Bullous Disease
- Buerger's disease
- Burns
- Cellulitis
- Coccidiomycosis
- Cold agglutinin disease
- Cold injury
- Congestive heart failure
- Contact dermatitis
- Decubitus ulcer
- Deep vein thrombosis
- Diabetes mellitus
- Diabetic neuropathy
- Drugs
- Ecthyma
- Embolism
- Furuncle
- Gaucher's disease
- Gout
- Histoplasmosis
- Insect bites
- Kaposi's sarcoma
- Leprosy
- Leukemia
- Lymphangitis
- Lymphedema
- Macroglobulinemia
- Malnutrition
- Melanoma
- Metastasis
- Mycosis fungoides
- Osteomyelitis
- Other allergic conditions
- Peripheral vascular disease
- Polyarteritis
- Polycythemia vera
- Protozoan infection
- Protein C deficiency
- Protein S deficiency
- Radiation dermatitis
- Raynaud's syndrome
- Rheumatoid arthritis
- Scleroderma
- Septic emboli
- Sickle cell anemia
- Sporotrichosis
- Squamous cell carcinoma
- Syringomyelia
- Systemic Lupus Erythematosus
- Tabes dorsalis
- Thalassemia
- Trauma
- Tuberculosis
- Venous insufficiency[3][4]
References
- ↑ "Differential diagnosis of leg ulcers - Dissemond - 2006 - JDDG: Journal der Deutschen Dermatologischen Gesellschaft - Wiley Online Library". Retrieved 12 July 2013.
- ↑ "http://www.health.wa.gov.au/woundswest/docs/WPR_Nov09_Atypical_Leg_Ulcers.pdf" (PDF). Retrieved 12 July 2013. External link in
|title=
(help) - ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
- ↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X