Focal segmental glomerulosclerosis historical perspective: Difference between revisions
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It is believed that Theodor Fahr, a German pathologist, first was first to describe "progressive lipoid nephrosis" in 1925 and to draw an illustration of focal segmental glomerulosclerosis (FSGS). At the time, he referred to it as "lipoid nephrosis with degeneration", showing a clear association to minimal change disease. FSGS was then described in 1957 by Dr. Arnold Rich, a pathologist at Johns Hopkins University.<ref name="pmid13426687">{{cite journal| author=RICH AR| title=A hitherto undescribed vulnerability of the juxtamedullary glomeruli in lipoid nephrosis. | journal=Bull Johns Hopkins Hosp | year= 1957 | volume= 100 | issue= 4 | pages= 173-86 | pmid=13426687 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13426687 }} </ref> His original article "A hitherto undescribed vulnerability of the juxtamedullary glomeruli in lipoid nephrosis" was originally published in "Bulletin of the Johns Hopkins Hospital".<ref name="pmid13426687">{{cite journal| author=RICH AR| title=A hitherto undescribed vulnerability of the juxtamedullary glomeruli in lipoid nephrosis. | journal=Bull Johns Hopkins Hosp | year= 1957 | volume= 100 | issue= 4 | pages= 173-86 | pmid=13426687 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13426687 }} </ref> In his original description, he noted the presence of segmental sclerosis in juxtamedullary glomeruli of autopsies of uremic children with nephrosis.<ref name="pmid13426687">{{cite journal| author=RICH AR| title=A hitherto undescribed vulnerability of the juxtamedullary glomeruli in lipoid nephrosis. | journal=Bull Johns Hopkins Hosp | year= 1957 | volume= 100 | issue= 4 | pages= 173-86 | pmid=13426687 | doi= | pmc= |url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13426687 }} </ref> | It is believed that Theodor Fahr, a German pathologist, first was first to describe "progressive lipoid nephrosis" in 1925 and to draw an illustration of focal segmental glomerulosclerosis (FSGS).<ref>{{cite book | last = Fahr |first = T | authorlink = |coauthors = | title = Pathologische anatomie des morbus brightii. In: Fahr T, Gruber GB, Koch M, et al. eds. Harnorgane Männliche Geschlechtsorgane.| publisher = Springer |date = 1925 | location = Vienna| pages = 156-472 | url = | doi = | id = | isbn = }}</ref> At the time, he referred to it as "lipoid nephrosis with degeneration", showing a clear association to minimal change disease. FSGS was then described in 1957 by Dr. Arnold Rich, a pathologist at Johns Hopkins University.<ref name="pmid13426687">{{cite journal| author=RICH AR| title=A hitherto undescribed vulnerability of the juxtamedullary glomeruli in lipoid nephrosis. | journal=Bull Johns Hopkins Hosp | year= 1957 | volume= 100 | issue= 4 | pages= 173-86 | pmid=13426687 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13426687 }} </ref> His original article "A hitherto undescribed vulnerability of the juxtamedullary glomeruli in lipoid nephrosis" was originally published in "Bulletin of the Johns Hopkins Hospital".<ref name="pmid13426687">{{cite journal| author=RICH AR| title=A hitherto undescribed vulnerability of the juxtamedullary glomeruli in lipoid nephrosis. | journal=Bull Johns Hopkins Hosp | year= 1957 | volume= 100 | issue= 4 | pages= 173-86 | pmid=13426687 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13426687 }} </ref> In his original description, he noted the presence of segmental sclerosis in juxtamedullary glomeruli of autopsies of uremic children with nephrosis.<ref name="pmid13426687">{{cite journal| author=RICH AR| title=A hitherto undescribed vulnerability of the juxtamedullary glomeruli in lipoid nephrosis. | journal=Bull Johns Hopkins Hosp | year= 1957 | volume= 100 | issue= 4 | pages= 173-86 | pmid=13426687 | doi= | pmc= |url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13426687 }} </ref> | ||
==References== | ==References== | ||
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It is believed that Theodor Fahr, a German pathologist, first was first to describe "progressive lipoid nephrosis" in 1925 and to draw an illustration of focal segmental glomerulosclerosis (FSGS).[1] At the time, he referred to it as "lipoid nephrosis with degeneration", showing a clear association to minimal change disease. FSGS was then described in 1957 by Dr. Arnold Rich, a pathologist at Johns Hopkins University.[2] His original article "A hitherto undescribed vulnerability of the juxtamedullary glomeruli in lipoid nephrosis" was originally published in "Bulletin of the Johns Hopkins Hospital".[2] In his original description, he noted the presence of segmental sclerosis in juxtamedullary glomeruli of autopsies of uremic children with nephrosis.[2]
References
- ↑ Fahr, T (1925). Pathologische anatomie des morbus brightii. In: Fahr T, Gruber GB, Koch M, et al. eds. Harnorgane Männliche Geschlechtsorgane. Vienna: Springer. pp. 156–472.
- ↑ 2.0 2.1 2.2 RICH AR (1957). "A hitherto undescribed vulnerability of the juxtamedullary glomeruli in lipoid nephrosis". Bull Johns Hopkins Hosp. 100 (4): 173–86. PMID 13426687.