Urethritis medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Medical Therapy

Pharmacotherapy

A variety of drugs may be prescribed based on the cause of the patient's urethritis. Some examples of medications based on causes include:

• Clotrimazole (Mycelex) - Trichomonas
• Doxycycline (Vibramycin) - Chlamydia
• Fluconazole (Diflucan) - Monilial
• Metronidazole (Flagyl) - Trichomonas
• Nitrofurantoin - Bacterial Infection
• Nystatin (Mycostatin) - Monilial
• Co-trimoxazole, which is a combination of Sulfamethoxazole and Trimethoprim in a ratio of 5 to 1 (Septrin, Bactrim) - Bacterial Infection

Urethritis Treatment Preferred Regimen ▸ Doxycycline 100 mg bid po x 7 days OR ▸Azithromycin 1 gm po as single dose Pregnancy ▸ Erythromycin 500 mg po qid x 7 days OR ▸Amoxicillin 500 mg po tid x 7 days Alternative Regimen ▸ Erythromycin 500 mg qid po x 7 days OR ▸Ofloxacin 300 mg q12h po x 7 days OR ▸Levofloxacin 500 mg q24h x 7 days Pregnancy ▸ Azithromycin 1 gm po single dose

Proper perineal hygiene should be stressed. This includes avoiding use of vaginal deodarant sprays and proper wiping after urination and bowel movements. Intercourse should be avoided until symptoms subside.