Creutzfeldt-Jakob disease MRI: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
|||
| Line 2: | Line 2: | ||
{{Creutzfeldt-Jakob disease}} | {{Creutzfeldt-Jakob disease}} | ||
{{CMG}} | {{CMG}} | ||
==Overview== | |||
MRI findings in CJD include high signal abnormalities in [[caudate nucleus]] and/or [[putamen]] on diffusion-weighted imaging (DWI) or fluid attenuated inversion recovery (FLAIR). | |||
== MRI== | == MRI== | ||
* MRI often shows high signal intensity in the [[caudate nucleus]] and [[putamen]] bilaterally on T2-weighted images. | * MRI often shows high signal intensity in the [[caudate nucleus]] and [[putamen]] bilaterally on T2-weighted images. | ||
* [[Diffusion Weighted Imaging]] (DWI) images are the most sensitive. In about 24% of cases DWI | * [[Diffusion Weighted Imaging]] (DWI) images are the most sensitive. In about 24% of cases, DWI showed only cortical hyperintensity, cortical and subcortical abnormalities were shown in 68% of cases and in 5%, only subcortical anomalies were present.<ref>{{cite journal|last= Young|first= Geoffrey S.|coauthors= Michael D. Geschwind, Nancy J. Fischbein, Jennifer L. Martindale, Roland G. Henry, Songling Liu, Ying Lu, Stephen Wong, Hong Liu, Bruce L. Miller and William P. Dillon|title=Diffusion-Weighted and Fluid-Attenuated Inversion Recovery Imaging in Creutzfeldt-Jakob Disease: High Sensitivity and Specificity for Diagnosis|journal=American Journal of Neuroradiology|volume= 26|pages=1551-1562|date=June-July 2005|publisher=American Society of Neuroradiology|url=http://www.ajnr.org/cgi/content/full/26/6/1551|accessdate = 2007-10-30}}</ref> | ||
* The involvement of the [[thalamus]] can be found in sCJD | * The involvement of the [[thalamus]] can be found in sCJD and is even stronger and constant in [[vCJD]].<ref>{{cite journal | last =Tschampa | first =Henriette J. |authorlink = | coauthors =Petra Mürtz, Sebastian Flacke, Sebastian Paus, Hans H. Schild and Horst Urbach | title =Thalamic Involvement in Sporadic Creutzfeldt-Jakob Disease: A Diffusion-Weighted MR Imaging Study | journal =American Journal of Neuroradiology | volume =24 | pages =908-915 | publisher =American Society of Neuroradiology |date=May 2003 | url =http://www.ajnr.org/cgi/content/full/24/5/908 | accessdate = 2007-10-30}}</ref> | ||
*An abnormal signal in the posterior thalami on T2- and diffusion-weighted images and fluid-attenuated inversion recovery sequences on brain magnetic resonance imaging (MRI); in the appropriate clinical context, this signal is highly specific for [[vCJD]]. | * An abnormal signal in the posterior thalami on T2- and diffusion-weighted images and fluid-attenuated inversion recovery sequences on brain magnetic resonance imaging (MRI); in the appropriate clinical context, this signal is highly specific for [[vCJD]]. | ||
==References== | ==References== | ||
Revision as of 03:06, 17 February 2014
|
Creutzfeldt-Jakob disease Microchapters |
|
Differentiating Creutzfeldt-Jakob disease from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Creutzfeldt-Jakob disease MRI On the Web |
|
American Roentgen Ray Society Images of Creutzfeldt-Jakob disease MRI |
|
Risk calculators and risk factors for Creutzfeldt-Jakob disease MRI |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
MRI findings in CJD include high signal abnormalities in caudate nucleus and/or putamen on diffusion-weighted imaging (DWI) or fluid attenuated inversion recovery (FLAIR).
MRI
- MRI often shows high signal intensity in the caudate nucleus and putamen bilaterally on T2-weighted images.
- Diffusion Weighted Imaging (DWI) images are the most sensitive. In about 24% of cases, DWI showed only cortical hyperintensity, cortical and subcortical abnormalities were shown in 68% of cases and in 5%, only subcortical anomalies were present.[1]
- The involvement of the thalamus can be found in sCJD and is even stronger and constant in vCJD.[2]
- An abnormal signal in the posterior thalami on T2- and diffusion-weighted images and fluid-attenuated inversion recovery sequences on brain magnetic resonance imaging (MRI); in the appropriate clinical context, this signal is highly specific for vCJD.
References
- ↑ Young, Geoffrey S. (June–July 2005). "Diffusion-Weighted and Fluid-Attenuated Inversion Recovery Imaging in Creutzfeldt-Jakob Disease: High Sensitivity and Specificity for Diagnosis". American Journal of Neuroradiology. American Society of Neuroradiology. 26: 1551–1562. Retrieved 2007-10-30. Unknown parameter
|coauthors=ignored (help) - ↑ Tschampa, Henriette J. (May 2003). "Thalamic Involvement in Sporadic Creutzfeldt-Jakob Disease: A Diffusion-Weighted MR Imaging Study". American Journal of Neuroradiology. American Society of Neuroradiology. 24: 908–915. Retrieved 2007-10-30. Unknown parameter
|coauthors=ignored (help)